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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CERKL
Full Name:
Ceramide kinase-like protein
Alias:
Type:
Mass (Da):
62622
Number AA:
558
UniProt ID:
Q49MI3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
R
R
R
R
N
R
V
S
A
L
E
G
G
R
E
Site 2
S35
V
P
P
A
L
L
T
S
P
Q
Q
T
E
A
A
Site 3
S64
D
S
C
D
V
V
L
S
E
R
A
L
R
W
R
Site 4
S82
P
E
R
P
A
G
D
S
K
Y
D
L
L
C
K
Site 5
Y84
R
P
A
G
D
S
K
Y
D
L
L
C
K
E
E
Site 6
S100
I
E
L
K
D
I
F
S
V
K
L
K
R
R
C
Site 7
S108
V
K
L
K
R
R
C
S
V
K
Q
Q
R
S
G
Site 8
S168
G
F
P
N
R
P
K
S
L
K
I
L
L
N
P
Site 9
S177
K
I
L
L
N
P
Q
S
H
K
K
E
A
T
Q
Site 10
Y186
K
K
E
A
T
Q
V
Y
Y
E
K
V
E
P
L
Site 11
Y187
K
E
A
T
Q
V
Y
Y
E
K
V
E
P
L
L
Site 12
T204
A
G
I
K
T
D
V
T
I
M
E
Y
E
G
H
Site 13
S214
E
Y
E
G
H
A
L
S
L
L
K
E
C
E
L
Site 14
T244
W
S
V
Q
R
L
F
T
G
M
Q
T
L
E
P
Site 15
T286
M
E
T
D
R
I
L
T
P
V
R
A
Q
L
P
Site 16
T337
V
D
V
C
T
F
S
T
A
G
K
L
L
R
F
Site 17
S347
K
L
L
R
F
G
F
S
A
M
F
G
F
G
G
Site 18
Y363
T
L
A
L
A
E
K
Y
R
W
M
S
P
N
Q
Site 19
S367
A
E
K
Y
R
W
M
S
P
N
Q
R
R
D
F
Site 20
S391
K
A
E
D
C
E
I
S
F
L
P
F
N
S
S
Site 21
S397
I
S
F
L
P
F
N
S
S
D
D
V
Q
E
R
Site 22
S398
S
F
L
P
F
N
S
S
D
D
V
Q
E
R
R
Site 23
S409
Q
E
R
R
A
Q
G
S
P
K
S
D
C
N
D
Site 24
S412
R
A
Q
G
S
P
K
S
D
C
N
D
Q
W
Q
Site 25
T448
P
R
G
L
A
P
N
T
R
L
N
N
G
S
M
Site 26
S454
N
T
R
L
N
N
G
S
M
A
L
I
I
A
R
Site 27
T463
A
L
I
I
A
R
N
T
S
R
P
E
F
I
K
Site 28
S464
L
I
I
A
R
N
T
S
R
P
E
F
I
K
H
Site 29
Y475
F
I
K
H
L
K
R
Y
A
S
V
K
N
Q
F
Site 30
S477
K
H
L
K
R
Y
A
S
V
K
N
Q
F
N
F
Site 31
T491
F
P
F
V
E
T
Y
T
V
E
E
V
K
V
H
Site 32
T503
K
V
H
P
R
N
N
T
G
G
Y
N
P
E
E
Site 33
T515
P
E
E
E
E
D
E
T
A
S
E
N
C
F
P
Site 34
S546
R
L
H
P
R
L
I
S
L
Y
G
G
S
M
E
Site 35
Y548
H
P
R
L
I
S
L
Y
G
G
S
M
E
E
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation