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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NBPF1
Full Name:
Neuroblastoma breakpoint family member 1
Alias:
Type:
Mass (Da):
139343
Number AA:
1214
UniProt ID:
Q3BBV0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
V
V
S
A
G
P
W
S
S
E
K
A
E
T
N
Site 2
S10
V
S
A
G
P
W
S
S
E
K
A
E
T
N
I
Site 3
Y60
N
R
Q
K
K
Y
K
Y
E
E
C
K
D
L
I
Site 4
Y95
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
S
Q
Site 5
S101
Q
Y
K
V
L
V
H
S
Q
E
R
E
L
T
Q
Site 6
T107
H
S
Q
E
R
E
L
T
Q
L
R
E
K
L
R
Site 7
S120
L
R
E
G
R
D
A
S
R
S
L
N
Q
H
L
Site 8
S122
E
G
R
D
A
S
R
S
L
N
Q
H
L
Q
A
Site 9
T132
Q
H
L
Q
A
L
L
T
P
D
E
P
D
K
S
Site 10
S139
T
P
D
E
P
D
K
S
Q
G
Q
D
L
Q
E
Site 11
S163
Q
H
L
V
Q
K
L
S
P
E
N
D
E
D
E
Site 12
S186
A
E
K
V
L
E
S
S
A
P
R
E
V
Q
K
Site 13
S203
E
S
K
V
P
E
D
S
L
E
E
C
A
I
T
Site 14
T210
S
L
E
E
C
A
I
T
C
S
N
S
H
G
P
Site 15
T230
P
H
K
N
I
N
I
T
F
E
E
D
K
V
N
Site 16
S246
T
L
V
V
D
R
E
S
S
H
D
E
C
Q
D
Site 17
S247
L
V
V
D
R
E
S
S
H
D
E
C
Q
D
A
Site 18
S280
V
V
S
A
G
P
L
S
S
E
K
A
E
M
N
Site 19
S281
V
S
A
G
P
L
S
S
E
K
A
E
M
N
I
Site 20
Y329
L
A
N
Q
Q
N
K
Y
K
Y
E
E
C
E
D
Site 21
Y331
N
Q
Q
N
K
Y
K
Y
E
E
C
E
D
L
I
Site 22
S340
E
C
E
D
L
I
K
S
M
L
R
N
E
R
Q
Site 23
S517
A
L
V
V
D
R
E
S
S
H
D
E
C
Q
D
Site 24
Y600
L
A
N
Q
Q
N
K
Y
K
Y
E
E
C
K
D
Site 25
Y602
N
Q
Q
N
K
Y
K
Y
E
E
C
K
D
L
I
Site 26
S611
E
C
K
D
L
I
K
S
V
L
R
N
E
R
Q
Site 27
S705
Q
Q
L
F
Q
K
L
S
P
E
N
D
N
D
H
Site 28
S727
V
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
Site 29
S728
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
K
Site 30
S745
E
K
E
V
P
E
D
S
L
E
E
C
A
I
T
Site 31
Y760
C
S
N
S
H
G
P
Y
D
S
N
Q
P
H
R
Site 32
S762
N
S
H
G
P
Y
D
S
N
Q
P
H
R
K
T
Site 33
T769
S
N
Q
P
H
R
K
T
K
I
T
F
E
E
D
Site 34
T772
P
H
R
K
T
K
I
T
F
E
E
D
K
V
D
Site 35
S780
F
E
E
D
K
V
D
S
T
L
I
G
S
S
S
Site 36
T781
E
E
D
K
V
D
S
T
L
I
G
S
S
S
H
Site 37
S787
S
T
L
I
G
S
S
S
H
V
E
W
E
D
A
Site 38
S815
E
E
E
K
G
P
V
S
P
R
N
L
Q
E
S
Site 39
S822
S
P
R
N
L
Q
E
S
E
E
E
E
V
P
Q
Site 40
S831
E
E
E
V
P
Q
E
S
W
D
E
G
Y
S
T
Site 41
Y836
Q
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
Site 42
S837
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
Site 43
T838
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
M
Site 44
S840
D
E
G
Y
S
T
L
S
I
P
P
E
M
L
A
Site 45
S848
I
P
P
E
M
L
A
S
Y
Q
S
Y
S
G
T
Site 46
Y849
P
P
E
M
L
A
S
Y
Q
S
Y
S
G
T
F
Site 47
S851
E
M
L
A
S
Y
Q
S
Y
S
G
T
F
H
S
Site 48
T855
S
Y
Q
S
Y
S
G
T
F
H
S
L
E
E
Q
Site 49
S858
S
Y
S
G
T
F
H
S
L
E
E
Q
Q
V
C
Site 50
S891
E
A
T
G
P
R
L
S
R
E
L
L
D
E
K
Site 51
S906
G
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 52
Y911
Q
D
S
L
D
R
C
Y
S
T
P
S
G
Y
L
Site 53
S912
D
S
L
D
R
C
Y
S
T
P
S
G
Y
L
E
Site 54
T913
S
L
D
R
C
Y
S
T
P
S
G
Y
L
E
L
Site 55
S915
D
R
C
Y
S
T
P
S
G
Y
L
E
L
T
D
Site 56
T921
P
S
G
Y
L
E
L
T
D
S
C
Q
P
Y
R
Site 57
S923
G
Y
L
E
L
T
D
S
C
Q
P
Y
R
S
A
Site 58
Y927
L
T
D
S
C
Q
P
Y
R
S
A
F
Y
I
L
Site 59
Y951
D
M
D
E
I
E
K
Y
Q
E
V
E
E
D
Q
Site 60
S961
V
E
E
D
Q
D
P
S
C
P
R
L
S
R
E
Site 61
S966
D
P
S
C
P
R
L
S
R
E
L
L
D
E
K
Site 62
S981
E
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 63
Y1002
L
P
D
L
G
Q
P
Y
R
S
A
V
Y
S
L
Site 64
S1004
D
L
G
Q
P
Y
R
S
A
V
Y
S
L
E
E
Site 65
S1008
P
Y
R
S
A
V
Y
S
L
E
E
Q
Y
L
G
Site 66
S1041
G
P
P
C
P
R
L
S
R
E
L
L
E
A
V
Site 67
Y1061
Q
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
Site 68
S1062
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Site 69
T1063
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Q
Site 70
S1066
R
C
Y
S
T
P
S
S
C
L
E
Q
P
D
S
Site 71
S1073
S
C
L
E
Q
P
D
S
C
L
P
Y
G
S
S
Site 72
Y1077
Q
P
D
S
C
L
P
Y
G
S
S
F
Y
A
L
Site 73
S1080
S
C
L
P
Y
G
S
S
F
Y
A
L
E
E
K
Site 74
S1092
E
E
K
H
V
G
F
S
L
D
V
G
E
I
E
Site 75
S1112
K
K
R
R
G
R
R
S
T
K
K
R
R
R
R
Site 76
T1113
K
R
R
G
R
R
S
T
K
K
R
R
R
R
G
Site 77
S1136
N
P
P
C
P
R
L
S
G
M
L
M
E
V
E
Site 78
Y1156
Q
D
S
L
D
R
C
Y
S
T
P
S
M
Y
F
Site 79
S1157
D
S
L
D
R
C
Y
S
T
P
S
M
Y
F
E
Site 80
T1158
S
L
D
R
C
Y
S
T
P
S
M
Y
F
E
L
Site 81
S1160
D
R
C
Y
S
T
P
S
M
Y
F
E
L
P
D
Site 82
Y1162
C
Y
S
T
P
S
M
Y
F
E
L
P
D
S
F
Site 83
Y1172
L
P
D
S
F
Q
H
Y
R
S
V
F
Y
S
F
Site 84
S1174
D
S
F
Q
H
Y
R
S
V
F
Y
S
F
E
E
Site 85
S1178
H
Y
R
S
V
F
Y
S
F
E
E
Q
H
I
S
Site 86
S1185
S
F
E
E
Q
H
I
S
F
A
L
D
V
D
N
Site 87
T1196
D
V
D
N
R
F
L
T
L
M
G
T
S
L
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation