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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PABPC1L
Full Name:
Polyadenylate-binding protein 1-like
Alias:
Type:
Mass (Da):
68392
Number AA:
614
UniProt ID:
Q4VXU2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
G
Y
P
L
A
S
L
Y
V
G
D
L
H
P
D
Site 2
T23
G
D
L
H
P
D
V
T
E
A
M
L
Y
E
K
Site 3
Y28
D
V
T
E
A
M
L
Y
E
K
F
S
P
A
G
Site 4
S32
A
M
L
Y
E
K
F
S
P
A
G
P
I
L
S
Site 5
T48
R
V
C
R
D
V
A
T
R
R
S
L
G
Y
A
Site 6
S51
R
D
V
A
T
R
R
S
L
G
Y
A
Y
I
N
Site 7
Y54
A
T
R
R
S
L
G
Y
A
Y
I
N
F
Q
Q
Site 8
T71
D
A
E
R
A
L
D
T
M
N
F
E
M
L
K
Site 9
S87
Q
P
I
R
I
M
W
S
Q
R
D
P
G
L
R
Site 10
S96
R
D
P
G
L
R
K
S
G
V
G
N
I
F
I
Site 11
S109
F
I
K
N
L
E
D
S
I
D
N
K
A
L
Y
Site 12
Y116
S
I
D
N
K
A
L
Y
D
T
F
S
T
F
G
Site 13
T118
D
N
K
A
L
Y
D
T
F
S
T
F
G
N
I
Site 14
S175
V
F
V
G
H
F
K
S
R
R
E
R
E
A
E
Site 15
S212
Q
G
L
Q
D
L
F
S
Q
F
G
K
M
L
S
Site 16
S219
S
Q
F
G
K
M
L
S
V
K
V
M
R
D
N
Site 17
S227
V
K
V
M
R
D
N
S
G
H
S
R
C
F
G
Site 18
S257
H
M
N
G
K
E
V
S
G
R
L
L
Y
A
G
Site 19
Y262
E
V
S
G
R
L
L
Y
A
G
R
A
Q
K
R
Site 20
Y291
K
Q
D
R
L
R
R
Y
Q
G
V
N
L
Y
V
Site 21
Y297
R
Y
Q
G
V
N
L
Y
V
K
N
L
D
D
S
Site 22
S315
D
K
L
R
K
E
F
S
P
Y
G
V
I
T
S
Site 23
Y317
L
R
K
E
F
S
P
Y
G
V
I
T
S
A
K
Site 24
S341
G
F
G
F
V
C
F
S
S
P
E
E
A
T
K
Site 25
S342
F
G
F
V
C
F
S
S
P
E
E
A
T
K
A
Site 26
T379
E
E
R
K
A
I
L
T
N
Q
Y
M
Q
R
L
Site 27
Y382
K
A
I
L
T
N
Q
Y
M
Q
R
L
S
T
M
Site 28
S387
N
Q
Y
M
Q
R
L
S
T
M
R
T
L
S
N
Site 29
T388
Q
Y
M
Q
R
L
S
T
M
R
T
L
S
N
P
Site 30
T391
Q
R
L
S
T
M
R
T
L
S
N
P
L
L
G
Site 31
S399
L
S
N
P
L
L
G
S
F
Q
Q
P
S
S
Y
Site 32
S404
L
G
S
F
Q
Q
P
S
S
Y
F
L
P
A
M
Site 33
S405
G
S
F
Q
Q
P
S
S
Y
F
L
P
A
M
P
Site 34
Y406
S
F
Q
Q
P
S
S
Y
F
L
P
A
M
P
Q
Site 35
Y420
Q
P
P
A
Q
A
A
Y
Y
G
C
G
P
V
T
Site 36
Y421
P
P
A
Q
A
A
Y
Y
G
C
G
P
V
T
P
Site 37
T427
Y
Y
G
C
G
P
V
T
P
T
Q
P
A
P
R
Site 38
T436
T
Q
P
A
P
R
W
T
S
Q
P
P
R
P
S
Site 39
S437
Q
P
A
P
R
W
T
S
Q
P
P
R
P
S
C
Site 40
S443
T
S
Q
P
P
R
P
S
C
A
S
M
V
R
P
Site 41
S446
P
P
R
P
S
C
A
S
M
V
R
P
P
V
V
Site 42
S462
R
R
P
P
A
H
I
S
S
V
R
Q
A
S
T
Site 43
S463
R
P
P
A
H
I
S
S
V
R
Q
A
S
T
Q
Site 44
S468
I
S
S
V
R
Q
A
S
T
Q
V
P
R
T
V
Site 45
T469
S
S
V
R
Q
A
S
T
Q
V
P
R
T
V
P
Site 46
T474
A
S
T
Q
V
P
R
T
V
P
H
T
Q
R
V
Site 47
T478
V
P
R
T
V
P
H
T
Q
R
V
A
N
I
G
Site 48
S509
P
L
L
P
C
K
C
S
S
A
A
H
S
T
Y
Site 49
S510
L
L
P
C
K
C
S
S
A
A
H
S
T
Y
R
Site 50
S514
K
C
S
S
A
A
H
S
T
Y
R
V
Q
E
P
Site 51
Y516
S
S
A
A
H
S
T
Y
R
V
Q
E
P
A
V
Site 52
Y553
Q
M
I
G
E
R
L
Y
P
L
I
H
D
V
H
Site 53
S585
E
L
L
L
M
L
E
S
P
E
S
L
H
A
K
Site 54
S588
L
M
L
E
S
P
E
S
L
H
A
K
I
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation