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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRIM60
Full Name:
Tripartite motif-containing protein 60
Alias:
RING finger protein 129;RING finger protein 33
Type:
Mass (Da):
55114
Number AA:
471
UniProt ID:
Q495X7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
V
N
L
Q
E
E
S
S
C
P
I
C
L
E
Y
Site 2
S43
C
R
S
C
L
S
V
S
W
K
D
L
D
D
T
Site 3
Y62
V
C
R
F
C
F
P
Y
K
S
F
R
R
N
P
Site 4
T75
N
P
Q
L
R
N
L
T
E
I
A
K
Q
L
Q
Site 5
S86
K
Q
L
Q
I
R
R
S
K
R
K
R
Q
K
E
Site 6
T105
E
K
H
N
Q
F
L
T
L
F
C
V
K
D
L
Site 7
T117
K
D
L
E
I
L
C
T
Q
C
S
F
S
T
K
Site 8
Y129
S
T
K
H
Q
K
H
Y
I
C
P
I
K
K
A
Site 9
S138
C
P
I
K
K
A
A
S
Y
H
R
E
I
L
E
Site 10
Y139
P
I
K
K
A
A
S
Y
H
R
E
I
L
E
G
Site 11
S147
H
R
E
I
L
E
G
S
L
E
P
L
R
N
N
Site 12
S169
I
I
L
Q
G
S
K
S
V
E
L
K
K
K
V
Site 13
Y178
E
L
K
K
K
V
E
Y
K
R
E
E
I
N
S
Site 14
S185
Y
K
R
E
E
I
N
S
E
F
E
Q
I
R
L
Site 15
S224
N
E
N
L
V
E
L
S
D
Y
V
S
T
L
K
Site 16
S228
V
E
L
S
D
Y
V
S
T
L
K
H
L
L
R
Site 17
S241
L
R
E
V
E
G
K
S
V
Q
S
N
L
E
L
Site 18
T250
Q
S
N
L
E
L
L
T
Q
A
K
S
M
H
H
Site 19
Y259
A
K
S
M
H
H
K
Y
Q
N
L
K
C
P
E
Site 20
S269
L
K
C
P
E
L
F
S
F
R
L
T
K
Y
G
Site 21
Y275
F
S
F
R
L
T
K
Y
G
F
S
L
P
P
Q
Site 22
S278
R
L
T
K
Y
G
F
S
L
P
P
Q
Y
S
G
Site 23
Y283
G
F
S
L
P
P
Q
Y
S
G
L
D
R
I
I
Site 24
S284
F
S
L
P
P
Q
Y
S
G
L
D
R
I
I
K
Site 25
S311
A
H
P
Q
L
L
V
S
E
D
R
K
A
V
R
Site 26
Y319
E
D
R
K
A
V
R
Y
E
R
K
K
R
N
I
Site 27
Y328
R
K
K
R
N
I
C
Y
D
P
R
R
F
Y
V
Site 28
S342
V
C
P
A
V
L
G
S
Q
R
F
S
S
G
R
Site 29
S346
V
L
G
S
Q
R
F
S
S
G
R
H
Y
W
E
Site 30
S347
L
G
S
Q
R
F
S
S
G
R
H
Y
W
E
V
Site 31
Y351
R
F
S
S
G
R
H
Y
W
E
V
E
V
G
N
Site 32
S394
A
I
G
R
Y
M
K
S
G
Y
V
A
S
G
P
Site 33
Y396
G
R
Y
M
K
S
G
Y
V
A
S
G
P
K
T
Site 34
S399
M
K
S
G
Y
V
A
S
G
P
K
T
T
Q
L
Site 35
Y429
E
L
G
D
L
S
F
Y
N
M
N
D
R
S
I
Site 36
Y451
F
T
E
A
V
W
P
Y
F
Y
T
G
T
D
S
Site 37
T454
A
V
W
P
Y
F
Y
T
G
T
D
S
E
P
L
Site 38
S458
Y
F
Y
T
G
T
D
S
E
P
L
K
I
C
S
Site 39
S465
S
E
P
L
K
I
C
S
V
S
D
S
E
R
_
Site 40
S467
P
L
K
I
C
S
V
S
D
S
E
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation