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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARP15
Full Name:
Poly [ADP-ribose] polymerase 15
Alias:
B-aggressive lymphoma protein 3
Type:
Mass (Da):
72541
Number AA:
656
UniProt ID:
Q460N3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
G
R
D
R
E
A
G
S
M
L
P
A
G
N
R
Site 2
S32
N
R
G
A
R
K
A
S
R
R
S
S
S
R
S
Site 3
S35
A
R
K
A
S
R
R
S
S
S
R
S
M
S
R
Site 4
S36
R
K
A
S
R
R
S
S
S
R
S
M
S
R
D
Site 5
S37
K
A
S
R
R
S
S
S
R
S
M
S
R
D
N
Site 6
S39
S
R
R
S
S
S
R
S
M
S
R
D
N
K
F
Site 7
S41
R
S
S
S
R
S
M
S
R
D
N
K
F
S
K
Site 8
S47
M
S
R
D
N
K
F
S
K
K
D
C
L
S
I
Site 9
S53
F
S
K
K
D
C
L
S
I
R
N
V
V
A
S
Site 10
S60
S
I
R
N
V
V
A
S
I
Q
T
K
E
G
L
Site 11
S100
Q
L
G
G
G
P
L
S
R
A
F
L
Q
K
A
Site 12
T122
L
D
D
R
R
R
E
T
E
E
K
V
G
N
I
Site 13
Y208
I
L
S
E
V
F
E
Y
S
S
S
T
R
P
I
Site 14
S211
E
V
F
E
Y
S
S
S
T
R
P
I
T
S
P
Site 15
T216
S
S
S
T
R
P
I
T
S
P
L
Q
E
V
H
Site 16
S217
S
S
T
R
P
I
T
S
P
L
Q
E
V
H
F
Site 17
Y227
Q
E
V
H
F
L
V
Y
T
N
D
D
E
G
C
Site 18
T228
E
V
H
F
L
V
Y
T
N
D
D
E
G
C
Q
Site 19
T306
I
V
N
S
T
A
R
T
F
N
R
K
S
G
V
Site 20
S311
A
R
T
F
N
R
K
S
G
V
S
R
A
I
L
Site 21
S314
F
N
R
K
S
G
V
S
R
A
I
L
E
G
A
Site 22
T365
G
G
K
D
V
R
K
T
V
T
S
V
L
E
E
Site 23
S368
D
V
R
K
T
V
T
S
V
L
E
E
C
E
Q
Site 24
Y378
E
E
C
E
Q
R
K
Y
T
S
V
S
L
P
A
Site 25
T379
E
C
E
Q
R
K
Y
T
S
V
S
L
P
A
I
Site 26
S382
Q
R
K
Y
T
S
V
S
L
P
A
I
G
T
G
Site 27
T397
N
A
G
K
N
P
I
T
V
A
D
N
I
I
D
Site 28
S410
I
D
A
I
V
D
F
S
S
Q
H
S
T
P
S
Site 29
S411
D
A
I
V
D
F
S
S
Q
H
S
T
P
S
L
Site 30
S414
V
D
F
S
S
Q
H
S
T
P
S
L
K
T
V
Site 31
T415
D
F
S
S
Q
H
S
T
P
S
L
K
T
V
K
Site 32
S417
S
S
Q
H
S
T
P
S
L
K
T
V
K
V
V
Site 33
Y435
P
E
L
L
N
I
F
Y
D
S
M
K
K
R
D
Site 34
S444
S
M
K
K
R
D
L
S
A
S
L
N
F
Q
S
Site 35
S446
K
K
R
D
L
S
A
S
L
N
F
Q
S
T
F
Site 36
T452
A
S
L
N
F
Q
S
T
F
S
M
T
T
C
N
Site 37
S482
V
Q
L
E
P
G
Q
S
E
Y
N
T
I
K
D
Site 38
T486
P
G
Q
S
E
Y
N
T
I
K
D
K
F
T
R
Site 39
T492
N
T
I
K
D
K
F
T
R
T
C
S
S
Y
A
Site 40
S496
D
K
F
T
R
T
C
S
S
Y
A
I
E
K
I
Site 41
Y498
F
T
R
T
C
S
S
Y
A
I
E
K
I
E
R
Site 42
T539
E
R
L
L
F
H
G
T
D
A
D
S
V
P
Y
Site 43
Y546
T
D
A
D
S
V
P
Y
V
N
Q
H
G
F
N
Site 44
Y564
A
G
K
N
A
V
S
Y
G
K
G
T
Y
F
A
Site 45
Y569
V
S
Y
G
K
G
T
Y
F
A
V
D
A
S
Y
Site 46
Y576
Y
F
A
V
D
A
S
Y
S
A
K
D
T
Y
S
Site 47
T581
A
S
Y
S
A
K
D
T
Y
S
K
P
D
S
N
Site 48
Y582
S
Y
S
A
K
D
T
Y
S
K
P
D
S
N
G
Site 49
S583
Y
S
A
K
D
T
Y
S
K
P
D
S
N
G
R
Site 50
S587
D
T
Y
S
K
P
D
S
N
G
R
K
H
M
Y
Site 51
Y594
S
N
G
R
K
H
M
Y
V
V
R
V
L
T
G
Site 52
T612
K
G
R
A
G
L
V
T
P
P
P
K
N
P
H
Site 53
S627
N
P
T
D
L
F
D
S
V
T
N
N
T
R
S
Site 54
T629
T
D
L
F
D
S
V
T
N
N
T
R
S
P
K
Site 55
T632
F
D
S
V
T
N
N
T
R
S
P
K
L
F
V
Site 56
S634
S
V
T
N
N
T
R
S
P
K
L
F
V
V
F
Site 57
Y650
D
N
Q
A
Y
P
E
Y
L
I
T
F
T
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation