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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMOT
Full Name:
Angiomotin
Alias:
KIAA1071
Type:
Mass (Da):
118085
Number AA:
1084
UniProt ID:
Q4VCS5
International Prot ID:
IPI00163085
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005884
GO:0009986
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0043532
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0007043
GO:0043116
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
R
N
S
E
E
Q
P
S
G
G
T
T
V
L
Q
Site 2
T13
E
Q
P
S
G
G
T
T
V
L
Q
R
L
L
Q
Site 3
Y25
L
L
Q
E
Q
L
R
Y
G
N
P
S
E
N
R
Site 4
S29
Q
L
R
Y
G
N
P
S
E
N
R
S
L
L
A
Site 5
S33
G
N
P
S
E
N
R
S
L
L
A
I
H
Q
Q
Site 6
S50
G
N
G
P
P
F
P
S
G
S
G
N
P
G
P
Site 7
S52
G
P
P
F
P
S
G
S
G
N
P
G
P
Q
S
Site 8
S59
S
G
N
P
G
P
Q
S
D
V
L
S
P
Q
D
Site 9
S63
G
P
Q
S
D
V
L
S
P
Q
D
H
H
Q
Q
Site 10
S97
L
I
M
E
K
Q
L
S
P
R
M
Q
N
N
E
Site 11
T108
Q
N
N
E
E
L
P
T
Y
E
E
A
K
V
Q
Site 12
Y109
N
N
E
E
L
P
T
Y
E
E
A
K
V
Q
S
Site 13
Y118
E
A
K
V
Q
S
Q
Y
F
R
G
Q
Q
H
A
Site 14
S148
M
R
T
E
G
R
P
S
V
Q
R
L
N
P
G
Site 15
S173
L
K
Q
G
H
V
R
S
L
S
E
R
L
M
Q
Site 16
S175
Q
G
H
V
R
S
L
S
E
R
L
M
Q
M
S
Site 17
S182
S
E
R
L
M
Q
M
S
L
A
T
S
G
V
K
Site 18
S186
M
Q
M
S
L
A
T
S
G
V
K
A
H
P
P
Site 19
T195
V
K
A
H
P
P
V
T
S
A
P
L
S
P
P
Site 20
S196
K
A
H
P
P
V
T
S
A
P
L
S
P
P
Q
Site 21
S200
P
V
T
S
A
P
L
S
P
P
Q
P
N
D
L
Site 22
Y208
P
P
Q
P
N
D
L
Y
K
N
P
T
S
S
S
Site 23
T212
N
D
L
Y
K
N
P
T
S
S
S
E
F
Y
K
Site 24
S213
D
L
Y
K
N
P
T
S
S
S
E
F
Y
K
A
Site 25
S215
Y
K
N
P
T
S
S
S
E
F
Y
K
A
Q
G
Site 26
Y218
P
T
S
S
S
E
F
Y
K
A
Q
G
P
L
P
Site 27
S229
G
P
L
P
N
Q
H
S
L
K
G
M
E
H
R
Site 28
Y242
H
R
G
P
P
P
E
Y
P
F
K
G
M
P
P
Site 29
S251
F
K
G
M
P
P
Q
S
V
V
C
K
P
Q
E
Site 30
Y263
P
Q
E
P
G
H
F
Y
S
E
H
R
L
N
Q
Site 31
S264
Q
E
P
G
H
F
Y
S
E
H
R
L
N
Q
P
Site 32
Y281
T
E
G
Q
L
M
R
Y
Q
H
P
P
E
Y
G
Site 33
Y287
R
Y
Q
H
P
P
E
Y
G
A
A
R
P
A
Q
Site 34
S297
A
R
P
A
Q
D
I
S
L
P
L
S
A
R
N
Site 35
S301
Q
D
I
S
L
P
L
S
A
R
N
S
Q
P
H
Site 36
S305
L
P
L
S
A
R
N
S
Q
P
H
S
P
T
S
Site 37
S309
A
R
N
S
Q
P
H
S
P
T
S
S
L
T
S
Site 38
T311
N
S
Q
P
H
S
P
T
S
S
L
T
S
G
G
Site 39
S312
S
Q
P
H
S
P
T
S
S
L
T
S
G
G
S
Site 40
S313
Q
P
H
S
P
T
S
S
L
T
S
G
G
S
L
Site 41
T315
H
S
P
T
S
S
L
T
S
G
G
S
L
P
L
Site 42
S319
S
S
L
T
S
G
G
S
L
P
L
L
Q
S
P
Site 43
S325
G
S
L
P
L
L
Q
S
P
P
S
T
R
L
S
Site 44
S328
P
L
L
Q
S
P
P
S
T
R
L
S
P
A
R
Site 45
T329
L
L
Q
S
P
P
S
T
R
L
S
P
A
R
H
Site 46
S332
S
P
P
S
T
R
L
S
P
A
R
H
P
L
V
Site 47
Y367
Q
A
H
Q
G
D
H
Y
R
L
S
Q
P
G
L
Site 48
S370
Q
G
D
H
Y
R
L
S
Q
P
G
L
S
Q
Q
Site 49
S375
R
L
S
Q
P
G
L
S
Q
Q
Q
Q
Q
Q
Q
Site 50
S408
Q
Q
P
G
E
A
Y
S
A
M
P
R
A
Q
P
Site 51
S416
A
M
P
R
A
Q
P
S
S
A
S
Y
Q
P
V
Site 52
S417
M
P
R
A
Q
P
S
S
A
S
Y
Q
P
V
P
Site 53
S419
R
A
Q
P
S
S
A
S
Y
Q
P
V
P
A
D
Site 54
Y420
A
Q
P
S
S
A
S
Y
Q
P
V
P
A
D
P
Site 55
S442
Q
Q
M
V
E
I
L
S
D
E
N
R
N
L
R
Site 56
S473
E
T
E
I
Q
R
V
S
E
A
Y
E
N
L
V
Site 57
Y476
I
Q
R
V
S
E
A
Y
E
N
L
V
K
S
S
Site 58
S484
E
N
L
V
K
S
S
S
K
R
E
A
L
E
K
Site 59
T517
D
L
R
E
R
L
E
T
A
N
K
Q
L
A
E
Site 60
Y527
K
Q
L
A
E
K
E
Y
E
G
S
E
D
T
R
Site 61
S530
A
E
K
E
Y
E
G
S
E
D
T
R
K
T
I
Site 62
T536
G
S
E
D
T
R
K
T
I
S
Q
L
F
A
K
Site 63
S538
E
D
T
R
K
T
I
S
Q
L
F
A
K
N
K
Site 64
S547
L
F
A
K
N
K
E
S
Q
R
E
K
E
K
L
Site 65
T564
E
L
A
T
A
R
S
T
N
E
D
Q
R
R
H
Site 66
S580
E
I
R
D
Q
A
L
S
N
A
Q
A
K
V
V
Site 67
Y599
E
L
K
K
K
Q
V
Y
V
D
K
V
E
K
M
Site 68
T629
Q
L
E
H
R
L
R
T
R
L
E
R
E
L
E
Site 69
S637
R
L
E
R
E
L
E
S
L
R
I
Q
Q
R
Q
Site 70
T679
L
A
L
E
A
D
M
T
K
W
E
Q
K
Y
L
Site 71
Y685
M
T
K
W
E
Q
K
Y
L
E
E
N
V
M
R
Site 72
T708
T
V
A
A
Q
R
D
T
T
V
I
S
H
S
P
Site 73
T709
V
A
A
Q
R
D
T
T
V
I
S
H
S
P
N
Site 74
S712
Q
R
D
T
T
V
I
S
H
S
P
N
T
S
Y
Site 75
S714
D
T
T
V
I
S
H
S
P
N
T
S
Y
D
T
Site 76
S718
I
S
H
S
P
N
T
S
Y
D
T
A
L
E
A
Site 77
Y719
S
H
S
P
N
T
S
Y
D
T
A
L
E
A
R
Site 78
T750
D
M
E
G
R
I
K
T
L
H
A
Q
I
I
E
Site 79
S774
Q
R
S
R
K
E
P
S
K
T
E
Q
L
S
C
Site 80
T776
S
R
K
E
P
S
K
T
E
Q
L
S
C
M
R
Site 81
S780
P
S
K
T
E
Q
L
S
C
M
R
P
A
K
S
Site 82
S787
S
C
M
R
P
A
K
S
L
M
S
I
S
N
A
Site 83
S790
R
P
A
K
S
L
M
S
I
S
N
A
G
S
G
Site 84
S796
M
S
I
S
N
A
G
S
G
L
L
S
H
S
S
Site 85
S800
N
A
G
S
G
L
L
S
H
S
S
T
L
T
G
Site 86
S802
G
S
G
L
L
S
H
S
S
T
L
T
G
S
P
Site 87
T806
L
S
H
S
S
T
L
T
G
S
P
I
M
E
E
Site 88
S808
H
S
S
T
L
T
G
S
P
I
M
E
E
K
R
Site 89
S819
E
E
K
R
D
D
K
S
W
K
G
S
L
G
I
Site 90
S823
D
D
K
S
W
K
G
S
L
G
I
L
L
G
G
Site 91
Y832
G
I
L
L
G
G
D
Y
R
A
E
Y
V
P
S
Site 92
Y836
G
G
D
Y
R
A
E
Y
V
P
S
T
P
S
P
Site 93
S839
Y
R
A
E
Y
V
P
S
T
P
S
P
V
P
P
Site 94
T840
R
A
E
Y
V
P
S
T
P
S
P
V
P
P
S
Site 95
S842
E
Y
V
P
S
T
P
S
P
V
P
P
S
T
P
Site 96
S847
T
P
S
P
V
P
P
S
T
P
L
L
S
A
H
Site 97
T848
P
S
P
V
P
P
S
T
P
L
L
S
A
H
S
Site 98
S852
P
P
S
T
P
L
L
S
A
H
S
K
T
G
S
Site 99
S855
T
P
L
L
S
A
H
S
K
T
G
S
R
D
C
Site 100
T857
L
L
S
A
H
S
K
T
G
S
R
D
C
S
T
Site 101
S859
S
A
H
S
K
T
G
S
R
D
C
S
T
Q
T
Site 102
S863
K
T
G
S
R
D
C
S
T
Q
T
E
R
G
T
Site 103
T864
T
G
S
R
D
C
S
T
Q
T
E
R
G
T
E
Site 104
T866
S
R
D
C
S
T
Q
T
E
R
G
T
E
S
N
Site 105
T870
S
T
Q
T
E
R
G
T
E
S
N
K
T
A
A
Site 106
T875
R
G
T
E
S
N
K
T
A
A
V
A
P
I
S
Site 107
T1001
Q
A
S
A
P
A
Q
T
Q
A
P
T
S
A
P
Site 108
S1006
A
Q
T
Q
A
P
T
S
A
P
A
V
A
P
T
Site 109
T1013
S
A
P
A
V
A
P
T
P
A
P
T
P
T
P
Site 110
T1019
P
T
P
A
P
T
P
T
P
A
V
A
Q
A
E
Site 111
S1030
A
Q
A
E
V
P
A
S
P
A
T
G
P
G
P
Site 112
S1041
G
P
G
P
H
R
L
S
I
P
S
L
T
C
N
Site 113
S1044
P
H
R
L
S
I
P
S
L
T
C
N
P
D
K
Site 114
T1046
R
L
S
I
P
S
L
T
C
N
P
D
K
T
D
Site 115
T1052
L
T
C
N
P
D
K
T
D
G
P
V
F
H
S
Site 116
S1059
T
D
G
P
V
F
H
S
N
T
L
E
R
K
T
Site 117
T1061
G
P
V
F
H
S
N
T
L
E
R
K
T
P
I
Site 118
T1066
S
N
T
L
E
R
K
T
P
I
Q
I
L
G
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation