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Updated November 2019
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Protein Info
Short Name:
MIDN
Full Name:
Midnolin
Alias:
Midbrain nucleolar protein
Type:
Mass (Da):
49213
Number AA:
468
UniProt ID:
Q504T8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
P
Q
P
G
G
A
R
S
C
R
R
G
A
P
G
Site 2
S37
P
M
S
L
A
I
H
S
T
T
G
T
R
Y
D
Site 3
T41
A
I
H
S
T
T
G
T
R
Y
D
L
A
V
P
Site 4
Y43
H
S
T
T
G
T
R
Y
D
L
A
V
P
P
D
Site 5
T52
L
A
V
P
P
D
E
T
V
E
G
L
R
K
R
Site 6
S61
E
G
L
R
K
R
L
S
Q
R
L
K
V
P
K
Site 7
T78
L
A
L
L
H
K
D
T
R
L
S
S
G
K
L
Site 8
S81
L
H
K
D
T
R
L
S
S
G
K
L
Q
E
F
Site 9
S82
H
K
D
T
R
L
S
S
G
K
L
Q
E
F
G
Site 10
S108
T
V
E
A
G
L
M
S
Q
A
S
R
P
E
Q
Site 11
S111
A
G
L
M
S
Q
A
S
R
P
E
Q
S
V
M
Site 12
S123
S
V
M
Q
A
L
E
S
L
T
E
T
Q
V
S
Site 13
T127
A
L
E
S
L
T
E
T
Q
V
S
D
F
L
S
Site 14
S130
S
L
T
E
T
Q
V
S
D
F
L
S
G
R
S
Site 15
S134
T
Q
V
S
D
F
L
S
G
R
S
P
L
T
L
Site 16
S137
S
D
F
L
S
G
R
S
P
L
T
L
A
L
R
Site 17
S183
A
A
A
R
G
D
P
S
I
A
S
P
V
S
S
Site 18
S186
R
G
D
P
S
I
A
S
P
V
S
S
P
C
R
Site 19
S189
P
S
I
A
S
P
V
S
S
P
C
R
P
V
S
Site 20
S190
S
I
A
S
P
V
S
S
P
C
R
P
V
S
S
Site 21
S196
S
S
P
C
R
P
V
S
S
A
A
R
V
P
P
Site 22
S197
S
P
C
R
P
V
S
S
A
A
R
V
P
P
V
Site 23
S207
R
V
P
P
V
P
T
S
P
S
P
A
S
P
S
Site 24
S209
P
P
V
P
T
S
P
S
P
A
S
P
S
P
I
Site 25
S212
P
T
S
P
S
P
A
S
P
S
P
I
T
A
G
Site 26
S214
S
P
S
P
A
S
P
S
P
I
T
A
G
S
F
Site 27
T217
P
A
S
P
S
P
I
T
A
G
S
F
R
S
H
Site 28
S220
P
S
P
I
T
A
G
S
F
R
S
H
A
A
S
Site 29
S223
I
T
A
G
S
F
R
S
H
A
A
S
T
T
C
Site 30
S227
S
F
R
S
H
A
A
S
T
T
C
P
E
Q
M
Site 31
S237
C
P
E
Q
M
D
C
S
P
T
A
S
S
S
A
Site 32
T239
E
Q
M
D
C
S
P
T
A
S
S
S
A
S
P
Site 33
S241
M
D
C
S
P
T
A
S
S
S
A
S
P
G
A
Site 34
S242
D
C
S
P
T
A
S
S
S
A
S
P
G
A
S
Site 35
S243
C
S
P
T
A
S
S
S
A
S
P
G
A
S
T
Site 36
S245
P
T
A
S
S
S
A
S
P
G
A
S
T
T
S
Site 37
S249
S
S
A
S
P
G
A
S
T
T
S
T
P
G
A
Site 38
T251
A
S
P
G
A
S
T
T
S
T
P
G
A
S
P
Site 39
S252
S
P
G
A
S
T
T
S
T
P
G
A
S
P
A
Site 40
T253
P
G
A
S
T
T
S
T
P
G
A
S
P
A
P
Site 41
S257
T
T
S
T
P
G
A
S
P
A
P
R
S
R
K
Site 42
S262
G
A
S
P
A
P
R
S
R
K
P
G
A
V
I
Site 43
S271
K
P
G
A
V
I
E
S
F
V
N
H
A
P
G
Site 44
T287
F
S
G
T
F
S
G
T
L
H
P
N
C
Q
D
Site 45
S296
H
P
N
C
Q
D
S
S
G
R
P
R
R
D
I
Site 46
T305
R
P
R
R
D
I
G
T
I
L
Q
I
L
N
D
Site 47
S315
Q
I
L
N
D
L
L
S
A
T
R
H
Y
Q
G
Site 48
Y320
L
L
S
A
T
R
H
Y
Q
G
M
P
P
S
L
Site 49
S337
L
R
C
H
A
Q
C
S
P
A
S
P
A
P
D
Site 50
S340
H
A
Q
C
S
P
A
S
P
A
P
D
L
A
P
Site 51
T350
P
D
L
A
P
R
T
T
S
C
E
K
L
T
A
Site 52
S351
D
L
A
P
R
T
T
S
C
E
K
L
T
A
A
Site 53
T356
T
T
S
C
E
K
L
T
A
A
P
S
A
S
L
Site 54
S360
E
K
L
T
A
A
P
S
A
S
L
L
Q
G
Q
Site 55
S362
L
T
A
A
P
S
A
S
L
L
Q
G
Q
S
Q
Site 56
S368
A
S
L
L
Q
G
Q
S
Q
I
R
M
C
K
P
Site 57
T383
P
G
D
R
L
R
Q
T
E
N
R
A
T
R
C
Site 58
T388
R
Q
T
E
N
R
A
T
R
C
K
V
E
R
L
Site 59
Y416
R
R
D
A
R
G
P
Y
H
W
S
P
S
R
K
Site 60
S419
A
R
G
P
Y
H
W
S
P
S
R
K
A
G
R
Site 61
S421
G
P
Y
H
W
S
P
S
R
K
A
G
R
S
D
Site 62
S427
P
S
R
K
A
G
R
S
D
S
S
S
S
G
G
Site 63
S429
R
K
A
G
R
S
D
S
S
S
S
G
G
G
G
Site 64
S430
K
A
G
R
S
D
S
S
S
S
G
G
G
G
S
Site 65
S431
A
G
R
S
D
S
S
S
S
G
G
G
G
S
P
Site 66
S432
G
R
S
D
S
S
S
S
G
G
G
G
S
P
S
Site 67
S437
S
S
S
G
G
G
G
S
P
S
E
A
S
G
L
Site 68
S439
S
G
G
G
G
S
P
S
E
A
S
G
L
G
L
Site 69
S451
L
G
L
D
F
E
D
S
V
W
K
P
E
A
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation