PhosphoNET

           
Protein Info 
   
Short Name:  HYDIN
Full Name:  Hydrocephalus-inducing protein homolog
Alias: 
Type: 
Mass (Da):  575817
Number AA:  5120
UniProt ID:  Q4G0P3
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9TSRRLEESMGAVQMG
Site 2S26NMFKGFQSKVLPPLS
Site 3S33SKVLPPLSPKVVTEE
Site 4T47EEVNRMLTPSEFLKE
Site 5S49VNRMLTPSEFLKEMS
Site 6T58FLKEMSLTTEQRLAK
Site 7Y110SEIIFQNYTPCEVYE
Site 8T111EIIFQNYTPCEVYEV
Site 9Y141VVEESSPYFKVISPK
Site 10S146SPYFKVISPKDIGHK
Site 11T167SIFRILFTPEENKDY
Site 12Y174TPEENKDYAHTLTCV
Site 13T177ENKDYAHTLTCVTER
Site 14T179KDYAHTLTCVTEREK
Site 15S209FPDKLNFSTCPVKYS
Site 16T210PDKLNFSTCPVKYST
Site 17S255GTLNVGESMQLEVEF
Site 18S266EVEFEPQSVGDHSGR
Site 19S271PQSVGDHSGRLIVCY
Site 20S303NIRLDKNSLTIEKTY
Site 21T305RLDKNSLTIEKTYIS
Site 22T309NSLTIEKTYISLANQ
Site 23S312TIEKTYISLANQRTI
Site 24T320LANQRTITIHNRSNI
Site 25Y347QEEDREKYRACDDLI
Site 26T361IKEEKDETDEFFEEC
Site 27T370EFFEECITDPLLREH
Site 28S379PLLREHLSVLSRTFA
Site 29T384HLSVLSRTFANQRRL
Site 30S396RRLVQGDSKLFFNNV
Site 31S417EGDVWPNSSAEITVY
Site 32T422PNSSAEITVYFNPLE
Site 33Y424SSAEITVYFNPLEAK
Site 34Y433NPLEAKLYQQTIYCD
Site 35Y438KLYQQTIYCDILGRE
Site 36Y481FTGSAHCYEAILYNK
Site 37Y486HCYEAILYNKGSIDA
Site 38Y599TSLIPMTYKLRIPGD
Site 39S612GDGLGHKSISYCEQH
Site 40S614GLGHKSISYCEQHVD
Site 41Y615LGHKSISYCEQHVDY
Site 42Y622YCEQHVDYKRPSWTK
Site 43S626HVDYKRPSWTKEEIS
Site 44S634WTKEEISSMKPKEFT
Site 45S643KPKEFTISPDCGTIR
Site 46T648TISPDCGTIRPQGFA
Site 47S663AIRVTLCSNTVQKYE
Site 48Y714FGHCFLKYPYEKTLQ
Site 49T719LKYPYEKTLQLANQD
Site 50S753LFSSPTPSGVISPSS
Site 51T773LVLETQVTGEHRSTV
Site 52S778QVTGEHRSTVYISIF
Site 53Y781GEHRSTVYISIFGSQ
Site 54S783HRSTVYISIFGSQDP
Site 55Y806AGEGPVIYVHPNQVD
Site 56Y818QVDFGNIYVLKDSSR
Site 57T892LDIENSSTYRIPVQA
Site 58Y893DIENSSTYRIPVQAS
Site 59S904VQASGTGSTIVSDKP
Site 60S908GTGSTIVSDKPFAPE
Site 61T926GAHFSLDTHYYHFKL
Site 62Y928HFSLDTHYYHFKLIN
Site 63Y929FSLDTHYYHFKLINK
Site 64S957FRPQAKLSKKGRVKK
Site 65S974AHVQPQPSGSQEPRD
Site 66S976VQPQPSGSQEPRDPQ
Site 67S984QEPRDPQSPVFHLHP
Site 68S993VFHLHPASMELYPGQ
Site 69Y997HPASMELYPGQAIDV
Site 70T1012ILEGYSATPRIVKEK
Site 71S1066RLEKKPNSILKPDYQ
Site 72Y1072NSILKPDYQPLAIKN
Site 73S1103FICETDKSLLPATPE
Site 74T1108DKSLLPATPEPIKLE
Site 75S1129LLIKFDPSYRNDLNN
Site 76Y1130LIKFDPSYRNDLNNW
Site 77Y1147EEILAIKYVEHPQID
Site 78S1155VEHPQIDSLDLRGEV
Site 79Y1164DLRGEVHYPNLSFET
Site 80S1168EVHYPNLSFETKELD
Site 81Y1188NDTELIRYVTITNCS
Site 82T1218ENQIRFVTLPKKPYS
Site 83Y1224VTLPKKPYSAPVSQM
Site 84S1225TLPKKPYSAPVSQME
Site 85S1229KPYSAPVSQMESIPA
Site 86S1233APVSQMESIPATSEA
Site 87T1237QMESIPATSEAASPP
Site 88S1238MESIPATSEAASPPA
Site 89T1280EEKELRKTKASSVIS
Site 90S1283ELRKTKASSVISDVR
Site 91S1287TKASSVISDVRCPFH
Site 92Y1300FHGEERIYSSQSQVE
Site 93S1301HGEERIYSSQSQVED
Site 94S1302GEERIYSSQSQVEDQ
Site 95S1304ERIYSSQSQVEDQES
Site 96S1311SQVEDQESLQTCEQN
Site 97T1314EDQESLQTCEQNEML
Site 98S1342FGVLQPHSSHQISFT
Site 99S1343GVLQPHSSHQISFTF
Site 100S1347PHSSHQISFTFYGHA
Site 101T1349SSHQISFTFYGHANI
Site 102T1371CEVEEGPTYEITLKG
Site 103Y1372EVEEGPTYEITLKGE
Site 104Y1385GEASLVNYSFDTKDI
Site 105S1386EASLVNYSFDTKDIH
Site 106Y1394FDTKDIHYGLQLFDH
Site 107T1403LQLFDHVTEREITLT
Site 108T1408HVTEREITLTNMGKV
Site 109T1410TEREITLTNMGKVGF
Site 110T1423GFEFKVLTDHQSSPD
Site 111S1427KVLTDHQSSPDNLLP
Site 112S1428VLTDHQSSPDNLLPG
Site 113S1448PVSGFISSHQEQVLK
Site 114Y1457QEQVLKVYYLPGVPE
Site 115S1469VPEVFKRSFQIQIAH
Site 116T1483HLDPENITLSGEGIF
Site 117S1485DPENITLSGEGIFPQ
Site 118T1502LDLPRNLTANEKYEM
Site 119T1518LNQARKNTDKEYNKC
Site 120Y1522RKNTDKEYNKCEMLD
Site 121T1535LDHFDIITEEVPEDE
Site 122S1561VERLIVQSYVLEHQK
Site 123Y1562ERLIVQSYVLEHQKT
Site 124T1569YVLEHQKTTTPDPMD
Site 125T1571LEHQKTTTPDPMDDP
Site 126S1581PMDDPCFSHRSRRKL
Site 127S1584DPCFSHRSRRKLAKI
Site 128S1624NTSHFPVSFHADKRV
Site 129T1635DKRVLHETGFSTELD
Site 130Y1750LEKHMPKYLRQKLRA
Site 131T1763RAELKPKTRIFEIQP
Site 132Y1795MPKEEKFYSQTLVFQ
Site 133S1796PKEEKFYSQTLVFQI
Site 134S1826LEPRLEFSPSVLDLG
Site 135Y1867SLEFDQQYLIEEKIL
Site 136Y1880ILRKLKGYDSYNTLL
Site 137S1882RKLKGYDSYNTLLLP
Site 138Y1883KLKGYDSYNTLLLPP
Site 139T1885KGYDSYNTLLLPPRN
Site 140Y1902EKLPPELYEYFKEIK
Site 141Y1904LPPELYEYFKEIKKS
Site 142S1911YFKEIKKSKEEQMRA
Site 143Y1920EEQMRAKYLENLAQE
Site 144T1934ENEEEDITSSDQGTS
Site 145S1935NEEEDITSSDQGTSN
Site 146S1936EEEDITSSDQGTSNS
Site 147T1940ITSSDQGTSNSTKRT
Site 148S1941TSSDQGTSNSTKRTS
Site 149S1943SDQGTSNSTKRTSLS
Site 150T1944DQGTSNSTKRTSLSR
Site 151T1947TSNSTKRTSLSRGIS
Site 152S1948SNSTKRTSLSRGISV
Site 153S1950STKRTSLSRGISVTS
Site 154S1954TSLSRGISVTSNLEE
Site 155T1956LSRGISVTSNLEEWH
Site 156T1971ALLVESKTYLEEEED
Site 157Y1972LLVESKTYLEEEEDE
Site 158S1981EEEEDEESLEKIIFQ
Site 159S1997DKLQSIDSHSMEEVG
Site 160S1999LQSIDSHSMEEVGEV
Site 161S2012EVENNPVSKAIARHL
Site 162S2024RHLGIDISAEGRLAK
Site 163S2054GKSANAVSVAKYYNA
Site 164S2097IRAAIEQSVKEGEEA
Site 165S2121VIGQGRLSTDTLGKL
Site 166T2122IGQGRLSTDTLGKLA
Site 167T2124QGRLSTDTLGKLASE
Site 168S2144PEIKPGKSVRGSVVI
Site 169S2148PGKSVRGSVVITKSK
Site 170T2152VRGSVVITKSKADSH
Site 171S2154GSVVITKSKADSHGS
Site 172S2158ITKSKADSHGSGSQK
Site 173S2161SKADSHGSGSQKQHH
Site 174S2163ADSHGSGSQKQHHSH
Site 175S2169GSQKQHHSHQSETPQ
Site 176S2172KQHHSHQSETPQISS
Site 177T2174HHSHQSETPQISSSP
Site 178S2178QSETPQISSSPLPPG
Site 179S2179SETPQISSSPLPPGP
Site 180S2180ETPQISSSPLPPGPI
Site 181S2192GPIHRWLSVSPSVGG
Site 182S2194IHRWLSVSPSVGGET
Site 183S2196RWLSVSPSVGGETGL
Site 184Y2227RIQLSDCYRGVVFDG
Site 185Y2261IGSREHIYILNMAQD
Site 186Y2269ILNMAQDYAAMKAQE
Site 187T2310EEEYDALTEEEKLTF
Site 188T2316LTEEEKLTFDRGIQQ
Site 189S2379EEPPMKKSQAANKQV
Site 190T2390NKQVPPLTKVDVKME
Site 191S2404ETIERKISVREQTMS
Site 192T2409KISVREQTMSEKEEL
Site 193S2411SVREQTMSEKEELNK
Site 194S2427KRNMGDVSMHGLPLV
Site 195S2440LVQDQEDSEGDNSKD
Site 196S2445EDSEGDNSKDPDKQL
Site 197T2458QLAPKFKTYELTLKD
Site 198T2462KFKTYELTLKDVQNI
Site 199Y2472DVQNILMYWDRKQGV
Site 200T2520ERLEKERTEKERLER
Site 201S2579TPDFEGLSWKQALES
Site 202T2627PVKRPPLTMTDDLEH
Site 203S2646IPPSEDISLDEKKEM
Site 204S2674KAQEEQTSSSKGGKQ
Site 205S2675AQEEQTSSSKGGKQK
Site 206S2676QEEQTSSSKGGKQKM
Site 207T2714LSGEPAGTISQLSDT
Site 208S2716GEPAGTISQLSDTDL
Site 209T2721TISQLSDTDLDNFNG
Site 210S2731DNFNGQHSQEKFTRL
Site 211S2758VTLQVHFSSDEFGNF
Site 212S2759TLQVHFSSDEFGNFD
Site 213Y2792RGICTYPYICQDPKV
Site 214T2810QRKMDMKTNEVIFKK
Site 215Y2818NEVIFKKYVMSTETY
Site 216S2835GPLLCGKSRDKYKSS
Site 217Y2839CGKSRDKYKSSLFPG
Site 218S2841KSRDKYKSSLFPGNM
Site 219S2842SRDKYKSSLFPGNME
Site 220T2882TYFLEPNTMVLKPNE
Site 221S2901NVWAYPTSVGVFEDS
Site 222S2925EPAIFQLSCQGIRPE
Site 223S2952LLLHRQESRVVLLRN
Site 224S2971PVAWRITSLEHLGDD
Site 225T2980EHLGDDFTVSLMQGT
Site 226Y2999AEYGLHLYFQPTKPV
Site 227T3045YDIALDITFPKGAEG
Site 228T3062DFGIVRVTEEAKQPL
Site 229Y3077QLKNRGKYEIAFSFS
Site 230S3091SVDSVGISTPNINSM
Site 231S3097ISTPNINSMISVQPK
Site 232S3100PNINSMISVQPKKGS
Site 233S3107SVQPKKGSLTPTEKP
Site 234T3109QPKKGSLTPTEKPTN
Site 235T3111KKGSLTPTEKPTNVQ
Site 236S3165FSANAVYSKYNITPS
Site 237Y3167ANAVYSKYNITPSSV
Site 238T3170VYSKYNITPSSVINF
Site 239S3187LICGTRKSTTFTIEN
Site 240T3188ICGTRKSTTFTIENQ
Site 241T3189CGTRKSTTFTIENQG
Site 242T3191TRKSTTFTIENQGVT
Site 243Y3205TDFKFALYKLTGESP
Site 244S3211LYKLTGESPIHQKKA
Site 245S3220IHQKKAASHVRHARS
Site 246S3227SHVRHARSRESESFY
Site 247S3230RHARSRESESFYKTG
Site 248S3232ARSRESESFYKTGSS
Site 249Y3234SRESESFYKTGSSRA
Site 250T3236ESESFYKTGSSRAAK
Site 251S3238ESFYKTGSSRAAKFS
Site 252S3239SFYKTGSSRAAKFSD
Site 253S3245SSRAAKFSDTIQKEV
Site 254T3247RAAKFSDTIQKEVTT
Site 255S3273TVYPGFGSIPSGGQQ
Site 256S3276PGFGSIPSGGQQVIN
Site 257S3385AKARFKISNVGKITC
Site 258S3424PSKMCIASHSHAFAT
Site 259T3431SHSHAFATVSFTPQI
Site 260Y3442TPQIMQNYQCIFEAT
Site 261S3455ATLDGLPSTLAKSRG
Site 262T3456TLDGLPSTLAKSRGL
Site 263Y3487RPVLHNQYGNPLLLF
Site 264S3531QDELGVFSLKGRPTT
Site 265T3538SLKGRPTTAYIYITE
Site 266Y3540KGRPTTAYIYITEEN
Site 267T3544TTAYIYITEENKPHV
Site 268S3560AKKAHTASLVVSPGD
Site 269S3577EFDVVFHSQKVGRMR
Site 270Y3596LSVINNQYEETSIHM
Site 271T3613EGYEDDITLDNIHGL
Site 272S3625HGLVAPTSQEDISIS
Site 273S3630PTSQEDISISEFTEI
Site 274S3632SQEDISISEFTEIIE
Site 275Y3666DCHIGHSYNASFTVT
Site 276S3669IGHSYNASFTVTNHS
Site 277T3671HSYNASFTVTNHSQV
Site 278T3673YNASFTVTNHSQVNL
Site 279S3676SFTVTNHSQVNLIRF
Site 280T3763VPRNMPGTFTTKRKV
Site 281T3773TKRKVIETDPEPAHS
Site 282S3780TDPEPAHSVLEENYQ
Site 283S3794QELQLQISANVDFAS
Site 284Y3817RFKETLVYQTRVFEF
Site 285S3837GRVQLEFSWVSEDTS
Site 286S3840QLEFSWVSEDTSKAV
Site 287S3844SWVSEDTSKAVSFAK
Site 288S3848EDTSKAVSFAKPDHQ
Site 289S3864SAQKDQLSQGTMHTG
Site 290S3872QGTMHTGSTLDSTMD
Site 291S3876HTGSTLDSTMDHWAE
Site 292T3877TGSTLDSTMDHWAEG
Site 293S3885MDHWAEGSPQPFSVE
Site 294S3890EGSPQPFSVEPSSGI
Site 295S3911QKFKVKFSPLDIGDF
Site 296Y3958FDLKDSDYISGHQRN
Site 297S3960LKDSDYISGHQRNPE
Site 298S3971RNPELRGSSGGALDP
Site 299S3972NPELRGSSGGALDPN
Site 300T3980GGALDPNTRVIEFTT
Site 301T3997IGGKNLRTFTILNPT
Site 302T3999GKNLRTFTILNPTNS
Site 303S4019WISEEIESLQNPAAF
Site 304T4060GITESSWTFLIPEHN
Site 305S4084KTTEPLISLNKSHLN
Site 306S4088PLISLNKSHLNFSSL
Site 307S4094KSHLNFSSLLIGREA
Site 308T4104IGREARETVQIINKE
Site 309S4118EEQGFDFSFQDNSRY
Site 310S4123DFSFQDNSRYSEGFS
Site 311Y4125SFQDNSRYSEGFSNS
Site 312S4126FQDNSRYSEGFSNSL
Site 313S4130SRYSEGFSNSLLVCP
Site 314S4132YSEGFSNSLLVCPME
Site 315T4155FPIDIFFTPKQEGDV
Site 316T4178EKKVHPVTLNVKAEG
Site 317T4198EIKCKDRTGSITLLT
Site 318S4200KCKDRTGSITLLTPN
Site 319T4202KDRTGSITLLTPNQT
Site 320Y4252GSKTLLQYLEFSPID
Site 321S4260LEFSPIDSTVDVGQS
Site 322T4261EFSPIDSTVDVGQSV
Site 323S4273QSVHATLSFQPLKKC
Site 324T4344VITNKEETPMSIDCL
Site 325Y4352PMSIDCLYTNTTHLE
Site 326T4378NTLEIPITFYPRESI
Site 327Y4380LEIPITFYPRESINY
Site 328Y4387YPRESINYQELIPFE
Site 329S4399PFEINGLSQQTVEIK
Site 330T4402INGLSQQTVEIKGKG
Site 331T4438PGQVVKRTVSIMNNS
Site 332T4458FNQSILFTIPELQEP
Site 333S4500KKRVPPFSEEVFMEC
Site 334S4572KKFEPHFSISPEEGY
Site 335S4574FEPHFSISPEEGYIT
Site 336Y4579SISPEEGYITSGMEV
Site 337T4581SPEEGYITSGMEVSF
Site 338S4582PEEGYITSGMEVSFE
Site 339S4587ITSGMEVSFEVTYHP
Site 340T4591MEVSFEVTYHPTEVG
Site 341Y4592EVSFEVTYHPTEVGK
Site 342S4601PTEVGKESLCKNILC
Site 343Y4690NKPYEITYRPRTMNL
Site 344T4694EITYRPRTMNLENRK
Site 345T4705ENRKHQGTLFFPLPD
Site 346Y4718PDGTGWLYALHGTSE
Site 347T4741YREVPCKTPYTELLP
Site 348Y4743EVPCKTPYTELLPIT
Site 349S4774KPEKPDLSITMKGLD
Site 350S4787LDYIDVLSGSKKDYK
Site 351Y4793LSGSKKDYKLNFFSH
Site 352Y4821EVTNEFLYYNVSFRV
Site 353S4860LENPLPYSVTFSTEC
Site 354T4862NPLPYSVTFSTECRM
Site 355S4864LPYSVTFSTECRMPD
Site 356T4865PYSVTFSTECRMPDI
Site 357S4884QFVVPANSEGTFSFE
Site 358T4887VPANSEGTFSFEFQP
Site 359S4889ANSEGTFSFEFQPLK
Site 360T4900QPLKAGETFGRLTLH
Site 361T4905GETFGRLTLHNTDLG
Site 362T4909GRLTLHNTDLGYYQY
Site 363Y4913LHNTDLGYYQYELYL
Site 364Y4919GYYQYELYLKATPAL
Site 365T4923YELYLKATPALPEKP
Site 366T4935EKPVHFQTVLGSSQI
Site 367Y4950ILVKFINYTRQRTEY
Site 368Y4957YTRQRTEYYCRTDCT
Site 369Y4958TRQRTEYYCRTDCTD
Site 370S4985GQGGTEASVEVLFEP
Site 371S5030PKPQGPFSIRAGYSI
Site 372S5067FTIRAGESVRPKKIN
Site 373T5077PKKINNITVSFEGNP
Site 374S5079KINNITVSFEGNPSG
Site 375S5085VSFEGNPSGSKTPIT
Site 376S5087FEGNPSGSKTPITTK
Site 377T5089GNPSGSKTPITTKLT
Site 378T5092SGSKTPITTKLTVSC
Site 379T5096TPITTKLTVSCPPGE
Site 380S5098ITTKLTVSCPPGEGS
Site 381S5105SCPPGEGSETGVKWV
Site 382T5107PPGEGSETGVKWVYY
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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