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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC45A4
Full Name:
Solute carrier family 45 member 4
Alias:
Type:
Mass (Da):
83878
Number AA:
768
UniProt ID:
Q5BKX6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
P
Q
N
A
D
P
E
S
M
Q
V
Q
E
L
S
Site 2
S19
S
M
Q
V
Q
E
L
S
V
P
L
P
D
P
Q
Site 3
T38
A
E
A
E
N
C
E
T
I
S
E
G
S
I
D
Site 4
S40
A
E
N
C
E
T
I
S
E
G
S
I
D
R
I
Site 5
S43
C
E
T
I
S
E
G
S
I
D
R
I
P
M
R
Site 6
Y86
Q
I
G
L
P
E
Q
Y
Y
S
L
T
W
F
L
Site 7
S88
G
L
P
E
Q
Y
Y
S
L
T
W
F
L
S
P
Site 8
S109
T
P
L
I
G
S
A
S
D
R
C
T
L
S
W
Site 9
T113
G
S
A
S
D
R
C
T
L
S
W
G
R
R
R
Site 10
S115
A
S
D
R
C
T
L
S
W
G
R
R
R
P
F
Site 11
T175
L
D
F
S
A
D
A
T
E
G
P
I
R
A
Y
Site 12
S189
Y
L
L
D
V
V
D
S
E
E
Q
D
M
A
L
Site 13
S252
S
V
A
L
H
L
F
S
I
D
E
E
Q
Y
S
Site 14
S259
S
I
D
E
E
Q
Y
S
P
Q
Q
E
R
S
A
Site 15
S265
Y
S
P
Q
Q
E
R
S
A
E
E
P
G
A
L
Site 16
Y297
E
H
E
L
A
L
D
Y
P
D
V
D
I
M
R
Site 17
S305
P
D
V
D
I
M
R
S
K
S
D
S
A
L
H
Site 18
S307
V
D
I
M
R
S
K
S
D
S
A
L
H
V
P
Site 19
S309
I
M
R
S
K
S
D
S
A
L
H
V
P
D
T
Site 20
T316
S
A
L
H
V
P
D
T
A
L
D
L
E
P
E
Site 21
S339
P
S
I
F
H
D
A
S
Y
P
A
T
P
R
S
Site 22
Y340
S
I
F
H
D
A
S
Y
P
A
T
P
R
S
T
Site 23
T343
H
D
A
S
Y
P
A
T
P
R
S
T
S
Q
E
Site 24
S346
S
Y
P
A
T
P
R
S
T
S
Q
E
L
A
K
Site 25
T347
Y
P
A
T
P
R
S
T
S
Q
E
L
A
K
T
Site 26
S348
P
A
T
P
R
S
T
S
Q
E
L
A
K
T
K
Site 27
T354
T
S
Q
E
L
A
K
T
K
L
P
R
L
A
T
Site 28
T361
T
K
L
P
R
L
A
T
F
L
K
E
A
A
K
Site 29
T372
E
A
A
K
E
D
E
T
L
L
D
N
H
L
N
Site 30
S389
K
V
P
N
G
S
G
S
P
T
K
D
A
L
G
Site 31
T391
P
N
G
S
G
S
P
T
K
D
A
L
G
G
Y
Site 32
Y398
T
K
D
A
L
G
G
Y
T
R
V
D
T
K
P
Site 33
T399
K
D
A
L
G
G
Y
T
R
V
D
T
K
P
S
Site 34
T403
G
G
Y
T
R
V
D
T
K
P
S
A
T
S
S
Site 35
S406
T
R
V
D
T
K
P
S
A
T
S
S
S
M
R
Site 36
S410
T
K
P
S
A
T
S
S
S
M
R
R
R
R
H
Site 37
S411
K
P
S
A
T
S
S
S
M
R
R
R
R
H
A
Site 38
S424
H
A
F
R
R
Q
A
S
S
T
F
S
Y
Y
G
Site 39
S425
A
F
R
R
Q
A
S
S
T
F
S
Y
Y
G
K
Site 40
T426
F
R
R
Q
A
S
S
T
F
S
Y
Y
G
K
L
Site 41
S428
R
Q
A
S
S
T
F
S
Y
Y
G
K
L
G
S
Site 42
Y429
Q
A
S
S
T
F
S
Y
Y
G
K
L
G
S
H
Site 43
Y430
A
S
S
T
F
S
Y
Y
G
K
L
G
S
H
C
Site 44
Y438
G
K
L
G
S
H
C
Y
R
Y
R
R
A
N
A
Site 45
Y440
L
G
S
H
C
Y
R
Y
R
R
A
N
A
V
V
Site 46
S454
V
L
I
K
P
S
R
S
M
S
D
L
Y
D
M
Site 47
S456
I
K
P
S
R
S
M
S
D
L
Y
D
M
Q
K
Site 48
Y459
S
R
S
M
S
D
L
Y
D
M
Q
K
R
Q
R
Site 49
S474
Q
H
R
H
R
N
Q
S
G
A
T
T
S
S
G
Site 50
T478
R
N
Q
S
G
A
T
T
S
S
G
D
T
E
S
Site 51
S479
N
Q
S
G
A
T
T
S
S
G
D
T
E
S
E
Site 52
S480
Q
S
G
A
T
T
S
S
G
D
T
E
S
E
E
Site 53
T483
A
T
T
S
S
G
D
T
E
S
E
E
G
E
G
Site 54
S485
T
S
S
G
D
T
E
S
E
E
G
E
G
E
T
Site 55
T493
E
E
G
E
G
E
T
T
V
R
L
L
W
L
S
Site 56
S546
E
G
D
P
K
A
P
S
N
S
T
A
W
Q
A
Site 57
Y582
C
S
A
L
L
Q
K
Y
L
D
N
Y
D
L
S
Site 58
Y586
L
Q
K
Y
L
D
N
Y
D
L
S
V
R
V
I
Site 59
Y642
P
Y
A
L
L
G
Q
Y
H
D
I
K
Q
Y
I
Site 60
Y648
Q
Y
H
D
I
K
Q
Y
I
H
H
S
P
G
N
Site 61
S652
I
K
Q
Y
I
H
H
S
P
G
N
S
K
R
G
Site 62
S656
I
H
H
S
P
G
N
S
K
R
G
F
G
I
D
Site 63
S720
L
V
I
Y
P
N
V
S
E
E
A
K
E
E
Q
Site 64
S731
K
E
E
Q
K
G
L
S
S
P
L
A
G
E
G
Site 65
S732
E
E
Q
K
G
L
S
S
P
L
A
G
E
G
R
Site 66
S744
E
G
R
A
G
G
N
S
E
K
P
T
V
L
K
Site 67
T748
G
G
N
S
E
K
P
T
V
L
K
L
T
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation