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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACSF3
Full Name:
Acyl-CoA synthetase family member 3, mitochondrial
Alias:
Type:
Mass (Da):
64096
Number AA:
576
UniProt ID:
Q4G176
International Prot ID:
IPI00166395
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0016874
GO:0016877
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006629
GO:0006631
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S29
A
P
A
R
H
R
G
S
G
L
L
H
T
A
P
Site 2
T34
R
G
S
G
L
L
H
T
A
P
V
A
R
S
D
Site 3
S40
H
T
A
P
V
A
R
S
D
R
S
A
P
V
F
Site 4
S43
P
V
A
R
S
D
R
S
A
P
V
F
T
R
A
Site 5
T67
V
D
Q
H
G
R
H
T
Y
R
E
L
Y
S
R
Site 6
Y68
D
Q
H
G
R
H
T
Y
R
E
L
Y
S
R
S
Site 7
Y72
R
H
T
Y
R
E
L
Y
S
R
S
L
R
L
S
Site 8
S73
H
T
Y
R
E
L
Y
S
R
S
L
R
L
S
Q
Site 9
S75
Y
R
E
L
Y
S
R
S
L
R
L
S
Q
E
I
Site 10
S79
Y
S
R
S
L
R
L
S
Q
E
I
C
R
L
C
Site 11
S99
D
L
R
E
E
R
V
S
F
L
C
A
N
D
A
Site 12
Y126
G
G
V
A
V
P
L
Y
R
K
H
P
A
A
Q
Site 13
Y136
H
P
A
A
Q
L
E
Y
V
I
C
D
S
Q
S
Site 14
S157
Q
E
Y
L
E
L
L
S
P
V
V
R
K
L
G
Site 15
Y201
N
K
G
A
M
I
I
Y
T
S
G
T
T
G
R
Site 16
S214
G
R
P
K
G
V
L
S
T
H
Q
N
I
R
A
Site 17
T215
R
P
K
G
V
L
S
T
H
Q
N
I
R
A
V
Site 18
S281
Q
V
W
E
K
F
L
S
S
E
T
P
R
I
N
Site 19
T284
E
K
F
L
S
S
E
T
P
R
I
N
V
F
M
Site 20
Y297
F
M
A
V
P
T
I
Y
T
K
L
M
E
Y
Y
Site 21
Y303
I
Y
T
K
L
M
E
Y
Y
D
R
H
F
T
Q
Site 22
Y304
Y
T
K
L
M
E
Y
Y
D
R
H
F
T
Q
P
Site 23
Y355
G
H
T
L
L
E
R
Y
G
M
T
E
I
G
M
Site 24
S391
G
V
Q
V
R
I
V
S
E
N
P
Q
R
E
A
Site 25
Y401
P
Q
R
E
A
C
S
Y
T
I
H
A
E
G
D
Site 26
T412
A
E
G
D
E
R
G
T
K
V
T
P
G
F
E
Site 27
T415
D
E
R
G
T
K
V
T
P
G
F
E
E
K
E
Site 28
S431
E
L
L
V
R
G
P
S
V
F
R
E
Y
W
N
Site 29
Y436
G
P
S
V
F
R
E
Y
W
N
K
P
E
E
T
Site 30
S445
N
K
P
E
E
T
K
S
A
F
T
L
D
G
W
Site 31
Y466
V
V
F
K
D
G
Q
Y
W
I
R
G
R
T
S
Site 32
T472
Q
Y
W
I
R
G
R
T
S
V
D
I
I
K
T
Site 33
S485
K
T
G
G
Y
K
V
S
A
L
E
V
E
W
H
Site 34
S527
V
T
L
R
E
G
H
S
L
S
H
R
E
L
K
Site 35
S529
L
R
E
G
H
S
L
S
H
R
E
L
K
E
W
Site 36
Y544
A
R
N
V
L
A
P
Y
A
V
P
S
E
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation