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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF568
Full Name:
Zinc finger protein 568
Alias:
Zinc finger 568; Zn568
Type:
Intracellular, Nucleus protein
Mass (Da):
74369
Number AA:
644
UniProt ID:
Q3ZCX4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
T
S
Q
S
S
V
I
S
N
S
C
V
T
M
E
Site 2
S29
M
E
R
K
A
W
C
S
Q
E
S
A
L
S
E
Site 3
S35
C
S
Q
E
S
A
L
S
E
E
E
E
D
T
T
Site 4
T41
L
S
E
E
E
E
D
T
T
R
P
L
E
T
V
Site 5
T42
S
E
E
E
E
D
T
T
R
P
L
E
T
V
T
Site 6
T49
T
R
P
L
E
T
V
T
F
K
D
V
A
V
D
Site 7
T58
K
D
V
A
V
D
L
T
Q
E
E
W
E
Q
M
Site 8
Y73
K
P
A
Q
R
N
L
Y
R
D
V
M
L
E
N
Site 9
T86
E
N
Y
S
N
L
V
T
V
G
C
Q
V
T
K
Site 10
T134
Q
I
K
K
Q
Q
E
T
L
V
R
K
V
T
S
Site 11
S166
A
K
I
F
P
L
S
S
D
I
V
T
S
R
Q
Site 12
T170
P
L
S
S
D
I
V
T
S
R
Q
S
F
Y
D
Site 13
S171
L
S
S
D
I
V
T
S
R
Q
S
F
Y
D
C
Site 14
S174
D
I
V
T
S
R
Q
S
F
Y
D
C
D
S
L
Site 15
Y176
V
T
S
R
Q
S
F
Y
D
C
D
S
L
D
K
Site 16
S180
Q
S
F
Y
D
C
D
S
L
D
K
G
L
E
H
Site 17
Y212
N
E
F
G
K
P
F
Y
H
C
A
S
Y
V
V
Site 18
Y250
I
H
A
G
E
K
P
Y
E
C
K
E
C
G
K
Site 19
T267
S
R
K
E
N
L
I
T
H
Q
K
I
H
T
G
Site 20
T273
I
T
H
Q
K
I
H
T
G
E
K
P
Y
K
C
Site 21
Y278
I
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 22
T301
I
R
H
H
R
I
H
T
G
E
K
P
Y
A
C
Site 23
S316
K
D
C
W
K
A
F
S
Q
K
S
N
L
I
E
Site 24
S319
W
K
A
F
S
Q
K
S
N
L
I
E
H
E
R
Site 25
T329
I
E
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 26
Y334
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 27
S342
E
C
K
E
C
G
K
S
F
S
Q
K
Q
N
L
Site 28
S344
K
E
C
G
K
S
F
S
Q
K
Q
N
L
I
E
Site 29
T357
I
E
H
E
K
I
H
T
G
E
K
P
Y
A
C
Site 30
Y362
I
H
T
G
E
K
P
Y
A
C
N
E
C
G
R
Site 31
S372
N
E
C
G
R
A
F
S
R
M
S
S
V
T
L
Site 32
S375
G
R
A
F
S
R
M
S
S
V
T
L
H
M
R
Site 33
S376
R
A
F
S
R
M
S
S
V
T
L
H
M
R
S
Site 34
T378
F
S
R
M
S
S
V
T
L
H
M
R
S
H
T
Site 35
S383
S
V
T
L
H
M
R
S
H
T
G
E
K
P
Y
Site 36
T385
T
L
H
M
R
S
H
T
G
E
K
P
Y
K
C
Site 37
Y390
S
H
T
G
E
K
P
Y
K
C
N
K
C
G
K
Site 38
T413
I
I
H
M
R
S
H
T
G
E
K
P
Y
V
C
Site 39
Y418
S
H
T
G
E
K
P
Y
V
C
S
E
C
G
K
Site 40
S421
G
E
K
P
Y
V
C
S
E
C
G
K
A
F
S
Site 41
S428
S
E
C
G
K
A
F
S
Q
S
S
S
L
T
V
Site 42
S430
C
G
K
A
F
S
Q
S
S
S
L
T
V
H
M
Site 43
S432
K
A
F
S
Q
S
S
S
L
T
V
H
M
R
N
Site 44
T434
F
S
Q
S
S
S
L
T
V
H
M
R
N
H
T
Site 45
T441
T
V
H
M
R
N
H
T
A
E
K
P
Y
E
C
Site 46
Y446
N
H
T
A
E
K
P
Y
E
C
K
E
C
G
K
Site 47
T469
I
T
H
Q
K
I
H
T
G
E
K
P
Y
E
C
Site 48
Y474
I
H
T
G
E
K
P
Y
E
C
S
E
C
G
K
Site 49
T497
I
R
H
Q
R
I
H
T
G
E
K
P
Y
A
C
Site 50
T505
G
E
K
P
Y
A
C
T
V
C
G
K
A
F
S
Site 51
S512
T
V
C
G
K
A
F
S
Q
K
S
N
L
T
E
Site 52
S515
G
K
A
F
S
Q
K
S
N
L
T
E
H
E
K
Site 53
T525
T
E
H
E
K
I
H
T
G
E
K
P
Y
H
C
Site 54
Y530
I
H
T
G
E
K
P
Y
H
C
N
Q
C
G
K
Site 55
S540
N
Q
C
G
K
A
F
S
Q
R
Q
N
L
L
E
Site 56
T553
L
E
H
E
K
I
H
T
G
E
K
P
F
K
C
Site 57
S568
N
E
C
G
K
A
F
S
R
I
S
S
L
T
L
Site 58
S571
G
K
A
F
S
R
I
S
S
L
T
L
H
V
R
Site 59
S572
K
A
F
S
R
I
S
S
L
T
L
H
V
R
S
Site 60
T574
F
S
R
I
S
S
L
T
L
H
V
R
S
H
T
Site 61
S579
S
L
T
L
H
V
R
S
H
T
G
E
K
P
Y
Site 62
T581
T
L
H
V
R
S
H
T
G
E
K
P
Y
E
C
Site 63
Y586
S
H
T
G
E
K
P
Y
E
C
N
K
C
G
K
Site 64
S596
N
K
C
G
K
A
F
S
Q
C
S
L
L
I
I
Site 65
S599
G
K
A
F
S
Q
C
S
L
L
I
I
H
M
R
Site 66
T609
I
I
H
M
R
S
H
T
G
E
K
P
F
E
C
Site 67
S624
N
E
C
G
K
A
F
S
Q
R
A
S
L
S
I
Site 68
S628
K
A
F
S
Q
R
A
S
L
S
I
H
K
R
G
Site 69
S630
F
S
Q
R
A
S
L
S
I
H
K
R
G
H
T
Site 70
T637
S
I
H
K
R
G
H
T
G
E
R
H
Q
V
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation