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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF1B
Full Name:
TATA box-binding protein-associated factor RNA polymerase I subunit B
Alias:
RNA polymerase I-specific TBP-associated factor 63 kDa;TATA box-binding protein-associated factor 1B;Transcription initiation factor SL1/TIF-IB subunit B
Type:
Mass (Da):
68832
Number AA:
588
UniProt ID:
Q53T94
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
A
A
V
S
W
G
L
T
D
E
G
K
Y
Y
C
Site 2
Y29
G
L
T
D
E
G
K
Y
Y
C
T
S
C
H
N
Site 3
Y30
L
T
D
E
G
K
Y
Y
C
T
S
C
H
N
V
Site 4
T45
T
E
R
Y
Q
E
V
T
N
T
D
L
I
P
N
Site 5
T47
R
Y
Q
E
V
T
N
T
D
L
I
P
N
T
Q
Site 6
T53
N
T
D
L
I
P
N
T
Q
I
K
A
L
N
R
Site 7
Y82
Y
V
C
E
G
F
Q
Y
I
L
Y
Q
Q
A
E
Site 8
Y85
E
G
F
Q
Y
I
L
Y
Q
Q
A
E
A
L
K
Site 9
Y112
L
H
N
F
W
K
R
Y
L
Q
K
S
K
Q
A
Site 10
Y120
L
Q
K
S
K
Q
A
Y
C
K
N
P
V
Y
T
Site 11
Y126
A
Y
C
K
N
P
V
Y
T
T
G
R
K
P
T
Site 12
T133
Y
T
T
G
R
K
P
T
V
L
E
D
N
L
S
Site 13
S140
T
V
L
E
D
N
L
S
H
S
D
W
A
S
E
Site 14
S142
L
E
D
N
L
S
H
S
D
W
A
S
E
P
E
Site 15
S146
L
S
H
S
D
W
A
S
E
P
E
L
L
S
D
Site 16
S152
A
S
E
P
E
L
L
S
D
V
S
C
P
P
F
Site 17
S162
S
C
P
P
F
L
E
S
G
A
E
S
Q
S
D
Site 18
S166
F
L
E
S
G
A
E
S
Q
S
D
I
H
T
R
Site 19
S168
E
S
G
A
E
S
Q
S
D
I
H
T
R
K
P
Site 20
T172
E
S
Q
S
D
I
H
T
R
K
P
F
P
V
S
Site 21
S179
T
R
K
P
F
P
V
S
K
A
S
Q
S
E
T
Site 22
S182
P
F
P
V
S
K
A
S
Q
S
E
T
S
V
C
Site 23
S184
P
V
S
K
A
S
Q
S
E
T
S
V
C
S
G
Site 24
T186
S
K
A
S
Q
S
E
T
S
V
C
S
G
S
L
Site 25
S187
K
A
S
Q
S
E
T
S
V
C
S
G
S
L
D
Site 26
S192
E
T
S
V
C
S
G
S
L
D
G
V
E
Y
S
Site 27
Y198
G
S
L
D
G
V
E
Y
S
Q
R
K
E
K
G
Site 28
S199
S
L
D
G
V
E
Y
S
Q
R
K
E
K
G
I
Site 29
S232
Q
R
E
A
I
T
L
S
D
L
L
R
F
V
E
Site 30
Y245
V
E
E
D
H
I
P
Y
I
N
A
F
Q
H
F
Site 31
Y259
F
P
E
Q
M
K
L
Y
G
R
D
R
G
I
F
Site 32
Y274
G
I
E
S
W
P
D
Y
E
D
I
Y
K
K
T
Site 33
Y278
W
P
D
Y
E
D
I
Y
K
K
T
V
E
V
G
Site 34
T281
Y
E
D
I
Y
K
K
T
V
E
V
G
T
F
L
Site 35
T286
K
K
T
V
E
V
G
T
F
L
D
L
P
R
F
Site 36
T297
L
P
R
F
P
D
I
T
E
D
C
Y
L
H
P
Site 37
Y301
P
D
I
T
E
D
C
Y
L
H
P
N
I
L
C
Site 38
T351
P
I
A
K
M
A
K
T
V
K
Y
D
V
Q
A
Site 39
S379
L
D
D
S
F
E
W
S
L
S
N
L
A
E
K
Site 40
S381
D
S
F
E
W
S
L
S
N
L
A
E
K
H
N
Site 41
Y425
W
E
E
A
R
A
K
Y
L
W
K
S
E
K
P
Site 42
S429
R
A
K
Y
L
W
K
S
E
K
P
L
Y
Y
S
Site 43
Y434
W
K
S
E
K
P
L
Y
Y
S
F
V
D
K
P
Site 44
S436
S
E
K
P
L
Y
Y
S
F
V
D
K
P
V
A
Site 45
S458
V
N
L
Q
K
Q
F
S
T
L
V
E
S
T
A
Site 46
T459
N
L
Q
K
Q
F
S
T
L
V
E
S
T
A
T
Site 47
T466
T
L
V
E
S
T
A
T
A
G
K
K
S
P
S
Site 48
S471
T
A
T
A
G
K
K
S
P
S
S
F
Q
F
N
Site 49
S473
T
A
G
K
K
S
P
S
S
F
Q
F
N
W
T
Site 50
S474
A
G
K
K
S
P
S
S
F
Q
F
N
W
T
E
Site 51
T487
T
E
E
D
T
D
R
T
C
F
H
G
H
S
L
Site 52
S493
R
T
C
F
H
G
H
S
L
Q
G
V
L
K
E
Site 53
S504
V
L
K
E
K
G
Q
S
L
L
T
K
N
S
L
Site 54
T507
E
K
G
Q
S
L
L
T
K
N
S
L
Y
W
L
Site 55
S510
Q
S
L
L
T
K
N
S
L
Y
W
L
S
T
Q
Site 56
Y512
L
L
T
K
N
S
L
Y
W
L
S
T
Q
K
F
Site 57
S533
H
V
T
T
Y
E
E
S
N
Y
S
L
S
Y
Q
Site 58
Y535
T
T
Y
E
E
S
N
Y
S
L
S
Y
Q
F
I
Site 59
S536
T
Y
E
E
S
N
Y
S
L
S
Y
Q
F
I
L
Site 60
S538
E
E
S
N
Y
S
L
S
Y
Q
F
I
L
N
L
Site 61
Y573
K
K
L
F
E
K
K
Y
S
V
K
R
K
K
S
Site 62
S574
K
L
F
E
K
K
Y
S
V
K
R
K
K
S
R
Site 63
S580
Y
S
V
K
R
K
K
S
R
S
K
K
V
R
R
Site 64
S582
V
K
R
K
K
S
R
S
K
K
V
R
R
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation