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Updated November 2019
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Protein Info
Short Name:
C2orf53
Full Name:
Uncharacterized protein C2orf53
Alias:
Type:
Mass (Da):
44690
Number AA:
412
UniProt ID:
Q53SZ7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
D
Q
V
L
P
Q
T
S
V
L
P
G
R
P
T
Site 2
S25
G
R
P
T
W
G
F
S
Q
L
V
D
S
S
P
Site 3
S30
G
F
S
Q
L
V
D
S
S
P
H
N
L
Q
P
Site 4
S31
F
S
Q
L
V
D
S
S
P
H
N
L
Q
P
L
Site 5
S39
P
H
N
L
Q
P
L
S
P
H
Q
G
L
P
P
Site 6
S47
P
H
Q
G
L
P
P
S
Q
P
P
F
S
S
T
Site 7
S52
P
P
S
Q
P
P
F
S
S
T
Q
S
R
R
P
Site 8
S53
P
S
Q
P
P
F
S
S
T
Q
S
R
R
P
S
Site 9
T54
S
Q
P
P
F
S
S
T
Q
S
R
R
P
S
S
Site 10
S56
P
P
F
S
S
T
Q
S
R
R
P
S
S
P
P
Site 11
S60
S
T
Q
S
R
R
P
S
S
P
P
P
A
S
P
Site 12
S61
T
Q
S
R
R
P
S
S
P
P
P
A
S
P
S
Site 13
S66
P
S
S
P
P
P
A
S
P
S
P
G
F
Q
F
Site 14
S68
S
P
P
P
A
S
P
S
P
G
F
Q
F
G
S
Site 15
S75
S
P
G
F
Q
F
G
S
C
D
S
N
S
D
F
Site 16
S78
F
Q
F
G
S
C
D
S
N
S
D
F
A
P
H
Site 17
S80
F
G
S
C
D
S
N
S
D
F
A
P
H
P
Y
Site 18
Y87
S
D
F
A
P
H
P
Y
S
P
S
L
P
S
S
Site 19
S88
D
F
A
P
H
P
Y
S
P
S
L
P
S
S
P
Site 20
S90
A
P
H
P
Y
S
P
S
L
P
S
S
P
T
F
Site 21
S93
P
Y
S
P
S
L
P
S
S
P
T
F
F
H
Q
Site 22
S94
Y
S
P
S
L
P
S
S
P
T
F
F
H
Q
N
Site 23
T96
P
S
L
P
S
S
P
T
F
F
H
Q
N
Y
L
Site 24
Y102
P
T
F
F
H
Q
N
Y
L
S
L
P
R
P
R
Site 25
S104
F
F
H
Q
N
Y
L
S
L
P
R
P
R
A
S
Site 26
S111
S
L
P
R
P
R
A
S
S
P
S
N
H
W
L
Site 27
S112
L
P
R
P
R
A
S
S
P
S
N
H
W
L
Y
Site 28
S114
R
P
R
A
S
S
P
S
N
H
W
L
Y
P
S
Site 29
Y119
S
P
S
N
H
W
L
Y
P
S
P
P
L
T
P
Site 30
S121
S
N
H
W
L
Y
P
S
P
P
L
T
P
S
F
Site 31
T125
L
Y
P
S
P
P
L
T
P
S
F
S
P
S
Q
Site 32
S127
P
S
P
P
L
T
P
S
F
S
P
S
Q
P
Q
Site 33
S129
P
P
L
T
P
S
F
S
P
S
Q
P
Q
N
S
Site 34
S131
L
T
P
S
F
S
P
S
Q
P
Q
N
S
S
L
Site 35
S136
S
P
S
Q
P
Q
N
S
S
L
P
H
S
P
C
Site 36
S137
P
S
Q
P
Q
N
S
S
L
P
H
S
P
C
Q
Site 37
S141
Q
N
S
S
L
P
H
S
P
C
Q
S
P
S
H
Site 38
S145
L
P
H
S
P
C
Q
S
P
S
H
P
E
E
L
Site 39
S147
H
S
P
C
Q
S
P
S
H
P
E
E
L
H
S
Site 40
S154
S
H
P
E
E
L
H
S
S
T
L
T
S
P
G
Site 41
S155
H
P
E
E
L
H
S
S
T
L
T
S
P
G
P
Site 42
T156
P
E
E
L
H
S
S
T
L
T
S
P
G
P
S
Site 43
T158
E
L
H
S
S
T
L
T
S
P
G
P
S
P
P
Site 44
S159
L
H
S
S
T
L
T
S
P
G
P
S
P
P
S
Site 45
S163
T
L
T
S
P
G
P
S
P
P
S
H
R
L
H
Site 46
S166
S
P
G
P
S
P
P
S
H
R
L
H
S
N
R
Site 47
T184
R
W
H
Q
Y
R
D
T
G
S
G
S
P
G
V
Site 48
S186
H
Q
Y
R
D
T
G
S
G
S
P
G
V
V
E
Site 49
S188
Y
R
D
T
G
S
G
S
P
G
V
V
E
R
C
Site 50
S260
L
V
C
L
R
P
R
S
P
S
C
P
L
P
R
Site 51
S262
C
L
R
P
R
S
P
S
C
P
L
P
R
Y
R
Site 52
Y268
P
S
C
P
L
P
R
Y
R
T
G
P
R
L
L
Site 53
T270
C
P
L
P
R
Y
R
T
G
P
R
L
L
A
F
Site 54
T328
A
G
P
Q
G
K
A
T
Q
A
C
G
H
Q
L
Site 55
S338
C
G
H
Q
L
P
A
S
Q
P
P
A
A
Q
A
Site 56
T353
R
A
D
P
V
P
G
T
P
S
Q
T
R
S
F
Site 57
S355
D
P
V
P
G
T
P
S
Q
T
R
S
F
R
S
Site 58
S359
G
T
P
S
Q
T
R
S
F
R
S
A
G
L
Q
Site 59
S367
F
R
S
A
G
L
Q
S
P
N
S
P
R
C
F
Site 60
S370
A
G
L
Q
S
P
N
S
P
R
C
F
S
G
P
Site 61
S375
P
N
S
P
R
C
F
S
G
P
P
P
R
A
P
Site 62
S388
A
P
K
Q
V
T
T
S
L
K
P
R
P
C
P
Site 63
S402
P
G
P
K
R
P
V
S
L
E
L
I
L
Q
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation