KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PDLIM3
Full Name:
PDZ and LIM domain protein 3
Alias:
actinin-associated LIM; ALP; alpha-actinin-2-associated LIM; enigma; PDLI3; PDZ and LIM domain 3
Type:
Cytoskeletal protein
Mass (Da):
39232
Number AA:
364
UniProt ID:
Q53GG5
International Prot ID:
IPI00004471
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030018
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
A
P
W
G
F
R
L
S
G
G
I
D
F
N
Q
Site 2
S59
I
D
G
F
G
T
E
S
M
T
H
A
D
A
Q
Site 3
T85
L
K
I
D
R
G
E
T
H
L
W
S
P
Q
V
Site 4
S89
R
G
E
T
H
L
W
S
P
Q
V
S
E
D
G
Site 5
S93
H
L
W
S
P
Q
V
S
E
D
G
K
A
H
P
Site 6
S107
P
F
K
I
N
L
E
S
E
P
Q
D
G
N
Y
Site 7
Y114
S
E
P
Q
D
G
N
Y
F
E
H
K
H
N
I
Site 8
S132
P
F
V
I
P
G
R
S
S
G
C
S
T
P
S
Site 9
S133
F
V
I
P
G
R
S
S
G
C
S
T
P
S
G
Site 10
S136
P
G
R
S
S
G
C
S
T
P
S
G
I
D
C
Site 11
T137
G
R
S
S
G
C
S
T
P
S
G
I
D
C
G
Site 12
S139
S
S
G
C
S
T
P
S
G
I
D
C
G
S
G
Site 13
S145
P
S
G
I
D
C
G
S
G
R
S
T
P
S
S
Site 14
S148
I
D
C
G
S
G
R
S
T
P
S
S
V
S
T
Site 15
T149
D
C
G
S
G
R
S
T
P
S
S
V
S
T
V
Site 16
S151
G
S
G
R
S
T
P
S
S
V
S
T
V
S
T
Site 17
S152
S
G
R
S
T
P
S
S
V
S
T
V
S
T
I
Site 18
S154
R
S
T
P
S
S
V
S
T
V
S
T
I
C
P
Site 19
T192
I
V
H
A
Q
F
N
T
P
M
Q
L
Y
S
D
Site 20
Y197
F
N
T
P
M
Q
L
Y
S
D
D
N
I
M
E
Site 21
T205
S
D
D
N
I
M
E
T
L
Q
G
Q
V
S
T
Site 22
T217
V
S
T
A
L
G
E
T
P
L
M
S
E
P
T
Site 23
S221
L
G
E
T
P
L
M
S
E
P
T
A
S
V
P
Site 24
T224
T
P
L
M
S
E
P
T
A
S
V
P
P
E
S
Site 25
S226
L
M
S
E
P
T
A
S
V
P
P
E
S
D
V
Site 26
S231
T
A
S
V
P
P
E
S
D
V
Y
R
M
L
H
Site 27
Y234
V
P
P
E
S
D
V
Y
R
M
L
H
D
N
R
Site 28
T245
H
D
N
R
N
E
P
T
Q
P
R
Q
S
G
S
Site 29
S250
E
P
T
Q
P
R
Q
S
G
S
F
R
V
L
Q
Site 30
S252
T
Q
P
R
Q
S
G
S
F
R
V
L
Q
G
M
Site 31
S264
Q
G
M
V
D
D
G
S
D
D
R
P
A
G
T
Site 32
S273
D
R
P
A
G
T
R
S
V
R
A
P
V
T
K
Site 33
T279
R
S
V
R
A
P
V
T
K
V
H
G
G
S
G
Site 34
S299
P
L
C
D
K
C
G
S
G
I
V
G
A
V
V
Site 35
Y312
V
V
K
A
R
D
K
Y
R
H
P
E
C
F
V
Site 36
Y332
L
N
L
K
Q
K
G
Y
F
F
I
E
G
E
L
Site 37
Y340
F
F
I
E
G
E
L
Y
C
E
T
H
A
R
A
Site 38
T349
E
T
H
A
R
A
R
T
K
P
P
E
G
Y
D
Site 39
Y355
R
T
K
P
P
E
G
Y
D
T
V
T
L
Y
P
Site 40
T357
K
P
P
E
G
Y
D
T
V
T
L
Y
P
K
A
Site 41
T359
P
E
G
Y
D
T
V
T
L
Y
P
K
A
_
_
Site 42
Y361
G
Y
D
T
V
T
L
Y
P
K
A
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation