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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DAK
Full Name:
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)
Alias:
DHA kinase; Dihydroxyacetone kinase; Dihydroxyacetone kinase 2; DKFZP586B1621; Glycerone kinase; NET45
Type:
EC 2.7.1.29; Kinase (non-protein); Lipid Metabolism - glycerolipid
Mass (Da):
58959
Number AA:
575
UniProt ID:
Q3LXA3
International Prot ID:
IPI00551024
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004371
PhosphoSite+
KinaseNET
Biological Process:
GO:0006066
GO:0006071
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
S
K
K
L
V
N
S
V
A
G
C
A
D
D
Site 2
S40
G
H
R
V
A
L
R
S
D
L
D
S
L
K
G
Site 3
S44
A
L
R
S
D
L
D
S
L
K
G
R
V
A
L
Site 4
S53
K
G
R
V
A
L
L
S
G
G
G
S
G
H
E
Site 5
S57
A
L
L
S
G
G
G
S
G
H
E
P
A
H
A
Site 6
T144
I
G
D
D
S
A
F
T
V
L
K
K
A
G
R
Site 7
S199
G
V
S
L
S
S
C
S
V
P
G
S
K
P
T
Site 8
S203
S
S
C
S
V
P
G
S
K
P
T
F
E
L
S
Site 9
T206
S
V
P
G
S
K
P
T
F
E
L
S
A
D
E
Site 10
S210
S
K
P
T
F
E
L
S
A
D
E
V
E
L
G
Site 11
T246
K
L
M
L
D
H
M
T
N
T
T
N
A
S
H
Site 12
S287
I
A
D
A
T
V
R
S
L
E
G
R
G
V
K
Site 13
T345
N
V
A
A
V
S
I
T
G
R
K
R
S
R
V
Site 14
S350
S
I
T
G
R
K
R
S
R
V
A
P
A
E
P
Site 15
S363
E
P
Q
E
A
P
D
S
T
A
A
G
G
S
A
Site 16
T364
P
Q
E
A
P
D
S
T
A
A
G
G
S
A
S
Site 17
S369
D
S
T
A
A
G
G
S
A
S
K
R
M
A
L
Site 18
T406
A
G
D
G
D
C
G
T
T
H
S
R
A
A
R
Site 19
S409
G
D
C
G
T
T
H
S
R
A
A
R
A
I
Q
Site 20
S427
K
E
G
P
P
P
A
S
P
A
Q
L
L
S
K
Site 21
S436
A
Q
L
L
S
K
L
S
V
L
L
L
E
K
M
Site 22
S467
Q
P
L
K
A
K
T
S
L
P
A
W
S
A
A
Site 23
Y485
G
L
E
A
M
Q
K
Y
G
K
A
A
P
G
D
Site 24
T494
K
A
A
P
G
D
R
T
M
L
D
S
L
W
A
Site 25
S498
G
D
R
T
M
L
D
S
L
W
A
A
G
Q
E
Site 26
S511
Q
E
L
Q
A
W
K
S
P
G
A
D
L
L
Q
Site 27
S545
E
A
G
A
G
R
A
S
Y
I
S
S
A
R
L
Site 28
Y546
A
G
A
G
R
A
S
Y
I
S
S
A
R
L
E
Site 29
S548
A
G
R
A
S
Y
I
S
S
A
R
L
E
Q
P
Site 30
S549
G
R
A
S
Y
I
S
S
A
R
L
E
Q
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation