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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC144B
Full Name:
Coiled-coil domain-containing protein 144B
Alias:
Type:
Mass (Da):
82951
Number AA:
725
UniProt ID:
Q3MJ40
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
R
G
G
A
E
G
S
P
K
L
A
V
Y
A
Site 2
Y21
G
S
P
K
L
A
V
Y
A
T
R
K
T
R
S
Site 3
T26
A
V
Y
A
T
R
K
T
R
S
V
R
S
Q
E
Site 4
S28
Y
A
T
R
K
T
R
S
V
R
S
Q
E
D
Q
Site 5
S31
R
K
T
R
S
V
R
S
Q
E
D
Q
W
Y
L
Site 6
Y37
R
S
Q
E
D
Q
W
Y
L
G
Y
P
G
D
Q
Site 7
Y40
E
D
Q
W
Y
L
G
Y
P
G
D
Q
W
S
S
Site 8
S57
S
Y
S
W
W
K
N
S
V
G
S
E
S
K
H
Site 9
S60
W
W
K
N
S
V
G
S
E
S
K
H
G
E
G
Site 10
S115
D
K
R
D
R
K
K
S
I
Q
Q
L
V
P
E
Site 11
T128
P
E
Y
K
E
K
Q
T
P
E
S
L
P
Q
N
Site 12
S131
K
E
K
Q
T
P
E
S
L
P
Q
N
N
N
P
Site 13
T146
D
W
H
P
T
N
L
T
L
S
D
E
T
C
Q
Site 14
S148
H
P
T
N
L
T
L
S
D
E
T
C
Q
R
S
Site 15
T151
N
L
T
L
S
D
E
T
C
Q
R
S
K
N
L
Site 16
S164
N
L
K
V
G
D
K
S
P
S
V
S
P
S
M
Site 17
S166
K
V
G
D
K
S
P
S
V
S
P
S
M
P
E
Site 18
S168
G
D
K
S
P
S
V
S
P
S
M
P
E
N
Q
Site 19
S170
K
S
P
S
V
S
P
S
M
P
E
N
Q
S
A
Site 20
S176
P
S
M
P
E
N
Q
S
A
T
K
E
L
G
Q
Site 21
T187
E
L
G
Q
M
N
L
T
E
R
E
K
M
D
T
Site 22
T194
T
E
R
E
K
M
D
T
G
V
V
L
L
S
G
Site 23
S200
D
T
G
V
V
L
L
S
G
N
D
T
L
H
D
Site 24
T204
V
L
L
S
G
N
D
T
L
H
D
L
C
Q
S
Site 25
S211
T
L
H
D
L
C
Q
S
Q
L
P
E
N
K
E
Site 26
S219
Q
L
P
E
N
K
E
S
K
E
A
E
Q
D
L
Site 27
S249
N
K
Q
P
Q
K
T
S
Q
E
P
E
M
A
K
Site 28
Y266
D
R
E
D
I
P
I
Y
P
V
L
P
H
V
Q
Site 29
Y306
K
Q
R
F
G
E
I
Y
E
K
Y
K
I
P
A
Site 30
Y309
F
G
E
I
Y
E
K
Y
K
I
P
A
C
P
E
Site 31
S324
E
E
P
L
L
D
N
S
T
R
G
T
D
V
K
Site 32
T328
L
D
N
S
T
R
G
T
D
V
K
D
I
P
F
Site 33
T338
K
D
I
P
F
N
L
T
N
N
I
P
G
C
E
Site 34
S350
G
C
E
E
E
D
A
S
E
I
S
V
S
V
V
Site 35
S353
E
E
D
A
S
E
I
S
V
S
V
V
F
E
T
Site 36
S368
F
P
E
Q
K
E
P
S
L
K
N
I
I
H
P
Site 37
Y376
L
K
N
I
I
H
P
Y
Y
H
P
Y
S
G
S
Site 38
Y377
K
N
I
I
H
P
Y
Y
H
P
Y
S
G
S
Q
Site 39
S390
S
Q
E
H
V
C
Q
S
S
S
K
L
H
L
H
Site 40
S392
E
H
V
C
Q
S
S
S
K
L
H
L
H
E
N
Site 41
T437
A
R
N
P
E
V
V
T
V
E
M
K
E
D
Q
Site 42
S458
T
K
N
M
N
Q
N
S
D
S
G
S
T
N
N
Site 43
S460
N
M
N
Q
N
S
D
S
G
S
T
N
N
Y
K
Site 44
S462
N
Q
N
S
D
S
G
S
T
N
N
Y
K
S
L
Site 45
Y466
D
S
G
S
T
N
N
Y
K
S
L
K
P
K
L
Site 46
S468
G
S
T
N
N
Y
K
S
L
K
P
K
L
E
N
Site 47
S477
K
P
K
L
E
N
L
S
S
L
P
P
D
S
D
Site 48
S478
P
K
L
E
N
L
S
S
L
P
P
D
S
D
R
Site 49
S483
L
S
S
L
P
P
D
S
D
R
T
S
E
V
Y
Site 50
T486
L
P
P
D
S
D
R
T
S
E
V
Y
L
H
E
Site 51
S487
P
P
D
S
D
R
T
S
E
V
Y
L
H
E
E
Site 52
Y490
S
D
R
T
S
E
V
Y
L
H
E
E
L
Q
Q
Site 53
S536
E
E
M
E
K
H
R
S
N
S
T
E
L
S
G
Site 54
S538
M
E
K
H
R
S
N
S
T
E
L
S
G
T
L
Site 55
S542
R
S
N
S
T
E
L
S
G
T
L
T
D
G
T
Site 56
T544
N
S
T
E
L
S
G
T
L
T
D
G
T
T
V
Site 57
T546
T
E
L
S
G
T
L
T
D
G
T
T
V
G
N
Site 58
T549
S
G
T
L
T
D
G
T
T
V
G
N
D
D
D
Site 59
T550
G
T
L
T
D
G
T
T
V
G
N
D
D
D
G
Site 60
T577
H
D
R
P
A
D
K
T
A
N
E
K
N
K
V
Site 61
Y589
N
K
V
K
N
Q
I
Y
P
E
A
D
F
A
D
Site 62
S597
P
E
A
D
F
A
D
S
M
E
P
S
E
I
A
Site 63
S601
F
A
D
S
M
E
P
S
E
I
A
S
E
D
C
Site 64
S605
M
E
P
S
E
I
A
S
E
D
C
E
L
S
H
Site 65
S611
A
S
E
D
C
E
L
S
H
S
V
Y
E
N
F
Site 66
Y629
I
E
Q
L
R
M
E
Y
K
D
S
A
S
L
P
Site 67
S632
L
R
M
E
Y
K
D
S
A
S
L
P
R
I
Q
Site 68
S634
M
E
Y
K
D
S
A
S
L
P
R
I
Q
D
T
Site 69
T660
N
N
H
C
D
Q
L
T
V
K
L
K
Q
M
E
Site 70
S671
K
Q
M
E
N
M
V
S
V
L
Q
N
E
L
S
Site 71
S678
S
V
L
Q
N
E
L
S
E
T
K
K
T
K
L
Site 72
T680
L
Q
N
E
L
S
E
T
K
K
T
K
L
Q
L
Site 73
T683
E
L
S
E
T
K
K
T
K
L
Q
L
E
L
Q
Site 74
Y699
I
E
W
E
K
E
L
Y
D
L
R
L
A
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation