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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
USP39
Full Name:
U4/U6.U5 tri-snRNP-associated protein 2
Alias:
CGI-21; HSPC332; MGC75069; SAD1; SNUT2; U4/U6.U5 tri-snRNP-associated 65 kDa protein; U4/U6.U5 tri-snRNP-associated protein 2
Type:
Mass (Da):
65381
Number AA:
565
UniProt ID:
Q53GS9
International Prot ID:
IPI00419844
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004221
GO:0004843
PhosphoSite+
KinaseNET
Biological Process:
GO:0000245
GO:0006139
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
G
R
S
K
R
E
S
R
G
S
Site 2
S9
S
G
R
S
K
R
E
S
R
G
S
T
R
G
K
Site 3
S12
S
K
R
E
S
R
G
S
T
R
G
K
R
E
S
Site 4
T13
K
R
E
S
R
G
S
T
R
G
K
R
E
S
E
Site 5
S19
S
T
R
G
K
R
E
S
E
S
R
G
S
S
G
Site 6
S21
R
G
K
R
E
S
E
S
R
G
S
S
G
R
V
Site 7
S24
R
E
S
E
S
R
G
S
S
G
R
V
K
R
E
Site 8
S25
E
S
E
S
R
G
S
S
G
R
V
K
R
E
R
Site 9
S42
E
R
E
P
E
A
A
S
S
R
G
S
P
V
R
Site 10
S43
R
E
P
E
A
A
S
S
R
G
S
P
V
R
V
Site 11
S46
E
A
A
S
S
R
G
S
P
V
R
V
K
R
E
Site 12
S58
K
R
E
F
E
P
A
S
A
R
E
A
P
A
S
Site 13
S82
E
R
E
V
D
E
D
S
E
P
E
R
E
V
R
Site 14
S97
A
K
N
G
R
V
D
S
E
D
R
R
S
R
H
Site 15
S102
V
D
S
E
D
R
R
S
R
H
C
P
Y
L
D
Site 16
Y107
R
R
S
R
H
C
P
Y
L
D
T
I
N
R
S
Site 17
T110
R
H
C
P
Y
L
D
T
I
N
R
S
V
L
D
Site 18
S114
Y
L
D
T
I
N
R
S
V
L
D
F
D
F
E
Site 19
S150
F
Q
G
R
G
L
K
S
H
A
Y
I
H
S
V
Site 20
Y153
R
G
L
K
S
H
A
Y
I
H
S
V
Q
F
S
Site 21
Y173
N
L
H
T
L
K
F
Y
C
L
P
D
N
Y
E
Site 22
Y179
F
Y
C
L
P
D
N
Y
E
I
I
D
S
S
L
Site 23
S184
D
N
Y
E
I
I
D
S
S
L
E
D
I
T
Y
Site 24
S185
N
Y
E
I
I
D
S
S
L
E
D
I
T
Y
V
Site 25
T190
D
S
S
L
E
D
I
T
Y
V
L
K
P
T
F
Site 26
Y191
S
S
L
E
D
I
T
Y
V
L
K
P
T
F
T
Site 27
Y215
Q
A
K
L
S
R
A
Y
D
G
T
T
Y
L
P
Site 28
T219
S
R
A
Y
D
G
T
T
Y
L
P
G
I
V
G
Site 29
Y235
N
N
I
K
A
N
D
Y
A
N
A
V
L
Q
A
Site 30
S244
N
A
V
L
Q
A
L
S
N
V
P
P
L
R
N
Site 31
Y252
N
V
P
P
L
R
N
Y
F
L
E
E
D
N
Y
Site 32
Y259
Y
F
L
E
E
D
N
Y
K
N
I
K
R
P
P
Site 33
S295
R
N
F
K
A
H
V
S
P
H
E
M
L
Q
A
Site 34
T310
V
V
L
C
S
K
K
T
F
Q
I
T
K
Q
G
Site 35
S332
W
F
L
N
A
L
H
S
A
L
G
G
T
K
K
Site 36
S352
V
T
D
V
F
Q
G
S
M
R
I
F
T
K
K
Site 37
T357
Q
G
S
M
R
I
F
T
K
K
L
P
H
P
D
Site 38
Y379
Q
L
L
H
N
D
E
Y
Q
E
T
M
V
E
S
Site 39
T387
Q
E
T
M
V
E
S
T
F
M
Y
L
T
L
D
Site 40
Y401
D
L
P
T
A
P
L
Y
K
D
E
K
E
Q
L
Site 41
Y430
N
G
I
T
E
K
E
Y
K
T
Y
K
E
N
F
Site 42
Y433
T
E
K
E
Y
K
T
Y
K
E
N
F
L
K
R
Site 43
Y483
T
N
V
D
L
R
E
Y
L
S
E
E
V
Q
A
Site 44
S485
V
D
L
R
E
Y
L
S
E
E
V
Q
A
V
H
Site 45
S513
D
G
K
P
S
E
G
S
Y
R
I
H
V
L
H
Site 46
Y514
G
K
P
S
E
G
S
Y
R
I
H
V
L
H
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation