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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF658B
Full Name:
Zinc finger protein 658B
Alias:
Type:
Mass (Da):
94331
Number AA:
819
UniProt ID:
Q4V348
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
T
D
K
R
G
K
C
S
D
L
N
E
Y
G
T
Site 2
T33
S
D
L
N
E
Y
G
T
S
C
D
K
T
T
A
Site 3
S34
D
L
N
E
Y
G
T
S
C
D
K
T
T
A
V
Site 4
T38
Y
G
T
S
C
D
K
T
T
A
V
E
Y
N
K
Site 5
Y53
V
H
M
A
M
T
H
Y
E
C
N
E
R
G
I
Site 6
S63
N
E
R
G
I
N
F
S
R
K
S
P
L
T
Q
Site 7
S66
G
I
N
F
S
R
K
S
P
L
T
Q
S
Q
R
Site 8
T69
F
S
R
K
S
P
L
T
Q
S
Q
R
T
I
T
Site 9
S71
R
K
S
P
L
T
Q
S
Q
R
T
I
T
G
W
Site 10
T76
T
Q
S
Q
R
T
I
T
G
W
S
A
F
E
S
Site 11
S91
N
K
C
E
E
N
F
S
Q
S
S
A
H
I
V
Site 12
T102
A
H
I
V
H
Q
K
T
Q
A
G
D
K
F
G
Site 13
Y119
N
E
C
T
D
A
L
Y
Q
K
L
D
F
T
A
Site 14
T132
T
A
H
Q
R
I
H
T
D
F
T
A
H
Q
K
Site 15
Y141
F
T
A
H
Q
K
F
Y
L
S
D
E
H
G
K
Site 16
Y154
G
K
C
R
K
S
F
Y
W
K
A
H
L
I
Q
Site 17
S167
I
Q
H
E
R
P
H
S
G
E
K
T
Y
Q
Y
Site 18
T171
R
P
H
S
G
E
K
T
Y
Q
Y
E
E
C
A
Site 19
Y174
S
G
E
K
T
Y
Q
Y
E
E
C
A
K
S
F
Site 20
S180
Q
Y
E
E
C
A
K
S
F
C
S
S
S
H
P
Site 21
S184
C
A
K
S
F
C
S
S
S
H
P
I
Q
H
P
Site 22
S185
A
K
S
F
C
S
S
S
H
P
I
Q
H
P
G
Site 23
T193
H
P
I
Q
H
P
G
T
Y
V
G
F
K
L
Y
Site 24
Y194
P
I
Q
H
P
G
T
Y
V
G
F
K
L
Y
E
Site 25
Y200
T
Y
V
G
F
K
L
Y
E
C
N
E
C
G
K
Site 26
S213
G
K
A
F
C
Q
N
S
N
L
S
K
H
L
R
Site 27
T223
S
K
H
L
R
I
H
T
K
E
K
P
C
D
N
Site 28
S236
D
N
N
G
C
G
R
S
Y
K
S
P
L
I
G
Site 29
Y237
N
N
G
C
G
R
S
Y
K
S
P
L
I
G
H
Site 30
S239
G
C
G
R
S
Y
K
S
P
L
I
G
H
Q
K
Site 31
T247
P
L
I
G
H
Q
K
T
D
A
E
M
E
L
C
Site 32
Y259
E
L
C
G
G
S
E
Y
G
K
T
S
H
L
K
Site 33
T262
G
G
S
E
Y
G
K
T
S
H
L
K
G
H
Q
Site 34
S263
G
S
E
Y
G
K
T
S
H
L
K
G
H
Q
R
Site 35
Y278
I
L
M
G
E
K
P
Y
E
C
I
E
C
G
K
Site 36
T286
E
C
I
E
C
G
K
T
F
S
K
T
S
H
L
Site 37
S288
I
E
C
G
K
T
F
S
K
T
S
H
L
R
A
Site 38
T290
C
G
K
T
F
S
K
T
S
H
L
R
A
H
Q
Site 39
S291
G
K
T
F
S
K
T
S
H
L
R
A
H
Q
R
Site 40
T301
R
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 41
Y306
I
H
T
G
E
K
P
Y
E
C
V
E
C
E
K
Site 42
S316
V
E
C
E
K
T
F
S
H
K
T
H
L
S
V
Site 43
T319
E
K
T
F
S
H
K
T
H
L
S
V
H
Q
R
Site 44
T329
S
V
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 45
Y334
V
H
T
G
E
K
P
Y
E
C
N
D
C
G
K
Site 46
S347
G
K
S
F
T
Y
N
S
A
L
R
A
H
Q
R
Site 47
S365
G
E
K
P
Y
E
C
S
D
C
E
K
T
F
A
Site 48
T370
E
C
S
D
C
E
K
T
F
A
H
N
S
A
L
Site 49
S375
E
K
T
F
A
H
N
S
A
L
R
A
H
H
R
Site 50
T385
R
A
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 51
Y390
I
H
T
G
E
K
P
Y
E
C
N
E
C
G
R
Site 52
S403
G
R
S
F
A
H
I
S
V
L
K
A
H
Q
R
Site 53
T413
K
A
H
Q
R
I
H
T
R
E
K
P
Y
E
C
Site 54
Y418
I
H
T
R
E
K
P
Y
E
C
N
E
C
G
R
Site 55
T428
N
E
C
G
R
S
F
T
Y
N
S
A
L
R
A
Site 56
S431
G
R
S
F
T
Y
N
S
A
L
R
A
H
Q
R
Site 57
T441
R
A
H
Q
R
I
H
T
G
R
K
P
Y
E
C
Site 58
Y446
I
H
T
G
R
K
P
Y
E
C
S
D
C
E
K
Site 59
S449
G
R
K
P
Y
E
C
S
D
C
E
K
T
F
A
Site 60
S459
E
K
T
F
A
H
N
S
A
L
K
I
H
Q
R
Site 61
T469
K
I
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 62
S487
E
K
T
F
A
H
N
S
A
L
R
A
H
Q
N
Site 63
Y502
I
H
T
G
E
K
L
Y
E
C
S
E
C
G
K
Site 64
T510
E
C
S
E
C
G
K
T
F
F
Q
K
T
R
L
Site 65
T515
G
K
T
F
F
Q
K
T
R
L
S
T
H
R
R
Site 66
S518
F
F
Q
K
T
R
L
S
T
H
R
R
I
H
T
Site 67
T519
F
Q
K
T
R
L
S
T
H
R
R
I
H
T
G
Site 68
T525
S
T
H
R
R
I
H
T
G
E
K
P
Y
E
C
Site 69
Y530
I
H
T
G
E
K
P
Y
E
C
S
K
C
G
K
Site 70
S533
G
E
K
P
Y
E
C
S
K
C
G
K
T
F
S
Site 71
T538
E
C
S
K
C
G
K
T
F
S
Q
K
S
Y
L
Site 72
S540
S
K
C
G
K
T
F
S
Q
K
S
Y
L
S
G
Site 73
S543
G
K
T
F
S
Q
K
S
Y
L
S
G
H
E
R
Site 74
Y544
K
T
F
S
Q
K
S
Y
L
S
G
H
E
R
I
Site 75
S546
F
S
Q
K
S
Y
L
S
G
H
E
R
I
H
T
Site 76
T553
S
G
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 77
Y558
I
H
T
G
E
K
P
Y
E
C
N
V
C
G
K
Site 78
T581
I
V
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 79
Y586
I
H
T
G
E
K
P
Y
E
C
N
E
C
G
K
Site 80
T609
C
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 81
T622
E
C
N
E
C
G
K
T
F
A
D
N
S
A
L
Site 82
S627
G
K
T
F
A
D
N
S
A
L
R
A
H
H
R
Site 83
Y642
I
H
T
G
E
K
P
Y
E
C
N
D
C
G
K
Site 84
T650
E
C
N
D
C
G
K
T
F
S
K
T
S
H
L
Site 85
S652
N
D
C
G
K
T
F
S
K
T
S
H
L
R
A
Site 86
T654
C
G
K
T
F
S
K
T
S
H
L
R
A
H
L
Site 87
S655
G
K
T
F
S
K
T
S
H
L
R
A
H
L
R
Site 88
T663
H
L
R
A
H
L
R
T
R
S
G
E
K
P
Y
Site 89
S665
R
A
H
L
R
T
R
S
G
E
K
P
Y
E
C
Site 90
Y670
T
R
S
G
E
K
P
Y
E
C
S
E
C
G
K
Site 91
S673
G
E
K
P
Y
E
C
S
E
C
G
K
T
F
S
Site 92
T678
E
C
S
E
C
G
K
T
F
S
E
K
S
Y
V
Site 93
S680
S
E
C
G
K
T
F
S
E
K
S
Y
V
S
A
Site 94
S683
G
K
T
F
S
E
K
S
Y
V
S
A
H
Q
R
Site 95
Y684
K
T
F
S
E
K
S
Y
V
S
A
H
Q
R
V
Site 96
T693
S
A
H
Q
R
V
H
T
G
E
K
P
Y
E
C
Site 97
Y698
V
H
T
G
E
K
P
Y
E
C
N
V
C
G
K
Site 98
S711
G
K
P
F
A
H
N
S
T
L
R
V
H
Q
R
Site 99
T712
K
P
F
A
H
N
S
T
L
R
V
H
Q
R
I
Site 100
T721
R
V
H
Q
R
I
H
T
G
E
K
S
Y
E
C
Site 101
Y726
I
H
T
G
E
K
S
Y
E
C
N
D
C
G
K
Site 102
T734
E
C
N
D
C
G
K
T
F
S
Q
K
S
H
L
Site 103
S736
N
D
C
G
K
T
F
S
Q
K
S
H
L
S
A
Site 104
S739
G
K
T
F
S
Q
K
S
H
L
S
A
H
Q
R
Site 105
S742
F
S
Q
K
S
H
L
S
A
H
Q
R
I
H
T
Site 106
T749
S
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 107
S767
G
K
A
F
A
Q
N
S
T
L
R
V
H
Q
R
Site 108
T768
K
A
F
A
Q
N
S
T
L
R
V
H
Q
R
I
Site 109
T777
R
V
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 110
Y782
I
H
T
G
E
K
P
Y
E
C
D
E
C
G
K
Site 111
T790
E
C
D
E
C
G
K
T
F
V
R
K
A
A
L
Site 112
T806
V
H
H
T
R
M
H
T
R
E
K
T
L
A
C
Site 113
T810
R
M
H
T
R
E
K
T
L
A
C
N
G
F
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation