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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HS1BP3
Full Name:
HCLS1-binding protein 3
Alias:
ETM2; FLJ14249; H1BP3; HCLS1 binding protein 3; HS1-binding protein 3; HS1-BP3
Type:
Mass (Da):
42780
Number AA:
392
UniProt ID:
Q53T59
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
GO:0005543
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0009987
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
Q
S
P
A
V
L
V
T
S
Site 2
T9
Q
S
P
A
V
L
V
T
S
R
R
L
Q
N
A
Site 3
S10
S
P
A
V
L
V
T
S
R
R
L
Q
N
A
H
Site 4
T23
A
H
T
G
L
D
L
T
V
P
Q
H
Q
E
V
Site 5
S54
T
R
L
A
A
F
K
S
A
K
H
R
P
E
D
Site 6
S68
D
V
V
Q
F
L
V
S
K
K
Y
S
E
I
E
Site 7
Y71
Q
F
L
V
S
K
K
Y
S
E
I
E
E
F
Y
Site 8
S72
F
L
V
S
K
K
Y
S
E
I
E
E
F
Y
Q
Site 9
Y78
Y
S
E
I
E
E
F
Y
Q
K
L
S
S
R
Y
Site 10
S82
E
E
F
Y
Q
K
L
S
S
R
Y
A
A
A
S
Site 11
S83
E
F
Y
Q
K
L
S
S
R
Y
A
A
A
S
L
Site 12
Y85
Y
Q
K
L
S
S
R
Y
A
A
A
S
L
P
P
Site 13
S89
S
S
R
Y
A
A
A
S
L
P
P
L
P
R
K
Site 14
S103
K
V
L
F
V
G
E
S
D
I
R
E
R
R
A
Site 15
S120
N
E
I
L
R
C
V
S
K
D
A
E
L
A
G
Site 16
S128
K
D
A
E
L
A
G
S
P
E
L
L
E
F
L
Site 17
T137
E
L
L
E
F
L
G
T
R
S
P
G
A
A
G
Site 18
S139
L
E
F
L
G
T
R
S
P
G
A
A
G
L
T
Site 19
T146
S
P
G
A
A
G
L
T
S
R
D
S
S
V
L
Site 20
S147
P
G
A
A
G
L
T
S
R
D
S
S
V
L
D
Site 21
S150
A
G
L
T
S
R
D
S
S
V
L
D
G
T
D
Site 22
S151
G
L
T
S
R
D
S
S
V
L
D
G
T
D
S
Site 23
T156
D
S
S
V
L
D
G
T
D
S
Q
T
G
N
D
Site 24
S158
S
V
L
D
G
T
D
S
Q
T
G
N
D
E
E
Site 25
T160
L
D
G
T
D
S
Q
T
G
N
D
E
E
A
F
Site 26
S194
K
G
E
D
A
E
E
S
L
E
E
E
E
A
L
Site 27
S209
D
P
L
G
I
M
R
S
K
K
P
K
K
H
P
Site 28
T229
A
K
P
S
P
R
L
T
I
F
D
E
E
V
D
Site 29
S249
F
G
P
G
R
K
L
S
P
Q
D
P
S
E
D
Site 30
S254
K
L
S
P
Q
D
P
S
E
D
V
S
S
V
D
Site 31
S258
Q
D
P
S
E
D
V
S
S
V
D
P
L
K
L
Site 32
S259
D
P
S
E
D
V
S
S
V
D
P
L
K
L
F
Site 33
T293
A
C
E
S
G
G
P
T
P
S
L
S
H
R
D
Site 34
S295
E
S
G
G
P
T
P
S
L
S
H
R
D
A
S
Site 35
S297
G
G
P
T
P
S
L
S
H
R
D
A
S
K
E
Site 36
S302
S
L
S
H
R
D
A
S
K
E
L
F
R
V
E
Site 37
T383
Q
Y
I
Q
D
H
D
T
P
A
Q
A
A
P
S
Site 38
S390
T
P
A
Q
A
A
P
S
L
F
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation