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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RPIP8
Full Name:
RUN domain-containing protein 3A
Alias:
RaP2 interacting 8; Rap2-interacting protein 8; RAP2IP; RUN domain containing 3A
Type:
Mass (Da):
49729
Number AA:
446
UniProt ID:
Q59EK9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005083
PhosphoSite+
KinaseNET
Biological Process:
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
T
T
M
A
L
G
L
S
S
K
K
A
S
S
R
Site 2
S16
T
M
A
L
G
L
S
S
K
K
A
S
S
R
N
Site 3
S20
G
L
S
S
K
K
A
S
S
R
N
V
A
V
E
Site 4
T33
V
E
R
K
N
L
I
T
V
C
R
F
S
V
K
Site 5
T47
K
T
L
L
E
K
Y
T
A
E
P
I
D
D
S
Site 6
S54
T
A
E
P
I
D
D
S
S
E
E
F
V
N
F
Site 7
S55
A
E
P
I
D
D
S
S
E
E
F
V
N
F
A
Site 8
S83
C
A
P
A
G
P
V
S
W
F
S
S
D
G
Q
Site 9
S86
A
G
P
V
S
W
F
S
S
D
G
Q
R
G
F
Site 10
S87
G
P
V
S
W
F
S
S
D
G
Q
R
G
F
W
Site 11
Y96
G
Q
R
G
F
W
D
Y
I
R
L
A
C
S
K
Site 12
T120
E
N
M
E
N
I
S
T
A
R
A
K
G
R
A
Site 13
S139
A
L
M
E
K
R
M
S
E
Y
I
T
T
A
L
Site 14
T143
K
R
M
S
E
Y
I
T
T
A
L
R
D
T
R
Site 15
T144
R
M
S
E
Y
I
T
T
A
L
R
D
T
R
T
Site 16
T149
I
T
T
A
L
R
D
T
R
T
T
R
R
F
Y
Site 17
T151
T
A
L
R
D
T
R
T
T
R
R
F
Y
D
S
Site 18
T152
A
L
R
D
T
R
T
T
R
R
F
Y
D
S
G
Site 19
Y156
T
R
T
T
R
R
F
Y
D
S
G
A
I
M
L
Site 20
S158
T
T
R
R
F
Y
D
S
G
A
I
M
L
R
D
Site 21
Y201
K
T
P
V
V
I
D
Y
T
P
Y
L
K
F
T
Site 22
Y204
V
V
I
D
Y
T
P
Y
L
K
F
T
Q
S
Y
Site 23
S210
P
Y
L
K
F
T
Q
S
Y
D
Y
L
T
D
E
Site 24
Y211
Y
L
K
F
T
Q
S
Y
D
Y
L
T
D
E
E
Site 25
Y213
K
F
T
Q
S
Y
D
Y
L
T
D
E
E
E
R
Site 26
T215
T
Q
S
Y
D
Y
L
T
D
E
E
E
R
H
S
Site 27
S222
T
D
E
E
E
R
H
S
A
E
S
S
T
S
E
Site 28
S225
E
E
R
H
S
A
E
S
S
T
S
E
D
N
S
Site 29
S226
E
R
H
S
A
E
S
S
T
S
E
D
N
S
P
Site 30
S228
H
S
A
E
S
S
T
S
E
D
N
S
P
E
H
Site 31
S232
S
S
T
S
E
D
N
S
P
E
H
P
Y
L
P
Site 32
T242
H
P
Y
L
P
L
V
T
D
E
D
S
W
Y
S
Site 33
Y248
V
T
D
E
D
S
W
Y
S
K
W
H
K
M
E
Site 34
Y262
E
Q
K
F
R
I
V
Y
A
Q
K
G
Y
L
E
Site 35
S277
E
L
V
R
L
R
E
S
Q
L
K
D
L
E
A
Site 36
S324
Q
L
T
G
L
I
P
S
D
H
A
P
L
A
Q
Site 37
T337
A
Q
G
S
K
E
L
T
T
P
L
V
N
Q
W
Site 38
T338
Q
G
S
K
E
L
T
T
P
L
V
N
Q
W
P
Site 39
S359
G
A
E
G
A
S
N
S
K
L
Y
R
R
H
S
Site 40
Y362
G
A
S
N
S
K
L
Y
R
R
H
S
F
M
S
Site 41
S366
S
K
L
Y
R
R
H
S
F
M
S
T
E
P
L
Site 42
S369
Y
R
R
H
S
F
M
S
T
E
P
L
S
A
E
Site 43
T370
R
R
H
S
F
M
S
T
E
P
L
S
A
E
A
Site 44
S374
F
M
S
T
E
P
L
S
A
E
A
S
L
S
S
Site 45
S378
E
P
L
S
A
E
A
S
L
S
S
D
S
Q
R
Site 46
S380
L
S
A
E
A
S
L
S
S
D
S
Q
R
L
G
Site 47
S381
S
A
E
A
S
L
S
S
D
S
Q
R
L
G
E
Site 48
S383
E
A
S
L
S
S
D
S
Q
R
L
G
E
G
T
Site 49
T390
S
Q
R
L
G
E
G
T
R
D
E
E
P
W
G
Site 50
S416
G
L
C
G
S
L
A
S
I
P
S
C
K
S
L
Site 51
S419
G
S
L
A
S
I
P
S
C
K
S
L
A
S
F
Site 52
S422
A
S
I
P
S
C
K
S
L
A
S
F
K
S
N
Site 53
S425
P
S
C
K
S
L
A
S
F
K
S
N
E
C
L
Site 54
S428
K
S
L
A
S
F
K
S
N
E
C
L
V
S
D
Site 55
S434
K
S
N
E
C
L
V
S
D
S
P
E
G
S
P
Site 56
S436
N
E
C
L
V
S
D
S
P
E
G
S
P
A
L
Site 57
S440
V
S
D
S
P
E
G
S
P
A
L
S
P
S
_
Site 58
S444
P
E
G
S
P
A
L
S
P
S
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation