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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF585B
Full Name:
Zinc finger protein 585B
Alias:
zinc finger protein 41-like protein
Type:
Mass (Da):
88066
Number AA:
769
UniProt ID:
Q52M93
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
P
A
S
W
T
S
P
Q
K
S
S
A
L
Site 2
S11
S
W
T
S
P
Q
K
S
S
A
L
A
P
E
D
Site 3
S21
L
A
P
E
D
H
G
S
S
Y
E
G
S
V
S
Site 4
S22
A
P
E
D
H
G
S
S
Y
E
G
S
V
S
F
Site 5
Y23
P
E
D
H
G
S
S
Y
E
G
S
V
S
F
R
Site 6
S26
H
G
S
S
Y
E
G
S
V
S
F
R
D
V
A
Site 7
S28
S
S
Y
E
G
S
V
S
F
R
D
V
A
I
D
Site 8
S37
R
D
V
A
I
D
F
S
R
E
E
W
R
H
L
Site 9
S47
E
W
R
H
L
D
L
S
Q
R
N
L
Y
R
D
Site 10
Y52
D
L
S
Q
R
N
L
Y
R
D
V
M
L
E
T
Site 11
T59
Y
R
D
V
M
L
E
T
Y
S
H
L
L
S
V
Site 12
S65
E
T
Y
S
H
L
L
S
V
G
Y
Q
V
P
K
Site 13
Y68
S
H
L
L
S
V
G
Y
Q
V
P
K
P
E
V
Site 14
S95
Q
G
E
R
P
R
H
S
C
P
G
E
K
L
W
Site 15
Y113
Q
H
R
K
I
I
G
Y
K
P
A
S
S
Q
D
Site 16
S117
I
I
G
Y
K
P
A
S
S
Q
D
Q
K
I
Y
Site 17
S118
I
G
Y
K
P
A
S
S
Q
D
Q
K
I
Y
S
Site 18
S125
S
Q
D
Q
K
I
Y
S
G
E
K
S
Y
E
C
Site 19
S129
K
I
Y
S
G
E
K
S
Y
E
C
A
E
F
G
Site 20
Y130
I
Y
S
G
E
K
S
Y
E
C
A
E
F
G
K
Site 21
S143
G
K
S
F
T
W
K
S
Q
F
K
V
H
L
K
Site 22
T179
E
F
I
T
H
Q
K
T
H
M
R
E
K
P
Y
Site 23
Y186
T
H
M
R
E
K
P
Y
K
C
N
E
C
G
K
Site 24
S194
K
C
N
E
C
G
K
S
F
F
Q
V
S
S
L
Site 25
S199
G
K
S
F
F
Q
V
S
S
L
F
R
H
H
R
Site 26
S200
K
S
F
F
Q
V
S
S
L
F
R
H
H
R
I
Site 27
T209
F
R
H
H
R
I
H
T
G
E
K
L
Y
E
C
Site 28
Y214
I
H
T
G
E
K
L
Y
E
C
S
E
C
G
K
Site 29
S217
G
E
K
L
Y
E
C
S
E
C
G
K
G
F
P
Site 30
Y225
E
C
G
K
G
F
P
Y
N
S
D
L
S
I
H
Site 31
S227
G
K
G
F
P
Y
N
S
D
L
S
I
H
E
K
Site 32
S230
F
P
Y
N
S
D
L
S
I
H
E
K
I
H
T
Site 33
T237
S
I
H
E
K
I
H
T
G
E
R
H
H
E
C
Site 34
S255
G
K
A
F
T
Q
K
S
T
L
K
I
H
Q
K
Site 35
T265
K
I
H
Q
K
I
H
T
G
E
R
S
Y
I
C
Site 36
Y270
I
H
T
G
E
R
S
Y
I
C
I
E
C
G
Q
Site 37
S293
I
A
H
R
R
I
H
S
G
E
K
P
Y
E
C
Site 38
Y298
I
H
S
G
E
K
P
Y
E
C
N
N
C
G
K
Site 39
S306
E
C
N
N
C
G
K
S
F
I
S
K
S
Q
L
Site 40
S309
N
C
G
K
S
F
I
S
K
S
Q
L
Q
V
H
Site 41
S311
G
K
S
F
I
S
K
S
Q
L
Q
V
H
Q
R
Site 42
T321
Q
V
H
Q
R
V
H
T
R
V
K
P
Y
I
C
Site 43
Y326
V
H
T
R
V
K
P
Y
I
C
T
E
Y
G
K
Site 44
Y331
K
P
Y
I
C
T
E
Y
G
K
V
F
S
N
N
Site 45
S336
T
E
Y
G
K
V
F
S
N
N
S
N
L
I
T
Site 46
S339
G
K
V
F
S
N
N
S
N
L
I
T
H
E
K
Site 47
T343
S
N
N
S
N
L
I
T
H
E
K
I
Q
S
R
Site 48
S349
I
T
H
E
K
I
Q
S
R
E
K
S
S
I
C
Site 49
S353
K
I
Q
S
R
E
K
S
S
I
C
T
E
C
G
Site 50
T357
R
E
K
S
S
I
C
T
E
C
G
K
A
F
T
Site 51
T364
T
E
C
G
K
A
F
T
Y
R
S
E
L
I
I
Site 52
Y365
E
C
G
K
A
F
T
Y
R
S
E
L
I
I
H
Site 53
S367
G
K
A
F
T
Y
R
S
E
L
I
I
H
Q
R
Site 54
T377
I
I
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 55
Y382
I
H
T
G
E
K
P
Y
E
C
S
D
C
G
R
Site 56
S385
G
E
K
P
Y
E
C
S
D
C
G
R
A
F
T
Site 57
T392
S
D
C
G
R
A
F
T
Q
K
S
A
L
T
V
Site 58
S395
G
R
A
F
T
Q
K
S
A
L
T
V
H
Q
R
Site 59
T398
F
T
Q
K
S
A
L
T
V
H
Q
R
I
H
T
Site 60
T405
T
V
H
Q
R
I
H
T
G
E
K
S
Y
I
C
Site 61
T433
I
T
H
Q
I
I
H
T
G
E
K
P
Y
K
C
Site 62
S451
G
K
L
F
T
S
K
S
Q
L
H
V
H
K
R
Site 63
T461
H
V
H
K
R
I
H
T
G
E
K
P
Y
V
C
Site 64
Y466
I
H
T
G
E
K
P
Y
V
C
N
K
C
G
K
Site 65
T476
N
K
C
G
K
A
F
T
N
R
S
N
L
I
T
Site 66
S479
G
K
A
F
T
N
R
S
N
L
I
T
H
Q
K
Site 67
T483
T
N
R
S
N
L
I
T
H
Q
K
T
H
T
G
Site 68
T487
N
L
I
T
H
Q
K
T
H
T
G
E
K
S
Y
Site 69
T489
I
T
H
Q
K
T
H
T
G
E
K
S
Y
I
C
Site 70
Y494
T
H
T
G
E
K
S
Y
I
C
S
K
C
G
K
Site 71
T504
S
K
C
G
K
A
F
T
Q
R
S
D
L
I
T
Site 72
S507
G
K
A
F
T
Q
R
S
D
L
I
T
H
Q
R
Site 73
T511
T
Q
R
S
D
L
I
T
H
Q
R
I
H
T
G
Site 74
T517
I
T
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 75
Y522
I
H
T
G
E
K
P
Y
E
C
N
T
C
G
K
Site 76
S535
G
K
A
F
T
Q
K
S
N
L
N
I
H
Q
K
Site 77
Y550
I
H
T
G
E
R
Q
Y
E
C
H
E
C
G
K
Site 78
S563
G
K
A
F
N
Q
K
S
I
L
I
V
H
Q
K
Site 79
T573
I
V
H
Q
K
I
H
T
G
E
K
P
Y
V
C
Site 80
Y578
I
H
T
G
E
K
P
Y
V
C
T
E
C
G
R
Site 81
S591
G
R
A
F
I
R
K
S
N
F
I
T
H
Q
R
Site 82
T595
I
R
K
S
N
F
I
T
H
Q
R
I
H
T
G
Site 83
Y606
I
H
T
G
E
K
P
Y
E
C
S
D
C
G
K
Site 84
S609
G
E
K
P
Y
E
C
S
D
C
G
K
S
F
T
Site 85
S614
E
C
S
D
C
G
K
S
F
T
S
K
S
Q
L
Site 86
S617
D
C
G
K
S
F
T
S
K
S
Q
L
L
V
H
Site 87
S619
G
K
S
F
T
S
K
S
Q
L
L
V
H
Q
P
Site 88
T629
L
V
H
Q
P
V
H
T
G
E
K
P
Y
V
C
Site 89
Y634
V
H
T
G
E
K
P
Y
V
C
A
E
C
G
K
Site 90
S644
A
E
C
G
K
A
F
S
G
R
S
N
L
S
K
Site 91
S647
G
K
A
F
S
G
R
S
N
L
S
K
H
Q
K
Site 92
S650
F
S
G
R
S
N
L
S
K
H
Q
K
T
H
T
Site 93
T655
N
L
S
K
H
Q
K
T
H
T
G
E
K
P
Y
Site 94
T657
S
K
H
Q
K
T
H
T
G
E
K
P
Y
I
C
Site 95
Y662
T
H
T
G
E
K
P
Y
I
C
S
E
C
G
K
Site 96
T670
I
C
S
E
C
G
K
T
F
R
Q
K
S
E
L
Site 97
S675
G
K
T
F
R
Q
K
S
E
L
I
T
H
H
R
Site 98
T679
R
Q
K
S
E
L
I
T
H
H
R
I
H
T
G
Site 99
T685
I
T
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 100
S698
E
C
S
D
C
G
K
S
F
T
K
K
S
Q
L
Site 101
S703
G
K
S
F
T
K
K
S
Q
L
Q
V
H
Q
R
Site 102
T713
Q
V
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 103
Y718
I
H
T
G
E
K
P
Y
V
C
A
E
C
G
K
Site 104
S728
A
E
C
G
K
A
F
S
N
R
S
N
L
N
K
Site 105
S731
G
K
A
F
S
N
R
S
N
L
N
K
H
Q
T
Site 106
Y746
T
H
T
G
D
K
P
Y
K
C
G
I
C
G
K
Site 107
S759
G
K
G
F
V
Q
K
S
V
F
S
V
H
Q
S
Site 108
S762
F
V
Q
K
S
V
F
S
V
H
Q
S
S
H
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation