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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARF
Full Name:
Putative GTP-binding protein Parf
Alias:
BA216L13.9; Chromosome 9 open reading frame 86; FLJ10101; FLJ13045; GTP-binding protein Parf; Partner of ARF; Pp8875; Rab-like protein 1; RBEL1
Type:
G protein, monomeric (non-Rab)
Mass (Da):
79549
Number AA:
729
UniProt ID:
Q3YEC7
International Prot ID:
IPI00827967
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0007165
GO:0007242
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
N
I
P
A
G
L
Q
S
M
N
Q
A
L
Q
R
Site 2
Y42
R
F
A
K
G
V
Q
Y
N
M
K
I
V
I
R
Site 3
T54
V
I
R
G
D
R
N
T
G
K
T
A
L
W
H
Site 4
T57
G
D
R
N
T
G
K
T
A
L
W
H
R
L
Q
Site 5
Y72
G
R
P
F
V
E
E
Y
I
P
T
Q
E
I
Q
Site 6
T75
F
V
E
E
Y
I
P
T
Q
E
I
Q
V
T
S
Site 7
Y137
D
A
E
F
L
D
V
Y
K
N
C
N
G
V
V
Site 8
T150
V
V
M
M
F
D
I
T
K
Q
W
T
F
N
Y
Site 9
Y157
T
K
Q
W
T
F
N
Y
I
L
R
E
L
P
K
Site 10
Y177
P
V
C
V
L
G
N
Y
R
D
M
G
E
H
R
Site 11
S204
N
L
D
R
P
P
G
S
S
Y
F
R
Y
A
E
Site 12
S205
L
D
R
P
P
G
S
S
Y
F
R
Y
A
E
S
Site 13
Y206
D
R
P
P
G
S
S
Y
F
R
Y
A
E
S
S
Site 14
Y209
P
G
S
S
Y
F
R
Y
A
E
S
S
M
K
N
Site 15
S212
S
Y
F
R
Y
A
E
S
S
M
K
N
S
F
G
Site 16
S213
Y
F
R
Y
A
E
S
S
M
K
N
S
F
G
L
Site 17
S217
A
E
S
S
M
K
N
S
F
G
L
K
Y
L
H
Site 18
Y222
K
N
S
F
G
L
K
Y
L
H
K
F
F
N
I
Site 19
T238
F
L
Q
L
Q
R
E
T
L
L
R
Q
L
E
T
Site 20
T253
N
Q
L
D
M
D
A
T
L
E
E
L
S
V
Q
Site 21
S258
D
A
T
L
E
E
L
S
V
Q
Q
E
T
E
D
Site 22
Y268
Q
E
T
E
D
Q
N
Y
G
I
F
L
E
M
M
Site 23
S284
A
R
S
R
G
H
A
S
P
L
A
A
N
G
Q
Site 24
S292
P
L
A
A
N
G
Q
S
P
S
P
G
S
Q
S
Site 25
S294
A
A
N
G
Q
S
P
S
P
G
S
Q
S
P
V
Site 26
S297
G
Q
S
P
S
P
G
S
Q
S
P
V
V
P
A
Site 27
S299
S
P
S
P
G
S
Q
S
P
V
V
P
A
G
A
Site 28
T309
V
P
A
G
A
V
S
T
G
S
S
S
P
G
T
Site 29
S311
A
G
A
V
S
T
G
S
S
S
P
G
T
P
Q
Site 30
S312
G
A
V
S
T
G
S
S
S
P
G
T
P
Q
P
Site 31
S313
A
V
S
T
G
S
S
S
P
G
T
P
Q
P
A
Site 32
T316
T
G
S
S
S
P
G
T
P
Q
P
A
P
Q
L
Site 33
S331
P
L
N
A
A
P
P
S
S
V
P
P
V
P
P
Site 34
S332
L
N
A
A
P
P
S
S
V
P
P
V
P
P
S
Site 35
S339
S
V
P
P
V
P
P
S
E
A
L
P
P
P
A
Site 36
S349
L
P
P
P
A
C
P
S
A
P
A
P
R
R
S
Site 37
S356
S
A
P
A
P
R
R
S
I
I
S
R
L
F
G
Site 38
S359
A
P
R
R
S
I
I
S
R
L
F
G
T
S
P
Site 39
S365
I
S
R
L
F
G
T
S
P
A
T
E
A
A
P
Site 40
T386
P
A
A
E
G
P
A
T
V
Q
S
V
E
D
F
Site 41
S389
E
G
P
A
T
V
Q
S
V
E
D
F
V
P
D
Site 42
S402
P
D
D
R
L
D
R
S
F
L
E
D
T
T
P
Site 43
T408
R
S
F
L
E
D
T
T
P
A
R
D
E
K
K
Site 44
S425
A
K
A
A
Q
Q
D
S
D
S
D
G
E
A
L
Site 45
S427
A
A
Q
Q
D
S
D
S
D
G
E
A
L
G
G
Site 46
S454
L
E
D
Q
P
R
G
S
P
P
L
P
A
G
P
Site 47
S464
L
P
A
G
P
V
P
S
Q
D
I
T
L
S
S
Site 48
T468
P
V
P
S
Q
D
I
T
L
S
S
E
E
E
A
Site 49
S470
P
S
Q
D
I
T
L
S
S
E
E
E
A
E
V
Site 50
S471
S
Q
D
I
T
L
S
S
E
E
E
A
E
V
A
Site 51
S492
A
P
A
P
Q
Q
C
S
E
P
E
T
K
W
S
Site 52
T496
Q
Q
C
S
E
P
E
T
K
W
S
S
I
P
A
Site 53
S499
S
E
P
E
T
K
W
S
S
I
P
A
S
K
P
Site 54
S500
E
P
E
T
K
W
S
S
I
P
A
S
K
P
R
Site 55
S504
K
W
S
S
I
P
A
S
K
P
R
R
G
T
A
Site 56
T510
A
S
K
P
R
R
G
T
A
P
T
R
T
A
A
Site 57
T513
P
R
R
G
T
A
P
T
R
T
A
A
P
P
W
Site 58
T515
R
G
T
A
P
T
R
T
A
A
P
P
W
P
G
Site 59
S525
P
P
W
P
G
G
V
S
V
R
T
G
P
E
K
Site 60
S535
T
G
P
E
K
R
S
S
T
R
P
P
A
E
M
Site 61
T536
G
P
E
K
R
S
S
T
R
P
P
A
E
M
E
Site 62
S551
P
G
K
G
E
Q
A
S
S
S
E
S
D
P
E
Site 63
S552
G
K
G
E
Q
A
S
S
S
E
S
D
P
E
G
Site 64
S553
K
G
E
Q
A
S
S
S
E
S
D
P
E
G
P
Site 65
S555
E
Q
A
S
S
S
E
S
D
P
E
G
P
I
A
Site 66
S577
M
D
D
P
D
F
E
S
E
G
S
D
T
Q
R
Site 67
S580
P
D
F
E
S
E
G
S
D
T
Q
R
R
A
D
Site 68
T582
F
E
S
E
G
S
D
T
Q
R
R
A
D
D
F
Site 69
S596
F
P
V
R
D
D
P
S
D
V
T
D
E
D
E
Site 70
T599
R
D
D
P
S
D
V
T
D
E
D
E
G
P
A
Site 71
S640
E
E
A
G
P
K
E
S
S
E
E
G
K
E
G
Site 72
S641
E
A
G
P
K
E
S
S
E
E
G
K
E
G
K
Site 73
T649
E
E
G
K
E
G
K
T
P
S
K
E
K
K
K
Site 74
S651
G
K
E
G
K
T
P
S
K
E
K
K
K
K
K
Site 75
S673
E
K
A
A
K
K
K
S
K
H
K
K
S
K
D
Site 76
S678
K
K
S
K
H
K
K
S
K
D
K
E
E
G
K
Site 77
S698
R
Q
Q
R
P
P
R
S
R
E
R
T
A
A
D
Site 78
T702
P
P
R
S
R
E
R
T
A
A
D
E
L
E
A
Site 79
Y726
R
H
P
G
G
G
D
Y
E
E
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation