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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RP11-631M21.2
Full Name:
Tubulin beta-8 chain
Alias:
FLJ40100; Rp11-631m21.2; Tbb8; Tubb8; Tubulin, beta 8
Type:
Mass (Da):
49776
Number AA:
444
UniProt ID:
Q3ZCM7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
GO:0043234
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0003924
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0051258
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
A
K
F
W
E
V
I
S
D
E
H
A
I
D
S
Site 2
Y36
A
I
D
S
A
G
T
Y
H
G
D
S
H
L
Q
Site 3
S40
A
G
T
Y
H
G
D
S
H
L
Q
L
E
R
I
Site 4
Y50
Q
L
E
R
I
N
V
Y
Y
N
E
A
S
G
G
Site 5
Y51
L
E
R
I
N
V
Y
Y
N
E
A
S
G
G
R
Site 6
Y59
N
E
A
S
G
G
R
Y
V
P
R
A
V
L
V
Site 7
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Site 8
S75
L
E
P
G
T
M
D
S
V
R
S
G
P
F
G
Site 9
S78
G
T
M
D
S
V
R
S
G
P
F
G
Q
V
F
Site 10
S115
E
G
A
E
L
M
E
S
V
M
D
V
V
R
K
Site 11
S126
V
V
R
K
E
A
E
S
C
D
C
L
Q
G
F
Site 12
S138
Q
G
F
Q
L
T
H
S
L
G
G
G
T
G
S
Site 13
S153
G
M
G
T
L
L
L
S
K
I
R
E
E
Y
P
Site 14
Y159
L
S
K
I
R
E
E
Y
P
D
R
I
I
N
T
Site 15
T166
Y
P
D
R
I
I
N
T
F
S
I
L
P
S
P
Site 16
S172
N
T
F
S
I
L
P
S
P
K
V
S
D
T
V
Site 17
S176
I
L
P
S
P
K
V
S
D
T
V
V
E
P
Y
Site 18
T178
P
S
P
K
V
S
D
T
V
V
E
P
Y
N
A
Site 19
Y183
S
D
T
V
V
E
P
Y
N
A
T
L
S
V
H
Site 20
S188
E
P
Y
N
A
T
L
S
V
H
Q
L
I
E
N
Site 21
T199
L
I
E
N
A
D
E
T
F
C
I
D
N
E
A
Site 22
S212
E
A
L
Y
D
I
C
S
K
T
L
K
L
P
T
Site 23
T214
L
Y
D
I
C
S
K
T
L
K
L
P
T
P
T
Site 24
T219
S
K
T
L
K
L
P
T
P
T
Y
G
D
L
N
Site 25
Y222
L
K
L
P
T
P
T
Y
G
D
L
N
H
L
V
Site 26
T274
M
P
G
F
A
P
L
T
S
R
G
S
Q
Q
Y
Site 27
S275
P
G
F
A
P
L
T
S
R
G
S
Q
Q
Y
R
Site 28
S278
A
P
L
T
S
R
G
S
Q
Q
Y
R
A
L
T
Site 29
Y281
T
S
R
G
S
Q
Q
Y
R
A
L
T
V
A
E
Site 30
T285
S
Q
Q
Y
R
A
L
T
V
A
E
L
T
Q
Q
Site 31
T312
P
R
H
G
R
Y
L
T
A
A
A
I
F
R
G
Site 32
S339
N
I
Q
D
K
N
S
S
Y
F
A
D
W
L
P
Site 33
Y340
I
Q
D
K
N
S
S
Y
F
A
D
W
L
P
N
Site 34
S364
P
P
R
G
L
K
M
S
A
T
F
I
G
N
N
Site 35
T366
R
G
L
K
M
S
A
T
F
I
G
N
N
T
A
Site 36
S382
Q
E
L
F
K
R
V
S
E
Q
F
T
A
M
F
Site 37
Y398
R
K
A
F
L
H
W
Y
T
G
E
G
M
D
E
Site 38
Y422
M
N
D
L
V
S
E
Y
Q
Q
Y
Q
D
A
T
Site 39
Y425
L
V
S
E
Y
Q
Q
Y
Q
D
A
T
A
E
E
Site 40
Y438
E
E
E
E
D
E
E
Y
A
E
E
E
V
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation