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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EAPP
Full Name:
E2F-associated phosphoprotein
Alias:
C14orf11
Type:
Mass (Da):
32734
Number AA:
285
UniProt ID:
Q56P03
International Prot ID:
IPI00306299
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005634
GO:0005794
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
N
R
L
P
D
D
Y
D
P
Y
A
V
E
E
Site 2
Y11
L
P
D
D
Y
D
P
Y
A
V
E
E
P
S
D
Site 3
S17
P
Y
A
V
E
E
P
S
D
E
E
P
A
L
S
Site 4
S24
S
D
E
E
P
A
L
S
S
S
E
D
E
V
D
Site 5
S25
D
E
E
P
A
L
S
S
S
E
D
E
V
D
V
Site 6
S26
E
E
P
A
L
S
S
S
E
D
E
V
D
V
L
Site 7
T37
V
D
V
L
L
H
G
T
P
D
Q
K
R
K
L
Site 8
T50
K
L
I
R
E
C
L
T
G
E
S
E
S
S
S
Site 9
S53
R
E
C
L
T
G
E
S
E
S
S
S
E
D
E
Site 10
S55
C
L
T
G
E
S
E
S
S
S
E
D
E
F
E
Site 11
S56
L
T
G
E
S
E
S
S
S
E
D
E
F
E
K
Site 12
S57
T
G
E
S
E
S
S
S
E
D
E
F
E
K
E
Site 13
T72
M
E
A
E
L
N
S
T
M
K
T
M
E
D
K
Site 14
T75
E
L
N
S
T
M
K
T
M
E
D
K
L
S
S
Site 15
S81
K
T
M
E
D
K
L
S
S
L
G
T
G
S
S
Site 16
S82
T
M
E
D
K
L
S
S
L
G
T
G
S
S
S
Site 17
T85
D
K
L
S
S
L
G
T
G
S
S
S
G
N
G
Site 18
S87
L
S
S
L
G
T
G
S
S
S
G
N
G
K
V
Site 19
S88
S
S
L
G
T
G
S
S
S
G
N
G
K
V
A
Site 20
S89
S
L
G
T
G
S
S
S
G
N
G
K
V
A
T
Site 21
T96
S
G
N
G
K
V
A
T
A
P
T
R
Y
Y
D
Site 22
Y102
A
T
A
P
T
R
Y
Y
D
D
I
Y
F
D
S
Site 23
Y106
T
R
Y
Y
D
D
I
Y
F
D
S
D
S
E
D
Site 24
S109
Y
D
D
I
Y
F
D
S
D
S
E
D
E
D
R
Site 25
S111
D
I
Y
F
D
S
D
S
E
D
E
D
R
A
V
Site 26
T121
E
D
R
A
V
Q
V
T
K
K
K
K
K
K
Q
Site 27
Y139
P
T
N
D
E
L
L
Y
D
P
E
K
D
N
R
Site 28
Y158
V
D
A
Q
R
R
G
Y
H
G
L
G
P
Q
R
Site 29
S166
H
G
L
G
P
Q
R
S
R
Q
Q
Q
P
V
P
Site 30
S175
Q
Q
Q
P
V
P
N
S
D
A
V
L
N
C
P
Site 31
T200
Q
R
H
E
S
Y
K
T
Q
Y
R
A
M
F
V
Site 32
Y220
N
K
E
E
V
L
R
Y
K
A
S
E
N
R
K
Site 33
S223
E
V
L
R
Y
K
A
S
E
N
R
K
K
R
R
Site 34
T248
D
A
A
E
K
A
E
T
D
V
E
E
I
Y
H
Site 35
Y254
E
T
D
V
E
E
I
Y
H
P
V
M
C
T
E
Site 36
Y269
C
S
T
E
V
A
V
Y
D
K
D
E
V
F
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation