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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC157
Full Name:
Coiled-coil domain-containing protein 157
Alias:
Type:
Mass (Da):
83941
Number AA:
752
UniProt ID:
Q569K6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
G
S
Q
A
C
M
E
S
L
R
A
D
L
T
D
Site 2
S39
A
G
P
V
R
F
P
S
W
K
F
P
D
R
M
Site 3
Y59
M
V
A
L
L
E
H
Y
D
H
V
P
G
D
P
Site 4
Y94
L
L
Q
S
C
M
S
Y
L
E
N
L
G
S
E
Site 5
S100
S
Y
L
E
N
L
G
S
E
Q
M
M
P
P
A
Site 6
T119
P
C
M
S
V
G
L
T
V
R
R
F
W
D
S
Site 7
T132
D
S
L
L
R
L
G
T
L
H
Q
Q
P
L
P
Site 8
T148
K
G
A
N
Q
R
E
T
P
T
S
K
P
T
T
Site 9
S151
N
Q
R
E
T
P
T
S
K
P
T
T
K
G
E
Site 10
T155
T
P
T
S
K
P
T
T
K
G
E
P
A
R
S
Site 11
S162
T
K
G
E
P
A
R
S
P
E
Y
L
T
T
K
Site 12
Y165
E
P
A
R
S
P
E
Y
L
T
T
K
L
I
K
Site 13
T168
R
S
P
E
Y
L
T
T
K
L
I
K
P
S
S
Site 14
S175
T
K
L
I
K
P
S
S
P
V
L
G
L
P
Q
Site 15
T183
P
V
L
G
L
P
Q
T
C
Q
E
P
E
S
I
Site 16
S189
Q
T
C
Q
E
P
E
S
I
P
V
R
A
S
L
Site 17
S195
E
S
I
P
V
R
A
S
L
Q
F
P
A
T
T
Site 18
T201
A
S
L
Q
F
P
A
T
T
F
K
N
T
R
S
Site 19
T202
S
L
Q
F
P
A
T
T
F
K
N
T
R
S
V
Site 20
S208
T
T
F
K
N
T
R
S
V
H
S
Q
T
I
E
Site 21
S250
Q
S
Q
N
L
P
S
S
L
G
Q
F
Q
Q
L
Site 22
T284
A
E
Q
R
K
D
L
T
R
L
S
K
H
V
E
Site 23
S287
R
K
D
L
T
R
L
S
K
H
V
E
A
L
R
Site 24
S337
E
E
D
E
Q
C
L
S
E
W
E
H
D
K
Q
Site 25
S351
Q
Q
L
L
T
E
T
S
D
L
K
T
K
M
A
Site 26
T355
T
E
T
S
D
L
K
T
K
M
A
T
L
E
R
Site 27
S370
E
L
K
Q
Q
R
E
S
T
Q
A
V
E
A
K
Site 28
T371
L
K
Q
Q
R
E
S
T
Q
A
V
E
A
K
A
Site 29
S439
K
E
K
A
R
V
D
S
M
V
R
H
Q
E
S
Site 30
S460
A
L
L
K
Q
L
D
S
L
D
Q
E
R
E
E
Site 31
S471
E
R
E
E
L
R
G
S
L
D
E
A
E
A
Q
Site 32
S488
R
V
E
E
Q
L
Q
S
E
R
E
Q
G
Q
C
Site 33
S506
A
Q
Q
E
L
L
Q
S
L
Q
R
E
K
Q
G
Site 34
T519
Q
G
L
E
Q
A
T
T
D
L
R
L
T
I
L
Site 35
T524
A
T
T
D
L
R
L
T
I
L
E
L
E
R
E
Site 36
T552
F
P
D
L
H
R
P
T
E
T
Q
I
H
G
G
Site 37
S561
T
Q
I
H
G
G
R
S
S
S
V
E
S
Q
I
Site 38
S562
Q
I
H
G
G
R
S
S
S
V
E
S
Q
I
T
Site 39
S563
I
H
G
G
R
S
S
S
V
E
S
Q
I
T
C
Site 40
S566
G
R
S
S
S
V
E
S
Q
I
T
C
P
T
D
Site 41
T569
S
S
V
E
S
Q
I
T
C
P
T
D
S
G
N
Site 42
T578
P
T
D
S
G
N
V
T
D
H
M
E
R
Q
V
Site 43
S604
E
E
N
G
R
L
Q
S
M
L
S
K
I
R
E
Site 44
S607
G
R
L
Q
S
M
L
S
K
I
R
E
V
A
Q
Site 45
S628
I
P
Q
D
R
L
W
S
P
S
S
K
G
T
Q
Site 46
S630
Q
D
R
L
W
S
P
S
S
K
G
T
Q
G
A
Site 47
S631
D
R
L
W
S
P
S
S
K
G
T
Q
G
A
T
Site 48
T634
W
S
P
S
S
K
G
T
Q
G
A
T
P
P
V
Site 49
T638
S
K
G
T
Q
G
A
T
P
P
V
Q
A
K
S
Site 50
S645
T
P
P
V
Q
A
K
S
T
S
P
G
P
L
G
Site 51
S647
P
V
Q
A
K
S
T
S
P
G
P
L
G
R
Q
Site 52
S658
L
G
R
Q
H
L
P
S
S
R
T
G
R
T
L
Site 53
S659
G
R
Q
H
L
P
S
S
R
T
G
R
T
L
L
Site 54
T661
Q
H
L
P
S
S
R
T
G
R
T
L
L
G
Q
Site 55
T664
P
S
S
R
T
G
R
T
L
L
G
Q
P
C
T
Site 56
T671
T
L
L
G
Q
P
C
T
S
P
P
R
Q
P
C
Site 57
S672
L
L
G
Q
P
C
T
S
P
P
R
Q
P
C
T
Site 58
T679
S
P
P
R
Q
P
C
T
S
P
P
R
Q
P
C
Site 59
S680
P
P
R
Q
P
C
T
S
P
P
R
Q
P
C
T
Site 60
T695
S
P
P
R
Q
P
C
T
S
P
S
R
Q
P
C
Site 61
S696
P
P
R
Q
P
C
T
S
P
S
R
Q
P
C
S
Site 62
S698
R
Q
P
C
T
S
P
S
R
Q
P
C
S
Q
P
Site 63
S703
S
P
S
R
Q
P
C
S
Q
P
S
K
S
L
L
Site 64
S706
R
Q
P
C
S
Q
P
S
K
S
L
L
E
G
V
Site 65
S708
P
C
S
Q
P
S
K
S
L
L
E
G
V
T
H
Site 66
T718
E
G
V
T
H
L
D
T
C
T
Q
N
P
I
K
Site 67
S735
V
R
L
R
K
R
L
S
P
G
R
G
Q
A
S
Site 68
S743
P
G
R
G
Q
A
S
S
A
H
Q
P
Q
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation