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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARHGAP15
Full Name:
Rho GTPase-activating protein 15
Alias:
ArhGAP15;Rho-type GTPase-activating protein 15
Type:
Mass (Da):
54544
Number AA:
475
UniProt ID:
Q53QZ3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
Q
K
S
T
N
S
D
T
S
V
E
T
L
Site 2
T9
Q
K
S
T
N
S
D
T
S
V
E
T
L
N
S
Site 3
S10
K
S
T
N
S
D
T
S
V
E
T
L
N
S
T
Site 4
T13
N
S
D
T
S
V
E
T
L
N
S
T
R
Q
G
Site 5
S16
T
S
V
E
T
L
N
S
T
R
Q
G
T
G
A
Site 6
T21
L
N
S
T
R
Q
G
T
G
A
V
Q
M
R
I
Site 7
S33
M
R
I
K
N
A
N
S
H
H
D
R
L
S
Q
Site 8
S39
N
S
H
H
D
R
L
S
Q
S
K
S
M
I
L
Site 9
S41
H
H
D
R
L
S
Q
S
K
S
M
I
L
T
D
Site 10
S43
D
R
L
S
Q
S
K
S
M
I
L
T
D
V
G
Site 11
T47
Q
S
K
S
M
I
L
T
D
V
G
K
V
T
E
Site 12
T53
L
T
D
V
G
K
V
T
E
P
I
S
R
H
R
Site 13
S57
G
K
V
T
E
P
I
S
R
H
R
R
N
H
S
Site 14
S64
S
R
H
R
R
N
H
S
Q
H
I
L
K
D
V
Site 15
Y85
L
M
V
E
K
E
G
Y
L
Q
K
A
K
I
A
Site 16
S103
K
K
L
R
K
N
W
S
T
S
W
I
V
L
S
Site 17
T104
K
L
R
K
N
W
S
T
S
W
I
V
L
S
S
Site 18
S105
L
R
K
N
W
S
T
S
W
I
V
L
S
S
R
Site 19
S110
S
T
S
W
I
V
L
S
S
R
R
I
E
F
Y
Site 20
S111
T
S
W
I
V
L
S
S
R
R
I
E
F
Y
K
Site 21
Y117
S
S
R
R
I
E
F
Y
K
E
S
K
Q
Q
A
Site 22
S120
R
I
E
F
Y
K
E
S
K
Q
Q
A
L
S
N
Site 23
S126
E
S
K
Q
Q
A
L
S
N
M
K
T
G
H
K
Site 24
T130
Q
A
L
S
N
M
K
T
G
H
K
P
E
S
V
Site 25
S136
K
T
G
H
K
P
E
S
V
D
L
C
G
A
H
Site 26
S151
I
E
W
A
K
E
K
S
S
R
K
N
V
F
Q
Site 27
S195
I
D
R
L
P
K
D
S
S
C
P
S
R
N
L
Site 28
S196
D
R
L
P
K
D
S
S
C
P
S
R
N
L
E
Site 29
S199
P
K
D
S
S
C
P
S
R
N
L
E
L
F
K
Site 30
S210
E
L
F
K
I
Q
R
S
S
S
T
E
L
L
S
Site 31
S211
L
F
K
I
Q
R
S
S
S
T
E
L
L
S
H
Site 32
S212
F
K
I
Q
R
S
S
S
T
E
L
L
S
H
Y
Site 33
T213
K
I
Q
R
S
S
S
T
E
L
L
S
H
Y
D
Site 34
S217
S
S
S
T
E
L
L
S
H
Y
D
S
D
I
K
Site 35
Y219
S
T
E
L
L
S
H
Y
D
S
D
I
K
E
Q
Site 36
S221
E
L
L
S
H
Y
D
S
D
I
K
E
Q
K
P
Site 37
S233
Q
K
P
E
H
R
K
S
L
M
F
R
L
H
H
Site 38
S241
L
M
F
R
L
H
H
S
A
S
D
T
S
D
K
Site 39
S243
F
R
L
H
H
S
A
S
D
T
S
D
K
N
R
Site 40
T245
L
H
H
S
A
S
D
T
S
D
K
N
R
V
K
Site 41
S253
S
D
K
N
R
V
K
S
R
L
K
K
F
I
T
Site 42
T260
S
R
L
K
K
F
I
T
R
R
P
S
L
K
T
Site 43
S264
K
F
I
T
R
R
P
S
L
K
T
L
Q
E
K
Site 44
T267
T
R
R
P
S
L
K
T
L
Q
E
K
G
L
I
Site 45
S292
K
V
C
E
R
E
N
S
T
V
P
W
F
V
K
Site 46
T324
R
V
S
G
N
L
A
T
I
Q
K
L
R
F
I
Site 47
S343
E
K
L
N
L
D
D
S
Q
W
E
D
I
H
V
Site 48
S370
P
E
P
L
F
P
Y
S
F
F
E
Q
F
V
E
Site 49
S393
T
R
I
E
A
V
K
S
L
V
Q
K
L
P
P
Site 50
T405
L
P
P
P
N
R
D
T
M
K
V
L
F
G
H
Site 51
S421
T
K
I
V
A
K
A
S
K
N
L
M
S
T
Q
Site 52
T445
L
L
R
A
E
N
E
T
G
N
M
A
I
H
M
Site 53
Y466
A
E
L
M
L
S
E
Y
S
K
I
F
G
S
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation