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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGK
Full Name:
Acylglycerol kinase, mitochondrial
Alias:
Acylglycerol kinase; FLJ10842; MULK; Multiple substrate lipid kinase
Type:
EC 2.7.1.107; EC 2.7.1.94; Lipid Metabolism - glycerolipid; Kinase, lipid
Mass (Da):
47119
Number AA:
422
UniProt ID:
Q53H12
International Prot ID:
IPI00019353
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031966
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0047620
GO:0004143
PhosphoSite+
KinaseNET
Biological Process:
GO:0007205
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T96
H
L
S
G
M
D
V
T
I
V
K
T
D
Y
E
Site 2
Y102
V
T
I
V
K
T
D
Y
E
G
Q
A
K
K
L
Site 3
T139
V
T
G
V
L
R
R
T
D
E
A
T
F
S
K
Site 4
T143
L
R
R
T
D
E
A
T
F
S
K
I
P
I
G
Site 5
S145
R
T
D
E
A
T
F
S
K
I
P
I
G
F
I
Site 6
S161
L
G
E
T
S
S
L
S
H
T
L
F
A
E
S
Site 7
T163
E
T
S
S
L
S
H
T
L
F
A
E
S
G
N
Site 8
S213
M
T
G
L
R
W
G
S
F
R
D
A
G
V
K
Site 9
Y224
A
G
V
K
V
S
K
Y
W
Y
L
G
P
L
K
Site 10
Y226
V
K
V
S
K
Y
W
Y
L
G
P
L
K
I
K
Site 11
T247
T
L
K
E
W
P
Q
T
H
Q
A
S
I
S
Y
Site 12
S253
Q
T
H
Q
A
S
I
S
Y
T
G
P
T
E
R
Site 13
Y254
T
H
Q
A
S
I
S
Y
T
G
P
T
E
R
P
Site 14
T255
H
Q
A
S
I
S
Y
T
G
P
T
E
R
P
P
Site 15
T258
S
I
S
Y
T
G
P
T
E
R
P
P
N
E
P
Site 16
T268
P
P
N
E
P
E
E
T
P
V
Q
R
P
S
L
Site 17
S274
E
T
P
V
Q
R
P
S
L
Y
R
R
I
L
R
Site 18
Y276
P
V
Q
R
P
S
L
Y
R
R
I
L
R
R
L
Site 19
S285
R
I
L
R
R
L
A
S
Y
W
A
Q
P
Q
D
Site 20
Y286
I
L
R
R
L
A
S
Y
W
A
Q
P
Q
D
A
Site 21
S295
A
Q
P
Q
D
A
L
S
Q
E
V
S
P
E
V
Site 22
S299
D
A
L
S
Q
E
V
S
P
E
V
W
K
D
V
Site 23
T316
S
T
I
E
L
S
I
T
T
R
N
N
Q
L
D
Site 24
T317
T
I
E
L
S
I
T
T
R
N
N
Q
L
D
P
Site 25
T325
R
N
N
Q
L
D
P
T
S
K
E
D
F
L
N
Site 26
S326
N
N
Q
L
D
P
T
S
K
E
D
F
L
N
I
Site 27
S382
I
P
E
G
A
G
G
S
F
S
I
D
S
E
E
Site 28
S384
E
G
A
G
G
S
F
S
I
D
S
E
E
Y
E
Site 29
S387
G
G
S
F
S
I
D
S
E
E
Y
E
A
M
P
Site 30
T421
E
Q
M
L
T
S
P
T
Q
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation