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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACSM3
Full Name:
Acyl-coenzyme A synthetase ACSM3, mitochondrial
Alias:
Acyl-CoA synthetase medium-chain family member 3;Butyrate--CoA ligase 3;Butyryl-coenzyme A synthetase 3;Middle-chain acyl-CoA synthetase 3;Protein SA homolog
Type:
Mass (Da):
66153
Number AA:
586
UniProt ID:
Q53FZ2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
Q
R
L
A
I
F
G
S
V
R
A
L
H
K
D
Site 2
T34
A
L
H
K
D
N
R
T
A
T
P
Q
N
F
S
Site 3
T36
H
K
D
N
R
T
A
T
P
Q
N
F
S
N
Y
Site 4
S41
T
A
T
P
Q
N
F
S
N
Y
E
S
M
K
Q
Site 5
Y43
T
P
Q
N
F
S
N
Y
E
S
M
K
Q
D
F
Site 6
Y57
F
K
L
G
I
P
E
Y
F
N
F
A
K
D
V
Site 7
S96
N
G
E
E
M
R
W
S
F
E
E
L
G
S
L
Site 8
S102
W
S
F
E
E
L
G
S
L
S
R
K
F
A
N
Site 9
S112
R
K
F
A
N
I
L
S
E
A
C
S
L
Q
R
Site 10
S116
N
I
L
S
E
A
C
S
L
Q
R
G
D
R
V
Site 11
T155
I
P
G
T
T
Q
L
T
Q
K
D
I
L
Y
R
Site 12
Y161
L
T
Q
K
D
I
L
Y
R
L
Q
S
S
K
A
Site 13
S186
P
A
V
D
A
V
A
S
K
C
E
N
L
H
S
Site 14
S193
S
K
C
E
N
L
H
S
K
L
I
V
S
E
N
Site 15
S216
K
E
L
M
K
H
A
S
D
S
H
T
C
V
K
Site 16
S218
L
M
K
H
A
S
D
S
H
T
C
V
K
T
K
Site 17
T220
K
H
A
S
D
S
H
T
C
V
K
T
K
H
N
Site 18
Y241
F
T
S
G
T
S
G
Y
P
K
M
T
A
H
T
Site 19
T248
Y
P
K
M
T
A
H
T
H
S
S
F
G
L
G
Site 20
S250
K
M
T
A
H
T
H
S
S
F
G
L
G
L
S
Site 21
S283
S
D
T
G
W
A
K
S
A
W
S
S
V
F
S
Site 22
S310
L
P
R
F
E
P
T
S
I
L
Q
T
L
S
K
Site 23
T314
E
P
T
S
I
L
Q
T
L
S
K
Y
P
I
T
Site 24
Y318
I
L
Q
T
L
S
K
Y
P
I
T
V
F
C
S
Site 25
T339
M
L
V
Q
N
D
I
T
S
Y
K
F
K
S
L
Site 26
S340
L
V
Q
N
D
I
T
S
Y
K
F
K
S
L
K
Site 27
Y341
V
Q
N
D
I
T
S
Y
K
F
K
S
L
K
H
Site 28
S345
I
T
S
Y
K
F
K
S
L
K
H
C
V
S
A
Site 29
T357
V
S
A
G
E
P
I
T
P
D
V
T
E
K
W
Site 30
T361
E
P
I
T
P
D
V
T
E
K
W
R
N
K
T
Site 31
T368
T
E
K
W
R
N
K
T
G
L
D
I
Y
E
G
Site 32
Y373
N
K
T
G
L
D
I
Y
E
G
Y
G
Q
T
E
Site 33
T381
E
G
Y
G
Q
T
E
T
V
L
I
C
G
N
F
Site 34
S397
G
M
K
I
K
P
G
S
M
G
K
P
S
P
A
Site 35
S402
P
G
S
M
G
K
P
S
P
A
F
D
V
K
I
Site 36
Y441
P
F
G
L
F
T
H
Y
V
D
N
P
S
K
T
Site 37
S446
T
H
Y
V
D
N
P
S
K
T
A
S
T
L
R
Site 38
S450
D
N
P
S
K
T
A
S
T
L
R
G
N
F
Y
Site 39
T451
N
P
S
K
T
A
S
T
L
R
G
N
F
Y
I
Site 40
Y457
S
T
L
R
G
N
F
Y
I
T
G
D
R
G
Y
Site 41
Y464
Y
I
T
G
D
R
G
Y
M
D
K
D
G
Y
F
Site 42
Y470
G
Y
M
D
K
D
G
Y
F
W
F
V
A
R
A
Site 43
Y486
D
V
I
L
S
S
G
Y
R
I
G
P
F
E
V
Site 44
S502
N
A
L
N
E
H
P
S
V
A
E
S
A
V
V
Site 45
S506
E
H
P
S
V
A
E
S
A
V
V
S
S
P
D
Site 46
S511
A
E
S
A
V
V
S
S
P
D
P
I
R
G
E
Site 47
Y530
F
V
V
L
N
P
D
Y
K
S
H
D
Q
E
Q
Site 48
S532
V
L
N
P
D
Y
K
S
H
D
Q
E
Q
L
I
Site 49
Y553
V
K
K
T
T
A
P
Y
K
Y
P
R
K
V
E
Site 50
Y555
K
T
T
A
P
Y
K
Y
P
R
K
V
E
F
I
Site 51
T568
F
I
Q
E
L
P
K
T
I
S
G
K
T
K
R
Site 52
S570
Q
E
L
P
K
T
I
S
G
K
T
K
R
N
E
Site 53
T573
P
K
T
I
S
G
K
T
K
R
N
E
L
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation