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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF404
Full Name:
Zinc finger protein 404
Alias:
Type:
Mass (Da):
65455
Number AA:
552
UniProt ID:
Q494X3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
S
D
V
A
I
D
F
S
Q
E
E
W
E
Y
L
Site 2
Y22
F
S
Q
E
E
W
E
Y
L
N
S
D
Q
R
D
Site 3
S25
E
E
W
E
Y
L
N
S
D
Q
R
D
L
Y
R
Site 4
Y31
N
S
D
Q
R
D
L
Y
R
D
V
M
L
E
N
Site 5
Y39
R
D
V
M
L
E
N
Y
T
N
L
V
S
L
D
Site 6
T51
S
L
D
F
N
F
T
T
E
S
N
K
L
S
S
Site 7
S53
D
F
N
F
T
T
E
S
N
K
L
S
S
E
K
Site 8
S57
T
T
E
S
N
K
L
S
S
E
K
R
N
Y
E
Site 9
S58
T
E
S
N
K
L
S
S
E
K
R
N
Y
E
V
Site 10
Y63
L
S
S
E
K
R
N
Y
E
V
N
A
Y
H
Q
Site 11
Y68
R
N
Y
E
V
N
A
Y
H
Q
E
T
W
K
R
Site 12
T88
L
M
R
F
I
F
R
T
D
P
Q
Y
T
I
E
Site 13
Y92
I
F
R
T
D
P
Q
Y
T
I
E
F
G
R
Q
Site 14
S117
M
I
F
K
K
H
K
S
L
P
L
H
K
R
N
Site 15
T126
P
L
H
K
R
N
N
T
R
E
K
S
Y
E
C
Site 16
S130
R
N
N
T
R
E
K
S
Y
E
C
K
E
Y
K
Site 17
Y136
K
S
Y
E
C
K
E
Y
K
K
G
F
R
K
Y
Site 18
Y143
Y
K
K
G
F
R
K
Y
L
H
L
T
E
H
L
Site 19
T154
T
E
H
L
R
D
H
T
G
V
I
P
Y
E
C
Site 20
Y159
D
H
T
G
V
I
P
Y
E
C
N
E
C
G
K
Site 21
Y187
I
H
T
D
L
K
P
Y
E
C
N
G
C
E
K
Site 22
Y199
C
E
K
A
F
R
F
Y
S
Q
L
I
Q
H
Q
Site 23
S200
E
K
A
F
R
F
Y
S
Q
L
I
Q
H
Q
I
Site 24
Y215
I
H
T
G
M
K
P
Y
E
C
K
Q
C
G
K
Site 25
S228
G
K
A
F
R
R
H
S
H
L
T
E
H
Q
K
Site 26
Y271
I
H
H
G
V
K
P
Y
K
C
K
E
C
G
K
Site 27
S284
G
K
A
F
G
H
R
S
S
L
Y
Q
H
K
K
Site 28
S285
K
A
F
G
H
R
S
S
L
Y
Q
H
K
K
I
Site 29
Y287
F
G
H
R
S
S
L
Y
Q
H
K
K
I
H
S
Site 30
Y312
E
K
A
F
V
R
S
Y
L
L
V
E
H
Q
R
Site 31
S320
L
L
V
E
H
Q
R
S
H
T
G
E
K
P
H
Site 32
T322
V
E
H
Q
R
S
H
T
G
E
K
P
H
E
C
Site 33
S337
M
E
C
G
K
A
F
S
K
G
S
S
L
L
K
Site 34
S341
K
A
F
S
K
G
S
S
L
L
K
H
K
R
I
Site 35
S350
L
K
H
K
R
I
H
S
S
E
K
L
Y
D
C
Site 36
Y355
I
H
S
S
E
K
L
Y
D
C
K
D
C
G
K
Site 37
S368
G
K
A
F
C
R
G
S
Q
L
T
Q
H
Q
R
Site 38
T378
T
Q
H
Q
R
I
H
T
G
E
K
P
H
E
C
Site 39
Y397
K
T
F
K
L
H
S
Y
L
I
Q
H
Q
I
I
Site 40
Y411
I
H
T
D
L
K
P
Y
E
C
K
Q
C
G
K
Site 41
S421
K
Q
C
G
K
A
F
S
R
V
G
D
L
K
T
Site 42
T428
S
R
V
G
D
L
K
T
H
Q
S
I
H
A
G
Site 43
Y439
I
H
A
G
E
K
P
Y
E
C
K
E
C
G
K
Site 44
T447
E
C
K
E
C
G
K
T
F
R
L
N
S
Q
L
Site 45
S452
G
K
T
F
R
L
N
S
Q
L
I
Y
H
Q
T
Site 46
Y456
R
L
N
S
Q
L
I
Y
H
Q
T
I
H
T
G
Site 47
T459
S
Q
L
I
Y
H
Q
T
I
H
T
G
L
K
P
Site 48
Y467
I
H
T
G
L
K
P
Y
V
C
K
E
C
K
K
Site 49
S478
E
C
K
K
A
F
R
S
I
S
G
L
S
Q
H
Site 50
S480
K
K
A
F
R
S
I
S
G
L
S
Q
H
K
R
Site 51
S483
F
R
S
I
S
G
L
S
Q
H
K
R
I
H
T
Site 52
T490
S
Q
H
K
R
I
H
T
G
E
K
P
Y
E
C
Site 53
S507
C
D
K
A
F
N
R
S
D
R
L
T
Q
H
E
Site 54
T511
F
N
R
S
D
R
L
T
Q
H
E
T
I
H
T
Site 55
T518
T
Q
H
E
T
I
H
T
G
V
K
P
Q
K
C
Site 56
Y536
G
K
A
F
S
H
C
Y
Q
L
S
Q
H
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation