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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SGOL2
Full Name:
Shugoshin-like 2
Alias:
FLJ25211; Shugoshin-like 2; Tripin
Type:
Unknown function
Mass (Da):
144739
Number AA:
1265
UniProt ID:
Q562F6
International Prot ID:
IPI00657858
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030892
GO:0005634
GO:0008278
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007059
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
E
T
G
S
L
F
T
S
G
I
K
R
H
L
K
Site 2
S26
H
L
K
D
K
R
I
S
K
T
T
K
L
N
V
Site 3
T28
K
D
K
R
I
S
K
T
T
K
L
N
V
S
L
Site 4
T29
D
K
R
I
S
K
T
T
K
L
N
V
S
L
A
Site 5
S34
K
T
T
K
L
N
V
S
L
A
S
K
I
K
T
Site 6
T41
S
L
A
S
K
I
K
T
K
I
L
N
N
S
S
Site 7
S48
T
K
I
L
N
N
S
S
I
F
K
I
S
L
K
Site 8
S53
N
S
S
I
F
K
I
S
L
K
H
N
N
R
A
Site 9
S66
R
A
L
A
Q
A
L
S
R
E
K
E
N
S
R
Site 10
S72
L
S
R
E
K
E
N
S
R
R
I
T
T
E
K
Site 11
T76
K
E
N
S
R
R
I
T
T
E
K
M
L
L
Q
Site 12
T77
E
N
S
R
R
I
T
T
E
K
M
L
L
Q
K
Site 13
T94
E
K
L
N
F
E
N
T
F
L
R
L
K
L
N
Site 14
S126
I
T
A
I
E
M
S
S
L
S
E
F
H
Q
S
Site 15
S128
A
I
E
M
S
S
L
S
E
F
H
Q
S
S
F
Site 16
S133
S
L
S
E
F
H
Q
S
S
F
L
L
S
A
S
Site 17
S134
L
S
E
F
H
Q
S
S
F
L
L
S
A
S
K
Site 18
S138
H
Q
S
S
F
L
L
S
A
S
K
K
K
R
I
Site 19
S140
S
S
F
L
L
S
A
S
K
K
K
R
I
S
K
Site 20
S146
A
S
K
K
K
R
I
S
K
Q
C
K
L
M
R
Site 21
S163
F
A
R
V
P
L
T
S
N
D
D
E
D
E
D
Site 22
S182
Q
C
D
N
N
I
K
S
K
T
L
P
D
I
P
Site 23
T184
D
N
N
I
K
S
K
T
L
P
D
I
P
S
S
Site 24
S190
K
T
L
P
D
I
P
S
S
G
S
T
T
Q
P
Site 25
S191
T
L
P
D
I
P
S
S
G
S
T
T
Q
P
L
Site 26
S193
P
D
I
P
S
S
G
S
T
T
Q
P
L
S
T
Site 27
T194
D
I
P
S
S
G
S
T
T
Q
P
L
S
T
Q
Site 28
T195
I
P
S
S
G
S
T
T
Q
P
L
S
T
Q
D
Site 29
S199
G
S
T
T
Q
P
L
S
T
Q
D
N
S
E
V
Site 30
T200
S
T
T
Q
P
L
S
T
Q
D
N
S
E
V
L
Site 31
S204
P
L
S
T
Q
D
N
S
E
V
L
F
L
K
E
Site 32
S222
N
V
Y
G
L
D
D
S
E
H
I
S
S
I
V
Site 33
S226
L
D
D
S
E
H
I
S
S
I
V
D
V
P
P
Site 34
S227
D
D
S
E
H
I
S
S
I
V
D
V
P
P
R
Site 35
S236
V
D
V
P
P
R
E
S
H
S
H
S
D
Q
S
Site 36
S238
V
P
P
R
E
S
H
S
H
S
D
Q
S
S
K
Site 37
S240
P
R
E
S
H
S
H
S
D
Q
S
S
K
T
S
Site 38
S243
S
H
S
H
S
D
Q
S
S
K
T
S
L
M
S
Site 39
S244
H
S
H
S
D
Q
S
S
K
T
S
L
M
S
E
Site 40
T246
H
S
D
Q
S
S
K
T
S
L
M
S
E
M
R
Site 41
S247
S
D
Q
S
S
K
T
S
L
M
S
E
M
R
N
Site 42
S250
S
S
K
T
S
L
M
S
E
M
R
N
A
Q
S
Site 43
S257
S
E
M
R
N
A
Q
S
I
G
R
R
W
E
K
Site 44
S266
G
R
R
W
E
K
P
S
P
S
N
V
T
E
R
Site 45
S278
T
E
R
K
K
R
G
S
S
W
E
S
N
N
L
Site 46
S279
E
R
K
K
R
G
S
S
W
E
S
N
N
L
S
Site 47
S282
K
R
G
S
S
W
E
S
N
N
L
S
A
D
T
Site 48
S286
S
W
E
S
N
N
L
S
A
D
T
P
C
A
T
Site 49
T289
S
N
N
L
S
A
D
T
P
C
A
T
V
L
D
Site 50
T293
S
A
D
T
P
C
A
T
V
L
D
K
Q
H
I
Site 51
S301
V
L
D
K
Q
H
I
S
S
P
E
L
N
C
N
Site 52
S302
L
D
K
Q
H
I
S
S
P
E
L
N
C
N
N
Site 53
S334
Q
D
L
P
G
L
S
S
E
S
A
R
E
P
N
Site 54
T359
D
D
F
Q
L
Q
K
T
V
Y
D
A
D
M
D
Site 55
Y361
F
Q
L
Q
K
T
V
Y
D
A
D
M
D
L
T
Site 56
T368
Y
D
A
D
M
D
L
T
A
S
E
V
S
K
I
Site 57
S373
D
L
T
A
S
E
V
S
K
I
V
T
V
S
T
Site 58
T377
S
E
V
S
K
I
V
T
V
S
T
G
I
K
K
Site 59
S386
S
T
G
I
K
K
K
S
N
K
K
T
N
E
H
Site 60
T390
K
K
K
S
N
K
K
T
N
E
H
G
M
K
T
Site 61
T397
T
N
E
H
G
M
K
T
F
R
K
V
K
D
S
Site 62
S404
T
F
R
K
V
K
D
S
S
S
E
K
K
R
E
Site 63
S405
F
R
K
V
K
D
S
S
S
E
K
K
R
E
R
Site 64
S406
R
K
V
K
D
S
S
S
E
K
K
R
E
R
S
Site 65
S413
S
E
K
K
R
E
R
S
K
R
Q
F
K
N
S
Site 66
S420
S
K
R
Q
F
K
N
S
S
D
V
D
I
G
E
Site 67
S421
K
R
Q
F
K
N
S
S
D
V
D
I
G
E
K
Site 68
S436
I
E
N
R
T
E
R
S
D
V
L
D
G
K
R
Site 69
T497
N
K
K
E
K
R
I
T
N
E
Q
E
E
T
Y
Site 70
T503
I
T
N
E
Q
E
E
T
Y
S
L
S
Q
S
S
Site 71
S505
N
E
Q
E
E
T
Y
S
L
S
Q
S
S
G
K
Site 72
S507
Q
E
E
T
Y
S
L
S
Q
S
S
G
K
F
H
Site 73
S509
E
T
Y
S
L
S
Q
S
S
G
K
F
H
Q
E
Site 74
S517
S
G
K
F
H
Q
E
S
K
F
D
K
G
Q
N
Site 75
S525
K
F
D
K
G
Q
N
S
L
T
C
N
K
S
K
Site 76
T527
D
K
G
Q
N
S
L
T
C
N
K
S
K
A
S
Site 77
S531
N
S
L
T
C
N
K
S
K
A
S
R
Q
T
F
Site 78
T537
K
S
K
A
S
R
Q
T
F
V
I
H
K
L
E
Site 79
T557
P
N
Q
K
D
K
V
T
I
Y
E
N
L
D
V
Site 80
Y559
Q
K
D
K
V
T
I
Y
E
N
L
D
V
T
N
Site 81
T565
I
Y
E
N
L
D
V
T
N
E
F
H
T
A
N
Site 82
S574
E
F
H
T
A
N
L
S
T
K
D
N
G
N
L
Site 83
Y584
D
N
G
N
L
C
D
Y
G
T
H
N
I
L
D
Site 84
T586
G
N
L
C
D
Y
G
T
H
N
I
L
D
L
K
Site 85
Y595
N
I
L
D
L
K
K
Y
V
T
D
I
Q
P
S
Site 86
T597
L
D
L
K
K
Y
V
T
D
I
Q
P
S
E
Q
Site 87
S602
Y
V
T
D
I
Q
P
S
E
Q
N
E
S
N
I
Site 88
T620
R
K
K
V
N
R
K
T
E
I
I
S
G
M
N
Site 89
T650
K
G
N
F
F
F
K
T
Q
E
D
K
E
P
I
Site 90
S658
Q
E
D
K
E
P
I
S
E
N
I
E
V
S
K
Site 91
S673
E
L
Q
I
P
A
L
S
T
R
D
N
E
N
Q
Site 92
Y683
D
N
E
N
Q
C
D
Y
R
T
Q
N
V
L
G
Site 93
T685
E
N
Q
C
D
Y
R
T
Q
N
V
L
G
L
Q
Site 94
Y699
Q
K
Q
I
T
N
M
Y
P
V
Q
Q
N
E
S
Site 95
T720
R
Q
K
V
N
R
K
T
E
I
I
S
E
V
N
Site 96
S734
N
H
L
D
N
D
K
S
I
E
Y
T
V
K
S
Site 97
Y737
D
N
D
K
S
I
E
Y
T
V
K
S
H
S
L
Site 98
T738
N
D
K
S
I
E
Y
T
V
K
S
H
S
L
F
Site 99
S741
S
I
E
Y
T
V
K
S
H
S
L
F
L
T
Q
Site 100
S743
E
Y
T
V
K
S
H
S
L
F
L
T
Q
K
D
Site 101
T747
K
S
H
S
L
F
L
T
Q
K
D
K
E
I
I
Site 102
S762
P
G
N
L
E
D
P
S
E
F
E
T
P
A
L
Site 103
T766
E
D
P
S
E
F
E
T
P
A
L
S
T
K
D
Site 104
S770
E
F
E
T
P
A
L
S
T
K
D
S
G
N
L
Site 105
S774
P
A
L
S
T
K
D
S
G
N
L
Y
D
S
E
Site 106
Y778
T
K
D
S
G
N
L
Y
D
S
E
I
Q
N
V
Site 107
S780
D
S
G
N
L
Y
D
S
E
I
Q
N
V
L
G
Site 108
S816
R
L
N
V
C
Q
K
S
E
I
I
P
E
T
N
Site 109
Y826
I
P
E
T
N
Q
I
Y
E
N
D
N
K
G
V
Site 110
T845
K
D
N
F
F
S
L
T
P
K
D
K
E
T
I
Site 111
T851
L
T
P
K
D
K
E
T
I
S
E
N
L
Q
V
Site 112
S853
P
K
D
K
E
T
I
S
E
N
L
Q
V
T
N
Site 113
Y878
D
N
G
N
L
C
D
Y
D
T
Q
N
I
L
E
Site 114
T880
G
N
L
C
D
Y
D
T
Q
N
I
L
E
L
K
Site 115
Y889
N
I
L
E
L
K
K
Y
V
T
D
R
K
S
A
Site 116
T891
L
E
L
K
K
Y
V
T
D
R
K
S
A
E
Q
Site 117
S895
K
Y
V
T
D
R
K
S
A
E
Q
N
E
S
K
Site 118
S901
K
S
A
E
Q
N
E
S
K
I
N
K
L
R
N
Site 119
Y924
I
S
E
M
N
Q
I
Y
E
D
N
D
K
D
A
Site 120
S936
K
D
A
H
V
Q
E
S
Y
T
K
D
L
D
F
Site 121
S948
L
D
F
K
V
N
K
S
K
Q
K
L
E
C
Q
Site 122
Y962
Q
D
I
I
N
K
H
Y
M
E
V
N
S
N
E
Site 123
S979
S
C
D
Q
I
L
D
S
Y
K
V
V
K
K
R
Site 124
Y980
C
D
Q
I
L
D
S
Y
K
V
V
K
K
R
K
Site 125
S991
K
K
R
K
K
E
S
S
C
K
A
K
N
I
L
Site 126
S1007
K
A
K
N
K
L
A
S
Q
L
T
E
S
S
Q
Site 127
T1010
N
K
L
A
S
Q
L
T
E
S
S
Q
T
S
I
Site 128
S1012
L
A
S
Q
L
T
E
S
S
Q
T
S
I
S
L
Site 129
S1013
A
S
Q
L
T
E
S
S
Q
T
S
I
S
L
E
Site 130
S1016
L
T
E
S
S
Q
T
S
I
S
L
E
S
D
L
Site 131
S1018
E
S
S
Q
T
S
I
S
L
E
S
D
L
K
H
Site 132
S1028
S
D
L
K
H
I
T
S
E
A
D
S
D
P
G
Site 133
S1032
H
I
T
S
E
A
D
S
D
P
G
N
P
V
E
Site 134
T1043
N
P
V
E
L
C
K
T
Q
K
Q
S
T
T
T
Site 135
S1077
K
K
V
N
K
M
T
S
K
S
K
K
R
K
T
Site 136
S1079
V
N
K
M
T
S
K
S
K
K
R
K
T
S
I
Site 137
T1084
S
K
S
K
K
R
K
T
S
I
D
P
S
P
E
Site 138
S1085
K
S
K
K
R
K
T
S
I
D
P
S
P
E
S
Site 139
S1089
R
K
T
S
I
D
P
S
P
E
S
H
E
V
M
Site 140
S1092
S
I
D
P
S
P
E
S
H
E
V
M
E
R
I
Site 141
S1102
V
M
E
R
I
L
D
S
V
Q
G
K
S
T
V
Site 142
S1107
L
D
S
V
Q
G
K
S
T
V
S
E
Q
A
D
Site 143
T1108
D
S
V
Q
G
K
S
T
V
S
E
Q
A
D
K
Site 144
Y1132
V
K
N
K
P
D
F
Y
T
K
A
F
R
S
L
Site 145
T1133
K
N
K
P
D
F
Y
T
K
A
F
R
S
L
S
Site 146
S1138
F
Y
T
K
A
F
R
S
L
S
E
I
H
S
P
Site 147
S1140
T
K
A
F
R
S
L
S
E
I
H
S
P
N
I
Site 148
S1144
R
S
L
S
E
I
H
S
P
N
I
Q
D
S
S
Site 149
S1150
H
S
P
N
I
Q
D
S
S
F
D
S
V
R
E
Site 150
S1151
S
P
N
I
Q
D
S
S
F
D
S
V
R
E
G
Site 151
S1154
I
Q
D
S
S
F
D
S
V
R
E
G
L
V
P
Site 152
S1163
R
E
G
L
V
P
L
S
V
S
S
G
K
N
V
Site 153
S1166
L
V
P
L
S
V
S
S
G
K
N
V
I
I
K
Site 154
S1181
E
N
F
A
L
E
C
S
P
A
F
Q
V
S
D
Site 155
S1187
C
S
P
A
F
Q
V
S
D
D
E
H
E
K
M
Site 156
T1205
K
F
K
V
N
R
R
T
Q
K
S
G
I
G
D
Site 157
S1208
V
N
R
R
T
Q
K
S
G
I
G
D
R
P
L
Site 158
S1219
D
R
P
L
Q
D
L
S
N
T
S
F
V
S
N
Site 159
T1221
P
L
Q
D
L
S
N
T
S
F
V
S
N
N
T
Site 160
S1222
L
Q
D
L
S
N
T
S
F
V
S
N
N
T
A
Site 161
S1231
V
S
N
N
T
A
E
S
E
N
K
S
E
D
L
Site 162
S1235
T
A
E
S
E
N
K
S
E
D
L
S
S
E
R
Site 163
S1239
E
N
K
S
E
D
L
S
S
E
R
T
S
R
R
Site 164
S1240
N
K
S
E
D
L
S
S
E
R
T
S
R
R
R
Site 165
T1243
E
D
L
S
S
E
R
T
S
R
R
R
R
C
T
Site 166
S1244
D
L
S
S
E
R
T
S
R
R
R
R
C
T
P
Site 167
T1250
T
S
R
R
R
R
C
T
P
F
Y
F
K
E
P
Site 168
Y1253
R
R
R
C
T
P
F
Y
F
K
E
P
S
L
R
Site 169
S1258
P
F
Y
F
K
E
P
S
L
R
D
K
M
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation