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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ANKRD57
Full Name:
Ankyrin repeat domain-containing protein 57
Alias:
ANR57; C2orf26; chromosome 2 open reading frame 26; LOC65124
Type:
Uncharacterized
Mass (Da):
55672
Number AA:
525
UniProt ID:
Q53LP3
International Prot ID:
IPI00253323
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y76
D
P
A
D
G
A
K
Y
V
H
L
K
K
R
F
Site 2
S88
K
R
F
C
E
G
P
S
E
P
S
G
D
P
P
Site 3
T100
D
P
P
R
I
Q
V
T
A
E
P
E
A
P
D
Site 4
S126
P
D
A
A
A
P
E
S
L
P
G
Q
G
R
E
Site 5
S149
P
A
H
W
P
P
L
S
A
G
A
R
R
K
N
Site 6
S157
A
G
A
R
R
K
N
S
R
R
D
V
Q
P
L
Site 7
T167
D
V
Q
P
L
P
R
T
P
A
P
G
P
S
E
Site 8
S173
R
T
P
A
P
G
P
S
E
D
L
E
L
P
P
Site 9
S190
C
E
E
A
D
R
G
S
S
L
V
G
A
T
A
Site 10
S191
E
E
A
D
R
G
S
S
L
V
G
A
T
A
Q
Site 11
S212
L
R
D
L
V
M
G
S
S
P
Q
L
K
R
S
Site 12
S213
R
D
L
V
M
G
S
S
P
Q
L
K
R
S
V
Site 13
S219
S
S
P
Q
L
K
R
S
V
C
P
G
G
S
S
Site 14
S225
R
S
V
C
P
G
G
S
S
P
G
S
S
S
G
Site 15
S226
S
V
C
P
G
G
S
S
P
G
S
S
S
G
G
Site 16
S229
P
G
G
S
S
P
G
S
S
S
G
G
G
R
G
Site 17
S230
G
G
S
S
P
G
S
S
S
G
G
G
R
G
R
Site 18
S231
G
S
S
P
G
S
S
S
G
G
G
R
G
R
G
Site 19
S242
R
G
R
G
G
G
D
S
D
S
A
S
V
A
S
Site 20
S244
R
G
G
G
D
S
D
S
A
S
V
A
S
S
S
Site 21
S246
G
G
D
S
D
S
A
S
V
A
S
S
S
A
E
Site 22
S250
D
S
A
S
V
A
S
S
S
A
E
E
E
S
S
Site 23
S251
S
A
S
V
A
S
S
S
A
E
E
E
S
S
G
Site 24
S256
S
S
S
A
E
E
E
S
S
G
G
G
S
V
T
Site 25
S257
S
S
A
E
E
E
S
S
G
G
G
S
V
T
L
Site 26
S261
E
E
S
S
G
G
G
S
V
T
L
D
P
L
E
Site 27
T263
S
S
G
G
G
S
V
T
L
D
P
L
E
H
A
Site 28
S276
H
A
W
M
L
S
A
S
D
G
K
W
D
S
L
Site 29
S282
A
S
D
G
K
W
D
S
L
E
G
L
L
T
C
Site 30
S339
V
N
I
D
A
R
T
S
G
G
Y
T
A
L
H
Site 31
Y342
D
A
R
T
S
G
G
Y
T
A
L
H
L
A
A
Site 32
Y373
A
D
V
D
I
R
D
Y
S
G
K
K
A
S
Q
Site 33
S374
D
V
D
I
R
D
Y
S
G
K
K
A
S
Q
Y
Site 34
S379
D
Y
S
G
K
K
A
S
Q
Y
L
S
R
S
I
Site 35
Y381
S
G
K
K
A
S
Q
Y
L
S
R
S
I
A
E
Site 36
S383
K
K
A
S
Q
Y
L
S
R
S
I
A
E
E
I
Site 37
S404
L
D
E
G
D
G
E
S
A
A
G
S
G
G
G
Site 38
S408
D
G
E
S
A
A
G
S
G
G
G
R
W
R
L
Site 39
S416
G
G
G
R
W
R
L
S
K
V
L
P
S
H
L
Site 40
Y426
L
P
S
H
L
I
T
Y
K
L
S
H
A
L
E
Site 41
S429
H
L
I
T
Y
K
L
S
H
A
L
E
D
G
G
Site 42
S461
K
D
P
G
R
K
A
S
G
S
S
S
G
R
I
Site 43
S463
P
G
R
K
A
S
G
S
S
S
G
R
I
K
P
Site 44
S465
R
K
A
S
G
S
S
S
G
R
I
K
P
R
L
Site 45
T479
L
N
K
I
R
F
R
T
Q
I
V
H
T
T
P
Site 46
T485
R
T
Q
I
V
H
T
T
P
S
F
R
D
P
E
Site 47
S487
Q
I
V
H
T
T
P
S
F
R
D
P
E
Q
P
Site 48
S513
E
R
P
V
K
G
H
S
P
F
T
L
R
P
K
Site 49
T516
V
K
G
H
S
P
F
T
L
R
P
K
S
N
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation