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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGL3
Full Name:
Ral guanine nucleotide dissociation stimulator-like 3
Alias:
FLJ00153 protein; RalGDS-like 3
Type:
Unknown function
Mass (Da):
78107
Number AA:
710
UniProt ID:
Q3MIN7
International Prot ID:
IPI00643373
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0044464
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005085
GO:0030234
GO:0030695
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0007165
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
T
E
D
G
A
V
Y
S
V
S
L
R
R
Q
R
Site 2
S30
D
G
A
V
Y
S
V
S
L
R
R
Q
R
S
Q
Site 3
S36
V
S
L
R
R
Q
R
S
Q
R
R
S
P
A
E
Site 4
S40
R
Q
R
S
Q
R
R
S
P
A
E
G
P
G
G
Site 5
S48
P
A
E
G
P
G
G
S
Q
A
P
S
P
I
A
Site 6
S52
P
G
G
S
Q
A
P
S
P
I
A
N
T
F
L
Site 7
S64
T
F
L
H
Y
R
T
S
K
V
R
V
L
R
A
Site 8
S91
G
D
R
E
Q
D
P
S
F
M
P
A
F
L
A
Site 9
T130
P
G
V
E
I
K
K
T
A
V
Q
D
L
S
F
Site 10
S136
K
T
A
V
Q
D
L
S
F
N
K
N
L
R
A
Site 11
S166
F
R
D
P
P
V
H
S
D
L
G
S
V
R
T
Site 12
S170
P
V
H
S
D
L
G
S
V
R
T
F
L
G
W
Site 13
S182
L
G
W
A
A
P
G
S
A
E
A
Q
K
A
E
Site 14
T212
E
E
P
P
Q
V
W
T
G
P
P
R
V
A
Q
Site 15
T220
G
P
P
R
V
A
Q
T
S
D
P
D
S
S
E
Site 16
S221
P
P
R
V
A
Q
T
S
D
P
D
S
S
E
A
Site 17
S225
A
Q
T
S
D
P
D
S
S
E
A
C
A
E
E
Site 18
S226
Q
T
S
D
P
D
S
S
E
A
C
A
E
E
E
Site 19
S247
G
P
Q
L
L
D
F
S
V
D
E
V
A
E
Q
Site 20
S274
R
L
Y
E
C
L
G
S
V
W
S
Q
R
D
R
Site 21
S277
E
C
L
G
S
V
W
S
Q
R
D
R
P
G
A
Site 22
S288
R
P
G
A
A
G
A
S
P
T
V
R
A
T
V
Site 23
S341
C
R
E
L
R
N
F
S
S
L
R
A
I
L
S
Site 24
S342
R
E
L
R
N
F
S
S
L
R
A
I
L
S
A
Site 25
Y356
A
L
Q
S
N
P
I
Y
R
L
K
R
S
W
G
Site 26
S361
P
I
Y
R
L
K
R
S
W
G
A
V
S
R
E
Site 27
S366
K
R
S
W
G
A
V
S
R
E
P
L
S
T
F
Site 28
S371
A
V
S
R
E
P
L
S
T
F
R
K
L
S
Q
Site 29
T372
V
S
R
E
P
L
S
T
F
R
K
L
S
Q
I
Site 30
S377
L
S
T
F
R
K
L
S
Q
I
F
S
D
E
N
Site 31
S381
R
K
L
S
Q
I
F
S
D
E
N
N
H
L
S
Site 32
S388
S
D
E
N
N
H
L
S
S
R
E
I
L
F
Q
Site 33
T408
G
S
Q
E
E
D
N
T
P
G
S
L
P
S
K
Site 34
S411
E
E
D
N
T
P
G
S
L
P
S
K
P
P
P
Site 35
S414
N
T
P
G
S
L
P
S
K
P
P
P
G
P
V
Site 36
Y423
P
P
P
G
P
V
P
Y
L
G
T
F
L
T
D
Site 37
S471
Q
L
Q
R
R
C
Q
S
Y
T
L
S
P
H
P
Site 38
Y472
L
Q
R
R
C
Q
S
Y
T
L
S
P
H
P
P
Site 39
T473
Q
R
R
C
Q
S
Y
T
L
S
P
H
P
P
I
Site 40
S475
R
C
Q
S
Y
T
L
S
P
H
P
P
I
L
A
Site 41
T491
L
H
A
Q
N
Q
L
T
E
E
Q
S
Y
R
L
Site 42
S495
N
Q
L
T
E
E
Q
S
Y
R
L
S
R
V
I
Site 43
Y496
Q
L
T
E
E
Q
S
Y
R
L
S
R
V
I
E
Site 44
S499
E
E
Q
S
Y
R
L
S
R
V
I
E
P
P
A
Site 45
S508
V
I
E
P
P
A
A
S
C
P
S
S
P
R
I
Site 46
S511
P
P
A
A
S
C
P
S
S
P
R
I
R
R
R
Site 47
S512
P
A
A
S
C
P
S
S
P
R
I
R
R
R
I
Site 48
S520
P
R
I
R
R
R
I
S
L
T
K
R
L
S
A
Site 49
T522
I
R
R
R
I
S
L
T
K
R
L
S
A
K
L
Site 50
S526
I
S
L
T
K
R
L
S
A
K
L
A
R
E
K
Site 51
S534
A
K
L
A
R
E
K
S
S
S
P
S
G
S
P
Site 52
S536
L
A
R
E
K
S
S
S
P
S
G
S
P
G
D
Site 53
S538
R
E
K
S
S
S
P
S
G
S
P
G
D
P
S
Site 54
S540
K
S
S
S
P
S
G
S
P
G
D
P
S
S
P
Site 55
S545
S
G
S
P
G
D
P
S
S
P
T
S
S
V
S
Site 56
S546
G
S
P
G
D
P
S
S
P
T
S
S
V
S
P
Site 57
T548
P
G
D
P
S
S
P
T
S
S
V
S
P
G
S
Site 58
S549
G
D
P
S
S
P
T
S
S
V
S
P
G
S
P
Site 59
S550
D
P
S
S
P
T
S
S
V
S
P
G
S
P
P
Site 60
S552
S
S
P
T
S
S
V
S
P
G
S
P
P
S
S
Site 61
S555
T
S
S
V
S
P
G
S
P
P
S
S
P
R
S
Site 62
S558
V
S
P
G
S
P
P
S
S
P
R
S
R
D
A
Site 63
S559
S
P
G
S
P
P
S
S
P
R
S
R
D
A
P
Site 64
S562
S
P
P
S
S
P
R
S
R
D
A
P
A
G
S
Site 65
S569
S
R
D
A
P
A
G
S
P
P
A
S
P
G
P
Site 66
S573
P
A
G
S
P
P
A
S
P
G
P
Q
G
P
S
Site 67
S580
S
P
G
P
Q
G
P
S
T
K
L
P
L
S
L
Site 68
T581
P
G
P
Q
G
P
S
T
K
L
P
L
S
L
D
Site 69
S586
P
S
T
K
L
P
L
S
L
D
L
P
S
P
R
Site 70
S591
P
L
S
L
D
L
P
S
P
R
P
F
A
L
P
Site 71
S601
P
F
A
L
P
L
G
S
P
R
I
P
L
P
A
Site 72
S611
I
P
L
P
A
Q
Q
S
S
E
A
R
V
I
R
Site 73
S612
P
L
P
A
Q
Q
S
S
E
A
R
V
I
R
V
Site 74
S620
E
A
R
V
I
R
V
S
I
D
N
D
H
G
N
Site 75
Y629
D
N
D
H
G
N
L
Y
R
S
I
L
L
T
S
Site 76
S631
D
H
G
N
L
Y
R
S
I
L
L
T
S
Q
D
Site 77
T635
L
Y
R
S
I
L
L
T
S
Q
D
K
A
P
S
Site 78
S636
Y
R
S
I
L
L
T
S
Q
D
K
A
P
S
V
Site 79
S642
T
S
Q
D
K
A
P
S
V
V
R
R
A
L
Q
Site 80
Y661
P
Q
P
W
A
C
D
Y
Q
L
F
Q
V
L
P
Site 81
T701
M
L
R
R
K
E
G
T
R
N
T
L
S
V
S
Site 82
T704
R
K
E
G
T
R
N
T
L
S
V
S
P
S
_
Site 83
S706
E
G
T
R
N
T
L
S
V
S
P
S
_
_
_
Site 84
S708
T
R
N
T
L
S
V
S
P
S
_
_
_
_
_
Site 85
S710
N
T
L
S
V
S
P
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation