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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSP90AB2P
Full Name:
Putative heat shock protein HSP 90-beta 2
Alias:
Heat shock protein 90B; Heat shock protein 90-beta b; Heat shock protein 90kDa alpha (cytosolic), class B member 2 (pseudogene); HSP90BB
Type:
Chaperone protein
Mass (Da):
44349
Number AA:
381
UniProt ID:
Q58FF8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0006950
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
L
G
E
K
E
V
E
T
F
A
F
Q
A
E
I
Site 2
Y33
S
L
I
I
N
T
F
Y
S
N
K
E
I
F
L
Site 3
Y56
D
A
L
D
K
I
R
Y
E
S
L
T
D
P
S
Site 4
S58
L
D
K
I
R
Y
E
S
L
T
D
P
S
K
L
Site 5
T60
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Site 6
S63
Y
E
S
L
T
D
P
S
K
L
D
S
G
K
E
Site 7
S67
T
D
P
S
K
L
D
S
G
K
E
L
K
I
D
Site 8
T79
K
I
D
I
I
P
N
T
Q
E
H
T
L
T
L
Site 9
T85
N
T
Q
E
H
T
L
T
L
V
D
T
G
I
G
Site 10
T89
H
T
L
T
L
V
D
T
G
I
G
M
T
K
A
Site 11
T94
V
D
T
G
I
G
M
T
K
A
D
L
I
N
N
Site 12
T104
D
L
I
N
N
L
G
T
I
A
K
F
Q
D
Q
Site 13
T112
I
A
K
F
Q
D
Q
T
E
Y
L
E
E
M
Q
Site 14
Y114
K
F
Q
D
Q
T
E
Y
L
E
E
M
Q
V
K
Site 15
Y133
K
H
S
Q
F
L
G
Y
P
I
T
L
Y
L
E
Site 16
T136
Q
F
L
G
Y
P
I
T
L
Y
L
E
K
E
R
Site 17
Y138
L
G
Y
P
I
T
L
Y
L
E
K
E
R
E
K
Site 18
S148
K
E
R
E
K
E
I
S
D
G
K
A
E
E
E
Site 19
S177
P
K
I
E
D
V
G
S
D
E
E
D
D
S
G
Site 20
S183
G
S
D
E
E
D
D
S
G
K
D
K
K
K
K
Site 21
T191
G
K
D
K
K
K
K
T
K
K
I
K
E
K
Y
Site 22
Y198
T
K
K
I
K
E
K
Y
I
D
Q
E
E
L
N
Site 23
T207
D
Q
E
E
L
N
K
T
K
P
I
W
T
R
N
Site 24
T215
K
P
I
W
T
R
N
T
E
D
I
T
Q
E
E
Site 25
T219
T
R
N
T
E
D
I
T
Q
E
E
Y
G
E
F
Site 26
Y242
K
D
H
L
A
V
R
Y
F
S
V
E
E
Y
V
Site 27
S244
H
L
A
V
R
Y
F
S
V
E
E
Y
V
S
R
Site 28
Y248
R
Y
F
S
V
E
E
Y
V
S
R
M
K
E
I
Site 29
S250
F
S
V
E
E
Y
V
S
R
M
K
E
I
Q
K
Site 30
Y260
K
E
I
Q
K
S
I
Y
Y
I
T
G
E
S
K
Site 31
Y261
E
I
Q
K
S
I
Y
Y
I
T
G
E
S
K
E
Site 32
S273
S
K
E
Q
V
A
N
S
A
F
V
E
Q
V
W
Site 33
Y288
K
R
D
S
R
V
V
Y
M
T
E
P
I
D
G
Site 34
T290
D
S
R
V
V
Y
M
T
E
P
I
D
G
Y
Q
Site 35
Y296
M
T
E
P
I
D
G
Y
Q
L
K
E
F
D
G
Site 36
S305
L
K
E
F
D
G
K
S
L
V
S
V
T
K
E
Site 37
S308
F
D
G
K
S
L
V
S
V
T
K
E
G
L
E
Site 38
T352
D
K
K
V
E
M
V
T
V
S
N
R
L
V
S
Site 39
S354
K
V
E
M
V
T
V
S
N
R
L
V
S
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation