KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LRRC23
Full Name:
Leucine-rich repeat-containing protein 23
Alias:
Leucine-rich protein B7
Type:
Mass (Da):
39761
Number AA:
343
UniProt ID:
Q53EV4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
D
E
D
D
L
E
D
S
E
P
D
Q
D
D
S
Site 2
S17
S
E
P
D
Q
D
D
S
E
K
E
E
D
E
K
Site 3
Y32
E
T
E
E
G
E
D
Y
R
K
E
G
E
E
F
Site 4
T46
F
P
E
E
W
L
P
T
P
L
T
E
D
M
M
Site 5
T49
E
W
L
P
T
P
L
T
E
D
M
M
K
E
G
Site 6
S58
D
M
M
K
E
G
L
S
L
L
C
K
T
G
N
Site 7
Y71
G
N
G
L
A
H
A
Y
V
K
L
E
V
K
E
Site 8
T82
E
V
K
E
R
D
L
T
D
I
Y
L
L
R
S
Site 9
Y85
E
R
D
L
T
D
I
Y
L
L
R
S
Y
I
H
Site 10
Y90
D
I
Y
L
L
R
S
Y
I
H
L
R
Y
V
D
Site 11
Y95
R
S
Y
I
H
L
R
Y
V
D
I
S
E
N
H
Site 12
S99
H
L
R
Y
V
D
I
S
E
N
H
L
T
D
L
Site 13
T104
D
I
S
E
N
H
L
T
D
L
S
P
L
N
Y
Site 14
S107
E
N
H
L
T
D
L
S
P
L
N
Y
L
T
H
Site 15
S127
A
D
G
N
R
L
R
S
A
Q
M
N
E
L
P
Site 16
T147
S
F
A
Y
N
Q
I
T
D
T
E
G
I
S
H
Site 17
T149
A
Y
N
Q
I
T
D
T
E
G
I
S
H
P
R
Site 18
T159
I
S
H
P
R
L
E
T
L
N
L
K
G
N
S
Site 19
S180
L
D
P
E
K
L
I
S
L
H
T
V
E
L
R
Site 20
T183
E
K
L
I
S
L
H
T
V
E
L
R
G
N
Q
Site 21
T194
R
G
N
Q
L
E
S
T
L
G
I
N
L
P
K
Site 22
Y206
L
P
K
L
K
N
L
Y
L
A
Q
N
M
L
K
Site 23
T226
E
D
L
S
N
L
T
T
L
H
L
R
D
N
Q
Site 24
T236
L
R
D
N
Q
I
D
T
L
S
G
F
S
R
E
Site 25
S238
D
N
Q
I
D
T
L
S
G
F
S
R
E
M
K
Site 26
S246
G
F
S
R
E
M
K
S
L
Q
Y
L
N
L
R
Site 27
Y249
R
E
M
K
S
L
Q
Y
L
N
L
R
G
N
M
Site 28
T283
V
L
L
D
N
P
C
T
D
E
T
S
Y
R
Q
Site 29
T286
D
N
P
C
T
D
E
T
S
Y
R
Q
E
A
L
Site 30
S287
N
P
C
T
D
E
T
S
Y
R
Q
E
A
L
V
Site 31
Y298
E
A
L
V
Q
M
P
Y
L
E
R
L
D
K
E
Site 32
Y307
E
R
L
D
K
E
F
Y
E
E
E
E
R
A
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation