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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL26
Full Name:
Kelch-like protein 26
Alias:
Type:
Mass (Da):
68139
Number AA:
615
UniProt ID:
Q53HC5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
E
S
G
G
S
S
G
G
A
G
G
G
Site 2
S8
M
A
E
S
G
G
S
S
G
G
A
G
G
G
G
Site 3
S28
P
G
P
E
R
P
N
S
T
A
D
K
N
G
A
Site 4
T39
K
N
G
A
L
K
C
T
F
S
A
P
S
H
S
Site 5
S41
G
A
L
K
C
T
F
S
A
P
S
H
S
T
S
Site 6
S44
K
C
T
F
S
A
P
S
H
S
T
S
L
L
Q
Site 7
S46
T
F
S
A
P
S
H
S
T
S
L
L
Q
G
L
Site 8
S48
S
A
P
S
H
S
T
S
L
L
Q
G
L
A
T
Site 9
T68
Q
L
L
D
V
V
L
T
I
N
R
E
A
F
P
Site 10
S100
T
G
G
M
R
E
A
S
Q
D
V
I
E
L
K
Site 11
S176
G
Q
M
A
T
T
F
S
L
A
S
L
R
E
S
Site 12
S183
S
L
A
S
L
R
E
S
V
D
A
F
T
F
R
Site 13
T188
R
E
S
V
D
A
F
T
F
R
H
F
L
Q
I
Site 14
S220
L
Q
S
N
R
L
Q
S
C
A
E
I
D
L
F
Site 15
S245
P
A
R
R
P
R
A
S
H
V
L
C
H
I
R
Site 16
S259
R
F
P
L
M
Q
S
S
E
L
V
D
S
V
Q
Site 17
S264
Q
S
S
E
L
V
D
S
V
Q
T
L
D
I
M
Site 18
Y280
E
D
V
L
C
R
Q
Y
L
L
E
A
F
N
Y
Site 19
Y287
Y
L
L
E
A
F
N
Y
Q
V
L
P
F
R
Q
Site 20
S299
F
R
Q
H
E
M
Q
S
P
R
T
A
V
R
S
Site 21
T302
H
E
M
Q
S
P
R
T
A
V
R
S
D
V
P
Site 22
S306
S
P
R
T
A
V
R
S
D
V
P
S
L
V
T
Site 23
T317
S
L
V
T
F
G
G
T
P
Y
T
D
S
D
R
Site 24
T320
T
F
G
G
T
P
Y
T
D
S
D
R
S
V
S
Site 25
S322
G
G
T
P
Y
T
D
S
D
R
S
V
S
S
K
Site 26
S325
P
Y
T
D
S
D
R
S
V
S
S
K
V
Y
Q
Site 27
S327
T
D
S
D
R
S
V
S
S
K
V
Y
Q
L
P
Site 28
Y331
R
S
V
S
S
K
V
Y
Q
L
P
E
P
G
A
Site 29
T345
A
R
H
F
R
E
L
T
E
M
E
V
G
C
S
Site 30
Y373
A
G
G
Q
H
L
Q
Y
R
S
G
E
G
A
V
Site 31
Y384
E
G
A
V
D
A
C
Y
R
Y
D
P
H
L
N
Site 32
Y386
A
V
D
A
C
Y
R
Y
D
P
H
L
N
R
W
Site 33
Y416
N
V
L
C
G
M
V
Y
A
T
G
G
R
N
R
Site 34
S426
G
G
R
N
R
A
G
S
L
A
S
V
E
R
Y
Site 35
S429
N
R
A
G
S
L
A
S
V
E
R
Y
C
P
R
Site 36
Y433
S
L
A
S
V
E
R
Y
C
P
R
R
N
E
W
Site 37
Y442
P
R
R
N
E
W
G
Y
A
C
S
L
K
R
R
Site 38
T450
A
C
S
L
K
R
R
T
W
G
H
A
G
A
A
Site 39
S458
W
G
H
A
G
A
A
S
G
G
R
L
Y
I
S
Site 40
S471
I
S
G
G
Y
G
I
S
V
E
D
K
K
A
L
Site 41
Y481
D
K
K
A
L
H
C
Y
D
P
V
A
D
Q
W
Site 42
S495
W
E
F
K
A
P
M
S
E
P
R
V
L
H
A
Site 43
Y531
F
D
V
L
A
V
E
Y
Y
V
P
E
T
D
Q
Site 44
Y532
D
V
L
A
V
E
Y
Y
V
P
E
T
D
Q
W
Site 45
T536
V
E
Y
Y
V
P
E
T
D
Q
W
T
S
V
S
Site 46
S541
P
E
T
D
Q
W
T
S
V
S
P
M
R
A
G
Site 47
S543
T
D
Q
W
T
S
V
S
P
M
R
A
G
Q
S
Site 48
Y581
V
T
G
I
V
Q
V
Y
N
T
D
T
D
E
W
Site 49
T585
V
Q
V
Y
N
T
D
T
D
E
W
E
R
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation