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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BBS9
Full Name:
Protein PTHB1
Alias:
Bardet-Biedl syndrome 9 protein;Parathyroid hormone-responsive B1 gene protein
Type:
Mass (Da):
99280
Number AA:
887
UniProt ID:
Q3SYG4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
L
F
K
A
R
D
W
Site 2
T12
K
A
R
D
W
W
S
T
I
L
G
D
K
E
E
Site 3
S53
M
G
Y
L
R
I
F
S
P
H
P
A
K
T
G
Site 4
Y106
H
S
R
K
L
C
V
Y
S
V
S
G
T
L
G
Site 5
S107
S
R
K
L
C
V
Y
S
V
S
G
T
L
G
N
Site 6
Y140
R
T
A
C
N
M
T
Y
G
S
F
G
G
V
K
Site 7
S142
A
C
N
M
T
Y
G
S
F
G
G
V
K
G
R
Site 8
Y169
M
V
F
E
Q
E
S
Y
A
F
G
R
F
L
P
Site 9
S187
L
P
G
P
L
A
Y
S
S
R
T
D
S
F
L
Site 10
S188
P
G
P
L
A
Y
S
S
R
T
D
S
F
L
T
Site 11
S192
A
Y
S
S
R
T
D
S
F
L
T
V
S
S
C
Site 12
T195
S
R
T
D
S
F
L
T
V
S
S
C
Q
Q
V
Site 13
S197
T
D
S
F
L
T
V
S
S
C
Q
Q
V
E
S
Site 14
Y205
S
C
Q
Q
V
E
S
Y
K
Y
Q
V
L
A
F
Site 15
Y207
Q
Q
V
E
S
Y
K
Y
Q
V
L
A
F
A
T
Site 16
T222
D
A
D
K
R
Q
E
T
E
Q
Q
K
L
G
S
Site 17
T238
K
R
L
V
V
D
W
T
L
N
I
G
E
Q
A
Site 18
S259
S
F
N
Q
S
A
S
S
V
F
V
L
G
E
R
Site 19
Y293
S
P
S
C
F
L
P
Y
C
S
V
S
E
G
T
Site 20
S357
D
D
G
H
L
Q
C
S
Y
L
G
T
D
P
S
Site 21
Y358
D
G
H
L
Q
C
S
Y
L
G
T
D
P
S
L
Site 22
S364
S
Y
L
G
T
D
P
S
L
F
Q
A
P
N
V
Site 23
T405
S
Q
G
V
W
P
M
T
E
R
E
D
D
L
N
Site 24
S414
R
E
D
D
L
N
V
S
V
V
V
S
P
N
F
Site 25
S423
V
V
S
P
N
F
D
S
V
S
Q
A
T
D
V
Site 26
S425
S
P
N
F
D
S
V
S
Q
A
T
D
V
E
V
Site 27
Y460
Q
K
A
K
L
S
V
Y
V
Q
P
P
L
E
L
Site 28
T468
V
Q
P
P
L
E
L
T
C
D
Q
F
T
F
E
Site 29
T478
Q
F
T
F
E
F
M
T
P
D
L
T
R
T
V
Site 30
S486
P
D
L
T
R
T
V
S
F
S
V
Y
L
K
R
Site 31
S488
L
T
R
T
V
S
F
S
V
Y
L
K
R
S
Y
Site 32
Y490
R
T
V
S
F
S
V
Y
L
K
R
S
Y
T
P
Site 33
S494
F
S
V
Y
L
K
R
S
Y
T
P
S
E
L
E
Site 34
Y495
S
V
Y
L
K
R
S
Y
T
P
S
E
L
E
G
Site 35
T496
V
Y
L
K
R
S
Y
T
P
S
E
L
E
G
N
Site 36
S498
L
K
R
S
Y
T
P
S
E
L
E
G
N
A
V
Site 37
S507
L
E
G
N
A
V
V
S
Y
S
R
P
T
D
R
Site 38
Y508
E
G
N
A
V
V
S
Y
S
R
P
T
D
R
N
Site 39
T512
V
V
S
Y
S
R
P
T
D
R
N
P
D
G
I
Site 40
S541
I
C
L
P
G
Q
P
S
K
T
A
S
H
K
I
Site 41
T543
L
P
G
Q
P
S
K
T
A
S
H
K
I
T
I
Site 42
S545
G
Q
P
S
K
T
A
S
H
K
I
T
I
D
T
Site 43
T549
K
T
A
S
H
K
I
T
I
D
T
N
K
S
P
Site 44
T552
S
H
K
I
T
I
D
T
N
K
S
P
V
S
L
Site 45
S558
D
T
N
K
S
P
V
S
L
L
S
L
F
P
G
Site 46
S568
S
L
F
P
G
F
A
S
Q
S
D
D
D
Q
V
Site 47
S570
F
P
G
F
A
S
Q
S
D
D
D
Q
V
N
V
Site 48
S596
T
V
L
A
S
K
T
S
Q
R
Y
R
I
Q
S
Site 49
S603
S
Q
R
Y
R
I
Q
S
E
Q
F
E
D
L
W
Site 50
Y623
L
I
L
R
L
Q
E
Y
F
E
K
Q
G
V
K
Site 51
S637
K
D
F
A
C
S
F
S
G
S
I
P
L
Q
E
Site 52
Y645
G
S
I
P
L
Q
E
Y
F
E
L
I
D
H
H
Site 53
S667
E
K
L
E
E
L
L
S
E
R
A
V
Q
F
R
Site 54
T688
L
A
R
F
K
D
K
T
P
A
P
L
Q
H
L
Site 55
T697
A
P
L
Q
H
L
D
T
L
L
D
G
T
Y
K
Site 56
S723
N
Q
G
N
L
F
Q
S
F
T
R
L
K
S
A
Site 57
T725
G
N
L
F
Q
S
F
T
R
L
K
S
A
T
H
Site 58
T771
Q
E
L
G
W
E
E
T
V
D
A
A
I
S
H
Site 59
T782
A
I
S
H
L
L
K
T
C
L
S
K
S
S
K
Site 60
S785
H
L
L
K
T
C
L
S
K
S
S
K
E
Q
A
Site 61
S787
L
K
T
C
L
S
K
S
S
K
E
Q
A
L
N
Site 62
S797
E
Q
A
L
N
L
N
S
Q
L
N
I
P
K
D
Site 63
S806
L
N
I
P
K
D
T
S
Q
L
K
K
H
I
T
Site 64
T813
S
Q
L
K
K
H
I
T
L
L
C
D
R
L
S
Site 65
S828
K
G
G
R
L
C
L
S
T
D
A
A
A
P
Q
Site 66
T829
G
G
R
L
C
L
S
T
D
A
A
A
P
Q
T
Site 67
S849
G
C
T
T
I
P
E
S
D
L
E
E
R
S
V
Site 68
S855
E
S
D
L
E
E
R
S
V
E
Q
D
S
T
E
Site 69
S860
E
R
S
V
E
Q
D
S
T
E
L
F
T
N
H
Site 70
T861
R
S
V
E
Q
D
S
T
E
L
F
T
N
H
R
Site 71
T871
F
T
N
H
R
H
L
T
A
E
T
P
R
P
E
Site 72
T874
H
R
H
L
T
A
E
T
P
R
P
E
V
S
P
Site 73
S880
E
T
P
R
P
E
V
S
P
L
Q
G
V
S
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation