PhosphoNET

           
Protein Info 
   
Short Name:  PDCD4
Full Name:  Programmed cell death protein 4
Alias:  Nuclear antigen H371-like protein; Nuclear antigen H731-like; Protein 197,15a
Type:  Apoptosis protein
Mass (Da):  51721
Number AA:  469
UniProt ID:  Q53EL6
International Prot ID:  IPI00290110
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0005737  GO:0005829 Uniprot OncoNet
Molecular Function:  GO:0003676  GO:0003723  GO:0005488 PhosphoSite+ KinaseNET
Biological Process:  GO:0006469  GO:0006915  GO:0007049 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S20PADPDNLSDSLFSGD
Site 2S22DPDNLSDSLFSGDEE
Site 3S25NLSDSLFSGDEENAG
Site 4T33GDEENAGTEEVKNEI
Site 5S46EINGNWISASSINEA
Site 6S49GNWISASSINEARIN
Site 7S67KRRLRKNSSRDSGRG
Site 8S68RRLRKNSSRDSGRGD
Site 9S71RKNSSRDSGRGDSVS
Site 10S76RDSGRGDSVSDSGSD
Site 11S78SGRGDSVSDSGSDAL
Site 12S80RGDSVSDSGSDALRS
Site 13S82DSVSDSGSDALRSGL
Site 14S87SGSDALRSGLTVPTS
Site 15T90DALRSGLTVPTSPKG
Site 16T93RSGLTVPTSPKGRLL
Site 17S94SGLTVPTSPKGRLLD
Site 18S104GRLLDRRSRSGKGRG
Site 19S106LLDRRSRSGKGRGLP
Site 20T126GGKGVWGTPGQVYDV
Site 21Y131WGTPGQVYDVEEVDV
Site 22Y143VDVKDPNYDDDQENC
Site 23Y152DDQENCVYETVVLPL
Site 24T167DERAFEKTLTPIIQE
Site 25T169RAFEKTLTPIIQEYF
Site 26Y175LTPIIQEYFEHGDTN
Site 27T181EYFEHGDTNEVAEML
Site 28S214LALEGKASHREMTSK
Site 29T219KASHREMTSKLLSDL
Site 30S220ASHREMTSKLLSDLC
Site 31T234CGTVMSTTDVEKSFD
Site 32S239STTDVEKSFDKLLKD
Site 33T277GDGILCNTYIDSYKG
Site 34Y278DGILCNTYIDSYKGT
Site 35Y282CNTYIDSYKGTVDCV
Site 36T285YIDSYKGTVDCVQAR
Site 37S303DKATVLLSMSKGGKR
Site 38S313KGGKRKDSVWGSGGG
Site 39S317RKDSVWGSGGGQQSV
Site 40S323GSGGGQQSVNHLVKE
Site 41S341LLKEYLLSGDISEAE
Site 42S345YLLSGDISEAEHCLK
Site 43S393LLKSLWKSSTITVDQ
Site 44T395KSLWKSSTITVDQMK
Site 45T397LWKSSTITVDQMKRG
Site 46Y405VDQMKRGYERIYNEI
Site 47Y409KRGYERIYNEIPDIN
Site 48S422INLDVPHSYSVLERF
Site 49S424LDVPHSYSVLERFVE
Site 50S440CFQAGIISKQLRDLC
Site 51S449QLRDLCPSRGRKRFV
Site 52S457RGRKRFVSEGDGGRL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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