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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTPN20A
Full Name:
Tyrosine-protein phosphatase non-receptor type 20
Alias:
BA142I17.1; EC 3.1.3.48; MGC142033; PTN20; Ptpn20a
Type:
Protein-tyrosine phosphatase
Mass (Da):
48423
Number AA:
420
UniProt ID:
Q4JDL3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004725
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
R
A
E
P
V
N
D
Y
E
G
N
D
S
E
A
Site 2
S20
N
D
Y
E
G
N
D
S
E
A
E
D
L
N
F
Site 3
T30
E
D
L
N
F
R
E
T
L
P
S
S
S
Q
E
Site 4
S33
N
F
R
E
T
L
P
S
S
S
Q
E
N
T
P
Site 5
S34
F
R
E
T
L
P
S
S
S
Q
E
N
T
P
R
Site 6
S35
R
E
T
L
P
S
S
S
Q
E
N
T
P
R
S
Site 7
T39
P
S
S
S
Q
E
N
T
P
R
S
K
V
F
E
Site 8
S42
S
Q
E
N
T
P
R
S
K
V
F
E
N
K
V
Site 9
S51
V
F
E
N
K
V
N
S
E
K
V
K
L
S
L
Site 10
S57
N
S
E
K
V
K
L
S
L
R
N
F
P
H
N
Site 11
Y66
R
N
F
P
H
N
D
Y
E
D
V
F
E
E
P
Site 12
S74
E
D
V
F
E
E
P
S
E
S
G
S
D
P
S
Site 13
S76
V
F
E
E
P
S
E
S
G
S
D
P
S
M
W
Site 14
S78
E
E
P
S
E
S
G
S
D
P
S
M
W
T
A
Site 15
S81
S
E
S
G
S
D
P
S
M
W
T
A
R
G
P
Site 16
S95
P
F
R
R
D
R
W
S
S
E
D
E
E
A
A
Site 17
S96
F
R
R
D
R
W
S
S
E
D
E
E
A
A
G
Site 18
S105
D
E
E
A
A
G
P
S
Q
A
L
S
P
L
L
Site 19
S109
A
G
P
S
Q
A
L
S
P
L
L
S
D
T
R
Site 20
S113
Q
A
L
S
P
L
L
S
D
T
R
K
I
V
S
Site 21
T115
L
S
P
L
L
S
D
T
R
K
I
V
S
E
G
Site 22
S120
S
D
T
R
K
I
V
S
E
G
E
L
D
Q
L
Site 23
S177
N
L
P
G
E
F
N
S
G
N
Q
P
S
N
R
Site 24
S182
F
N
S
G
N
Q
P
S
N
R
E
K
N
R
Y
Site 25
Y189
S
N
R
E
K
N
R
Y
R
D
I
L
P
Y
D
Site 26
Y195
R
Y
R
D
I
L
P
Y
D
S
T
R
V
P
L
Site 27
S197
R
D
I
L
P
Y
D
S
T
R
V
P
L
G
K
Site 28
T198
D
I
L
P
Y
D
S
T
R
V
P
L
G
K
S
Site 29
S205
T
R
V
P
L
G
K
S
K
D
Y
I
N
A
S
Site 30
Y208
P
L
G
K
S
K
D
Y
I
N
A
S
Y
I
R
Site 31
Y213
K
D
Y
I
N
A
S
Y
I
R
I
V
N
C
G
Site 32
Y225
N
C
G
E
E
Y
F
Y
I
A
T
Q
G
P
L
Site 33
T228
E
E
Y
F
Y
I
A
T
Q
G
P
L
L
S
T
Site 34
S234
A
T
Q
G
P
L
L
S
T
I
D
D
F
W
Q
Site 35
Y268
G
I
I
K
C
Y
H
Y
W
P
I
S
L
K
K
Site 36
Y294
E
N
Y
Q
I
L
Q
Y
F
I
I
R
M
F
Q
Site 37
S306
M
F
Q
V
V
E
K
S
T
G
T
S
H
S
V
Site 38
S310
V
E
K
S
T
G
T
S
H
S
V
K
Q
L
Q
Site 39
S312
K
S
T
G
T
S
H
S
V
K
Q
L
Q
F
T
Site 40
T319
S
V
K
Q
L
Q
F
T
K
W
P
D
H
G
T
Site 41
T326
T
K
W
P
D
H
G
T
P
A
S
A
D
S
F
Site 42
S329
P
D
H
G
T
P
A
S
A
D
S
F
I
K
Y
Site 43
S332
G
T
P
A
S
A
D
S
F
I
K
Y
I
R
Y
Site 44
Y336
S
A
D
S
F
I
K
Y
I
R
Y
A
R
K
S
Site 45
Y339
S
F
I
K
Y
I
R
Y
A
R
K
S
H
L
T
Site 46
S343
Y
I
R
Y
A
R
K
S
H
L
T
G
P
M
V
Site 47
T346
Y
A
R
K
S
H
L
T
G
P
M
V
V
H
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation