KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FNDC1
Full Name:
Fibronectin type III domain-containing protein 1
Alias:
BA243O10.1; DJ322A24.1; Fibronectin type III domain containing 1; FNDC2; KIAA1866
Type:
Unknown function
Mass (Da):
199420
Number AA:
UniProt ID:
Q4ZHG4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
P
E
A
G
A
T
L
R
A
P
R
R
L
Site 2
S50
P
R
H
V
K
L
L
S
T
K
M
G
L
K
V
Site 3
T66
W
D
P
P
K
D
A
T
S
R
P
V
E
H
Y
Site 4
S67
D
P
P
K
D
A
T
S
R
P
V
E
H
Y
N
Site 5
Y73
T
S
R
P
V
E
H
Y
N
I
A
Y
G
K
S
Site 6
S80
Y
N
I
A
Y
G
K
S
L
K
S
L
K
Y
I
Site 7
S83
A
Y
G
K
S
L
K
S
L
K
Y
I
K
V
N
Site 8
Y86
K
S
L
K
S
L
K
Y
I
K
V
N
A
E
T
Site 9
S95
K
V
N
A
E
T
Y
S
F
L
I
E
D
V
E
Site 10
S117
L
L
T
A
E
N
H
S
G
V
S
R
P
V
Y
Site 11
Y124
S
G
V
S
R
P
V
Y
R
A
E
S
P
P
G
Site 12
S128
R
P
V
Y
R
A
E
S
P
P
G
G
E
W
I
Site 13
T151
G
P
G
P
F
N
E
T
V
T
E
K
E
V
P
Site 14
S168
P
L
R
V
R
V
R
S
S
D
D
R
L
S
V
Site 15
S169
L
R
V
R
V
R
S
S
D
D
R
L
S
V
A
Site 16
S174
R
S
S
D
D
R
L
S
V
A
W
K
A
P
R
Site 17
S183
A
W
K
A
P
R
L
S
G
A
K
S
P
R
R
Site 18
S187
P
R
L
S
G
A
K
S
P
R
R
S
R
G
F
Site 19
S191
G
A
K
S
P
R
R
S
R
G
F
L
L
G
Y
Site 20
Y198
S
R
G
F
L
L
G
Y
G
E
S
G
R
K
M
Site 21
S201
F
L
L
G
Y
G
E
S
G
R
K
M
N
Y
V
Site 22
Y207
E
S
G
R
K
M
N
Y
V
P
L
T
R
D
E
Site 23
T211
K
M
N
Y
V
P
L
T
R
D
E
R
T
H
E
Site 24
S231
S
E
S
V
Y
V
V
S
L
Q
S
M
N
S
Q
Site 25
S234
V
Y
V
V
S
L
Q
S
M
N
S
Q
G
R
S
Site 26
S237
V
S
L
Q
S
M
N
S
Q
G
R
S
Q
P
V
Site 27
S241
S
M
N
S
Q
G
R
S
Q
P
V
Y
R
A
A
Site 28
Y245
Q
G
R
S
Q
P
V
Y
R
A
A
L
T
K
R
Site 29
T250
P
V
Y
R
A
A
L
T
K
R
K
I
S
E
E
Site 30
S255
A
L
T
K
R
K
I
S
E
E
D
E
L
D
V
Site 31
S267
L
D
V
P
D
D
I
S
V
R
V
M
S
S
Q
Site 32
S294
K
Q
K
K
V
V
A
S
R
Q
Y
T
V
R
Y
Site 33
Y297
K
V
V
A
S
R
Q
Y
T
V
R
Y
R
E
K
Site 34
T298
V
V
A
S
R
Q
Y
T
V
R
Y
R
E
K
G
Site 35
Y301
S
R
Q
Y
T
V
R
Y
R
E
K
G
E
L
A
Site 36
Y312
G
E
L
A
R
W
D
Y
K
Q
I
A
N
R
R
Site 37
S338
Y
E
F
A
V
R
I
S
Q
G
E
R
D
G
K
Site 38
S347
G
E
R
D
G
K
W
S
T
S
V
F
Q
R
T
Site 39
S349
R
D
G
K
W
S
T
S
V
F
Q
R
T
P
E
Site 40
T354
S
T
S
V
F
Q
R
T
P
E
S
A
P
T
T
Site 41
S357
V
F
Q
R
T
P
E
S
A
P
T
T
A
P
E
Site 42
T360
R
T
P
E
S
A
P
T
T
A
P
E
N
L
N
Site 43
T361
T
P
E
S
A
P
T
T
A
P
E
N
L
N
V
Site 44
T376
W
P
V
N
G
K
P
T
V
V
A
A
S
W
D
Site 45
T388
S
W
D
A
L
P
E
T
E
G
K
V
K
E
Y
Site 46
S398
K
V
K
E
Y
I
L
S
Y
A
P
A
L
K
P
Site 47
S410
L
K
P
F
G
A
K
S
L
T
Y
P
G
D
T
Site 48
T412
P
F
G
A
K
S
L
T
Y
P
G
D
T
T
S
Site 49
Y413
F
G
A
K
S
L
T
Y
P
G
D
T
T
S
A
Site 50
S419
T
Y
P
G
D
T
T
S
A
L
V
D
G
L
Q
Site 51
T438
Y
L
F
K
I
R
A
T
N
R
R
G
L
G
P
Site 52
S479
P
E
K
P
E
P
S
S
P
S
P
R
A
P
A
Site 53
S481
K
P
E
P
S
S
P
S
P
R
A
P
A
S
S
Site 54
S487
P
S
P
R
A
P
A
S
S
Q
H
P
S
V
P
Site 55
S488
S
P
R
A
P
A
S
S
Q
H
P
S
V
P
A
Site 56
S492
P
A
S
S
Q
H
P
S
V
P
A
S
P
Q
G
Site 57
S496
Q
H
P
S
V
P
A
S
P
Q
G
R
N
A
K
Site 58
S537
A
E
E
L
D
L
Q
S
T
E
I
T
G
E
E
Site 59
T541
D
L
Q
S
T
E
I
T
G
E
E
E
L
G
S
Site 60
S548
T
G
E
E
E
L
G
S
R
E
D
S
P
M
S
Site 61
S552
E
L
G
S
R
E
D
S
P
M
S
P
S
D
T
Site 62
S555
S
R
E
D
S
P
M
S
P
S
D
T
Q
D
Q
Site 63
S557
E
D
S
P
M
S
P
S
D
T
Q
D
Q
K
R
Site 64
T559
S
P
M
S
P
S
D
T
Q
D
Q
K
R
T
L
Site 65
T565
D
T
Q
D
Q
K
R
T
L
R
P
P
S
R
H
Site 66
S570
K
R
T
L
R
P
P
S
R
H
G
H
S
V
V
Site 67
S575
P
P
S
R
H
G
H
S
V
V
A
P
G
R
T
Site 68
S603
G
V
D
K
P
G
F
S
L
A
T
Q
P
R
P
Site 69
S615
P
R
P
G
A
P
P
S
A
S
A
S
P
A
H
Site 70
S617
P
G
A
P
P
S
A
S
A
S
P
A
H
H
A
Site 71
S619
A
P
P
S
A
S
A
S
P
A
H
H
A
S
T
Site 72
S625
A
S
P
A
H
H
A
S
T
Q
G
T
S
H
R
Site 73
T626
S
P
A
H
H
A
S
T
Q
G
T
S
H
R
P
Site 74
T629
H
H
A
S
T
Q
G
T
S
H
R
P
S
L
P
Site 75
S630
H
A
S
T
Q
G
T
S
H
R
P
S
L
P
A
Site 76
S634
Q
G
T
S
H
R
P
S
L
P
A
S
L
N
D
Site 77
S638
H
R
P
S
L
P
A
S
L
N
D
N
D
L
V
Site 78
S647
N
D
N
D
L
V
D
S
D
E
D
E
R
A
V
Site 79
S656
E
D
E
R
A
V
G
S
L
H
P
K
G
A
F
Site 80
S671
A
Q
P
R
P
A
L
S
P
S
R
Q
S
P
S
Site 81
S673
P
R
P
A
L
S
P
S
R
Q
S
P
S
S
V
Site 82
S676
A
L
S
P
S
R
Q
S
P
S
S
V
L
R
D
Site 83
S679
P
S
R
Q
S
P
S
S
V
L
R
D
R
S
S
Site 84
S685
S
S
V
L
R
D
R
S
S
V
H
P
G
A
K
Site 85
S686
S
V
L
R
D
R
S
S
V
H
P
G
A
K
P
Site 86
S695
H
P
G
A
K
P
A
S
P
A
R
R
T
P
H
Site 87
T700
P
A
S
P
A
R
R
T
P
H
S
G
A
A
E
Site 88
S703
P
A
R
R
T
P
H
S
G
A
A
E
E
D
S
Site 89
S710
S
G
A
A
E
E
D
S
S
A
S
A
P
P
S
Site 90
S711
G
A
A
E
E
D
S
S
A
S
A
P
P
S
R
Site 91
S713
A
E
E
D
S
S
A
S
A
P
P
S
R
L
S
Site 92
S717
S
S
A
S
A
P
P
S
R
L
S
P
P
H
G
Site 93
S720
S
A
P
P
S
R
L
S
P
P
H
G
G
S
S
Site 94
S726
L
S
P
P
H
G
G
S
S
R
L
L
P
T
Q
Site 95
S727
S
P
P
H
G
G
S
S
R
L
L
P
T
Q
P
Site 96
T732
G
S
S
R
L
L
P
T
Q
P
H
L
S
S
P
Site 97
S737
L
P
T
Q
P
H
L
S
S
P
L
S
K
G
G
Site 98
S738
P
T
Q
P
H
L
S
S
P
L
S
K
G
G
K
Site 99
S741
P
H
L
S
S
P
L
S
K
G
G
K
D
G
E
Site 100
T753
D
G
E
D
A
P
A
T
N
S
N
A
P
S
R
Site 101
S755
E
D
A
P
A
T
N
S
N
A
P
S
R
S
T
Site 102
S759
A
T
N
S
N
A
P
S
R
S
T
M
S
S
S
Site 103
S761
N
S
N
A
P
S
R
S
T
M
S
S
S
V
S
Site 104
T762
S
N
A
P
S
R
S
T
M
S
S
S
V
S
S
Site 105
S764
A
P
S
R
S
T
M
S
S
S
V
S
S
H
L
Site 106
S765
P
S
R
S
T
M
S
S
S
V
S
S
H
L
S
Site 107
S766
S
R
S
T
M
S
S
S
V
S
S
H
L
S
S
Site 108
S768
S
T
M
S
S
S
V
S
S
H
L
S
S
R
T
Site 109
S769
T
M
S
S
S
V
S
S
H
L
S
S
R
T
Q
Site 110
S772
S
S
V
S
S
H
L
S
S
R
T
Q
V
S
E
Site 111
S773
S
V
S
S
H
L
S
S
R
T
Q
V
S
E
G
Site 112
T775
S
S
H
L
S
S
R
T
Q
V
S
E
G
A
E
Site 113
S784
V
S
E
G
A
E
A
S
D
G
E
S
H
G
D
Site 114
S788
A
E
A
S
D
G
E
S
H
G
D
G
D
R
E
Site 115
T804
G
G
R
Q
A
E
A
T
A
Q
T
L
R
A
R
Site 116
T807
Q
A
E
A
T
A
Q
T
L
R
A
R
P
A
S
Site 117
S814
T
L
R
A
R
P
A
S
G
H
F
H
L
L
R
Site 118
S831
P
F
A
A
N
G
R
S
P
S
R
F
S
I
G
Site 119
S833
A
A
N
G
R
S
P
S
R
F
S
I
G
R
G
Site 120
S836
G
R
S
P
S
R
F
S
I
G
R
G
P
R
L
Site 121
S846
R
G
P
R
L
Q
P
S
S
S
P
Q
S
T
V
Site 122
S847
G
P
R
L
Q
P
S
S
S
P
Q
S
T
V
P
Site 123
S848
P
R
L
Q
P
S
S
S
P
Q
S
T
V
P
S
Site 124
S851
Q
P
S
S
S
P
Q
S
T
V
P
S
R
A
H
Site 125
T852
P
S
S
S
P
Q
S
T
V
P
S
R
A
H
P
Site 126
S855
S
P
Q
S
T
V
P
S
R
A
H
P
R
V
P
Site 127
S863
R
A
H
P
R
V
P
S
H
S
D
S
H
P
K
Site 128
S865
H
P
R
V
P
S
H
S
D
S
H
P
K
L
S
Site 129
S867
R
V
P
S
H
S
D
S
H
P
K
L
S
S
G
Site 130
T888
D
E
K
P
L
P
A
T
V
V
N
D
H
V
P
Site 131
S896
V
V
N
D
H
V
P
S
S
S
R
Q
P
I
S
Site 132
S897
V
N
D
H
V
P
S
S
S
R
Q
P
I
S
R
Site 133
S898
N
D
H
V
P
S
S
S
R
Q
P
I
S
R
G
Site 134
S903
S
S
S
R
Q
P
I
S
R
G
W
E
D
L
R
Site 135
S912
G
W
E
D
L
R
R
S
P
Q
R
G
A
S
L
Site 136
S918
R
S
P
Q
R
G
A
S
L
H
R
K
E
P
I
Site 137
S931
P
I
P
E
N
P
K
S
T
G
A
D
T
H
P
Site 138
T936
P
K
S
T
G
A
D
T
H
P
Q
G
K
Y
S
Site 139
S943
T
H
P
Q
G
K
Y
S
S
L
A
S
K
A
Q
Site 140
S944
H
P
Q
G
K
Y
S
S
L
A
S
K
A
Q
D
Site 141
S947
G
K
Y
S
S
L
A
S
K
A
Q
D
V
Q
Q
Site 142
T960
Q
Q
S
T
D
A
D
T
E
G
H
S
P
K
A
Site 143
S964
D
A
D
T
E
G
H
S
P
K
A
Q
P
G
S
Site 144
S971
S
P
K
A
Q
P
G
S
T
D
R
H
A
S
P
Site 145
T972
P
K
A
Q
P
G
S
T
D
R
H
A
S
P
A
Site 146
S977
G
S
T
D
R
H
A
S
P
A
R
P
P
A
A
Site 147
S986
A
R
P
P
A
A
R
S
Q
Q
H
P
S
V
P
Site 148
S991
A
R
S
Q
Q
H
P
S
V
P
R
R
M
T
P
Site 149
T997
P
S
V
P
R
R
M
T
P
G
R
A
P
Q
Q
Site 150
S1013
P
P
P
P
V
A
T
S
Q
H
H
P
G
P
Q
Site 151
S1021
Q
H
H
P
G
P
Q
S
R
D
A
G
R
S
P
Site 152
S1027
Q
S
R
D
A
G
R
S
P
S
Q
P
R
L
S
Site 153
S1029
R
D
A
G
R
S
P
S
Q
P
R
L
S
L
T
Site 154
S1034
S
P
S
Q
P
R
L
S
L
T
Q
A
G
R
P
Site 155
T1036
S
Q
P
R
L
S
L
T
Q
A
G
R
P
R
P
Site 156
T1044
Q
A
G
R
P
R
P
T
S
Q
G
R
S
H
S
Site 157
S1045
A
G
R
P
R
P
T
S
Q
G
R
S
H
S
S
Site 158
S1049
R
P
T
S
Q
G
R
S
H
S
S
S
D
P
Y
Site 159
S1051
T
S
Q
G
R
S
H
S
S
S
D
P
Y
T
A
Site 160
S1053
Q
G
R
S
H
S
S
S
D
P
Y
T
A
S
S
Site 161
Y1056
S
H
S
S
S
D
P
Y
T
A
S
S
R
G
M
Site 162
T1057
H
S
S
S
D
P
Y
T
A
S
S
R
G
M
L
Site 163
S1059
S
S
D
P
Y
T
A
S
S
R
G
M
L
P
T
Site 164
T1066
S
S
R
G
M
L
P
T
A
L
Q
N
Q
D
E
Site 165
Y1079
D
E
D
A
Q
G
S
Y
D
D
D
S
T
E
V
Site 166
S1083
Q
G
S
Y
D
D
D
S
T
E
V
E
A
Q
D
Site 167
T1084
G
S
Y
D
D
D
S
T
E
V
E
A
Q
D
V
Site 168
S1106
R
A
K
E
A
A
A
S
L
P
K
H
Q
Q
V
Site 169
S1115
P
K
H
Q
Q
V
E
S
P
T
G
A
G
A
G
Site 170
S1127
G
A
G
G
D
H
R
S
Q
R
G
H
A
A
S
Site 171
S1134
S
Q
R
G
H
A
A
S
P
A
R
P
S
R
P
Site 172
S1139
A
A
S
P
A
R
P
S
R
P
G
G
P
Q
S
Site 173
S1146
S
R
P
G
G
P
Q
S
R
A
R
V
P
S
R
Site 174
S1152
Q
S
R
A
R
V
P
S
R
A
A
P
G
K
S
Site 175
S1159
S
R
A
A
P
G
K
S
E
P
P
S
K
R
P
Site 176
S1163
P
G
K
S
E
P
P
S
K
R
P
L
S
S
K
Site 177
S1168
P
P
S
K
R
P
L
S
S
K
S
Q
Q
S
V
Site 178
S1169
P
S
K
R
P
L
S
S
K
S
Q
Q
S
V
S
Site 179
S1171
K
R
P
L
S
S
K
S
Q
Q
S
V
S
A
E
Site 180
S1174
L
S
S
K
S
Q
Q
S
V
S
A
E
D
D
E
Site 181
S1176
S
K
S
Q
Q
S
V
S
A
E
D
D
E
E
E
Site 182
S1197
G
G
K
E
D
L
L
S
S
S
V
P
K
W
P
Site 183
S1198
G
K
E
D
L
L
S
S
S
V
P
K
W
P
S
Site 184
S1199
K
E
D
L
L
S
S
S
V
P
K
W
P
S
S
Site 185
S1205
S
S
V
P
K
W
P
S
S
S
T
P
R
G
G
Site 186
S1206
S
V
P
K
W
P
S
S
S
T
P
R
G
G
K
Site 187
S1207
V
P
K
W
P
S
S
S
T
P
R
G
G
K
D
Site 188
T1208
P
K
W
P
S
S
S
T
P
R
G
G
K
D
A
Site 189
S1218
G
G
K
D
A
D
G
S
L
A
K
E
E
R
E
Site 190
S1236
A
L
A
P
R
G
G
S
L
A
P
V
K
R
P
Site 191
S1250
P
L
P
P
P
P
G
S
S
P
R
A
S
H
V
Site 192
S1251
L
P
P
P
P
G
S
S
P
R
A
S
H
V
P
Site 193
S1255
P
G
S
S
P
R
A
S
H
V
P
S
R
P
P
Site 194
S1259
P
R
A
S
H
V
P
S
R
P
P
P
R
S
A
Site 195
S1265
P
S
R
P
P
P
R
S
A
A
T
V
S
P
V
Site 196
T1268
P
P
P
R
S
A
A
T
V
S
P
V
A
G
T
Site 197
S1270
P
R
S
A
A
T
V
S
P
V
A
G
T
H
P
Site 198
Y1281
G
T
H
P
W
P
Q
Y
T
T
R
A
P
P
G
Site 199
T1282
T
H
P
W
P
Q
Y
T
T
R
A
P
P
G
H
Site 200
T1283
H
P
W
P
Q
Y
T
T
R
A
P
P
G
H
F
Site 201
S1291
R
A
P
P
G
H
F
S
T
T
P
M
L
S
L
Site 202
T1292
A
P
P
G
H
F
S
T
T
P
M
L
S
L
R
Site 203
T1293
P
P
G
H
F
S
T
T
P
M
L
S
L
R
Q
Site 204
S1297
F
S
T
T
P
M
L
S
L
R
Q
R
M
M
H
Site 205
S1312
A
R
F
R
N
P
L
S
R
Q
P
A
R
P
S
Site 206
S1319
S
R
Q
P
A
R
P
S
Y
R
Q
G
Y
N
G
Site 207
Y1320
R
Q
P
A
R
P
S
Y
R
Q
G
Y
N
G
R
Site 208
Y1324
R
P
S
Y
R
Q
G
Y
N
G
R
P
N
V
E
Site 209
S1338
E
G
K
V
L
P
G
S
N
G
K
P
N
G
Q
Site 210
Y1372
V
L
N
A
E
G
R
Y
L
Q
D
S
H
G
N
Site 211
S1376
E
G
R
Y
L
Q
D
S
H
G
N
P
L
R
I
Site 212
T1391
K
L
G
G
D
G
R
T
I
V
D
L
E
G
T
Site 213
T1398
T
I
V
D
L
E
G
T
P
V
V
S
P
D
G
Site 214
T1416
F
G
Q
G
R
H
G
T
P
L
A
N
A
Q
D
Site 215
T1444
L
E
V
I
K
K
T
T
H
P
P
T
T
T
M
Site 216
T1448
K
K
T
T
H
P
P
T
T
T
M
Q
P
T
T
Site 217
T1450
T
T
H
P
P
T
T
T
M
Q
P
T
T
T
T
Site 218
T1456
T
T
M
Q
P
T
T
T
T
T
P
L
P
T
T
Site 219
T1458
M
Q
P
T
T
T
T
T
P
L
P
T
T
T
T
Site 220
T1463
T
T
T
P
L
P
T
T
T
T
P
R
P
T
T
Site 221
T1465
T
P
L
P
T
T
T
T
P
R
P
T
T
A
T
Site 222
T1469
T
T
T
T
P
R
P
T
T
A
T
T
R
R
T
Site 223
T1470
T
T
T
P
R
P
T
T
A
T
T
R
R
T
T
Site 224
T1472
T
P
R
P
T
T
A
T
T
R
R
T
T
T
R
Site 225
T1473
P
R
P
T
T
A
T
T
R
R
T
T
T
R
R
Site 226
T1476
T
T
A
T
T
R
R
T
T
T
R
R
P
T
T
Site 227
T1477
T
A
T
T
R
R
T
T
T
R
R
P
T
T
T
Site 228
T1478
A
T
T
R
R
T
T
T
R
R
P
T
T
T
V
Site 229
T1482
R
T
T
T
R
R
P
T
T
T
V
R
T
T
T
Site 230
T1483
T
T
T
R
R
P
T
T
T
V
R
T
T
T
R
Site 231
T1484
T
T
R
R
P
T
T
T
V
R
T
T
T
R
T
Site 232
T1488
P
T
T
T
V
R
T
T
T
R
T
T
T
T
T
Site 233
T1489
T
T
T
V
R
T
T
T
R
T
T
T
T
T
T
Site 234
T1491
T
V
R
T
T
T
R
T
T
T
T
T
T
P
K
Site 235
T1492
V
R
T
T
T
R
T
T
T
T
T
T
P
K
P
Site 236
T1493
R
T
T
T
R
T
T
T
T
T
T
P
K
P
T
Site 237
T1494
T
T
T
R
T
T
T
T
T
T
P
K
P
T
T
Site 238
T1495
T
T
R
T
T
T
T
T
T
P
K
P
T
T
P
Site 239
T1496
T
R
T
T
T
T
T
T
P
K
P
T
T
P
I
Site 240
T1501
T
T
T
P
K
P
T
T
P
I
P
T
C
P
P
Site 241
T1505
K
P
T
T
P
I
P
T
C
P
P
G
T
L
E
Site 242
T1510
I
P
T
C
P
P
G
T
L
E
R
H
D
D
D
Site 243
S1523
D
D
G
N
L
I
M
S
S
N
G
I
P
E
C
Site 244
S1538
Y
A
E
E
D
E
F
S
G
L
E
T
D
T
A
Site 245
T1542
D
E
F
S
G
L
E
T
D
T
A
V
P
T
E
Site 246
T1544
F
S
G
L
E
T
D
T
A
V
P
T
E
E
A
Site 247
Y1552
A
V
P
T
E
E
A
Y
V
I
Y
D
E
D
Y
Site 248
Y1555
T
E
E
A
Y
V
I
Y
D
E
D
Y
E
F
E
Site 249
Y1559
Y
V
I
Y
D
E
D
Y
E
F
E
T
S
R
P
Site 250
T1563
D
E
D
Y
E
F
E
T
S
R
P
P
T
T
T
Site 251
S1564
E
D
Y
E
F
E
T
S
R
P
P
T
T
T
E
Site 252
T1568
F
E
T
S
R
P
P
T
T
T
E
P
S
T
T
Site 253
T1569
E
T
S
R
P
P
T
T
T
E
P
S
T
T
A
Site 254
T1570
T
S
R
P
P
T
T
T
E
P
S
T
T
A
T
Site 255
T1574
P
T
T
T
E
P
S
T
T
A
T
T
P
R
V
Site 256
T1577
T
E
P
S
T
T
A
T
T
P
R
V
I
P
E
Site 257
T1578
E
P
S
T
T
A
T
T
P
R
V
I
P
E
E
Site 258
S1589
I
P
E
E
G
A
I
S
S
F
P
E
E
E
F
Site 259
S1590
P
E
E
G
A
I
S
S
F
P
E
E
E
F
D
Site 260
Y1608
R
K
R
F
V
A
P
Y
V
T
Y
L
N
K
D
Site 261
Y1611
F
V
A
P
Y
V
T
Y
L
N
K
D
P
S
A
Site 262
S1617
T
Y
L
N
K
D
P
S
A
P
C
S
L
T
D
Site 263
S1621
K
D
P
S
A
P
C
S
L
T
D
A
L
D
H
Site 264
T1623
P
S
A
P
C
S
L
T
D
A
L
D
H
F
Q
Site 265
S1633
L
D
H
F
Q
V
D
S
L
D
E
I
I
P
N
Site 266
S1645
I
P
N
D
L
K
K
S
D
L
P
P
Q
H
A
Site 267
T1676
I
V
D
W
D
K
A
T
P
G
D
V
V
T
G
Site 268
S1690
G
Y
L
V
Y
S
A
S
Y
E
D
F
I
R
N
Site 269
S1700
D
F
I
R
N
K
W
S
T
Q
A
S
S
V
T
Site 270
T1701
F
I
R
N
K
W
S
T
Q
A
S
S
V
T
H
Site 271
S1704
N
K
W
S
T
Q
A
S
S
V
T
H
L
P
I
Site 272
Y1721
L
K
P
N
T
R
Y
Y
F
K
V
Q
A
Q
N
Site 273
Y1732
Q
A
Q
N
P
H
G
Y
G
P
I
S
P
S
V
Site 274
S1736
P
H
G
Y
G
P
I
S
P
S
V
S
F
V
T
Site 275
S1738
G
Y
G
P
I
S
P
S
V
S
F
V
T
E
S
Site 276
S1740
G
P
I
S
P
S
V
S
F
V
T
E
S
D
N
Site 277
T1743
S
P
S
V
S
F
V
T
E
S
D
N
P
L
L
Site 278
Y1772
A
F
K
H
D
P
S
Y
T
D
C
H
G
R
Q
Site 279
Y1786
Q
Y
V
K
R
T
W
Y
R
K
F
V
G
V
V
Site 280
Y1803
N
S
L
R
Y
K
I
Y
L
S
D
N
L
K
D
Site 281
S1805
L
R
Y
K
I
Y
L
S
D
N
L
K
D
T
F
Site 282
T1811
L
S
D
N
L
K
D
T
F
Y
S
I
G
D
S
Site 283
Y1813
D
N
L
K
D
T
F
Y
S
I
G
D
S
W
G
Site 284
S1814
N
L
K
D
T
F
Y
S
I
G
D
S
W
G
R
Site 285
S1818
T
F
Y
S
I
G
D
S
W
G
R
G
E
D
H
Site 286
T1837
D
S
H
L
D
G
R
T
G
P
Q
S
Y
V
E
Site 287
S1841
D
G
R
T
G
P
Q
S
Y
V
E
A
L
P
T
Site 288
Y1842
G
R
T
G
P
Q
S
Y
V
E
A
L
P
T
I
Site 289
T1848
S
Y
V
E
A
L
P
T
I
Q
G
Y
Y
R
Q
Site 290
Y1852
A
L
P
T
I
Q
G
Y
Y
R
Q
Y
R
Q
E
Site 291
Y1856
I
Q
G
Y
Y
R
Q
Y
R
Q
E
P
V
R
F
Site 292
Y1872
N
I
G
F
G
T
P
Y
Y
Y
V
G
W
Y
E
Site 293
Y1878
P
Y
Y
Y
V
G
W
Y
E
C
G
V
S
I
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation