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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRRT3
Full Name:
Proline-rich transmembrane protein 3
Alias:
FLJ33674; proline-rich transmembrane protein 3
Type:
Mass (Da):
102179
Number AA:
981
UniProt ID:
Q5FWE3
International Prot ID:
IPI00552905
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
F
P
R
P
L
E
N
S
E
I
P
M
I
P
G
Site 2
S50
P
G
A
H
P
K
G
S
V
G
S
E
P
Q
A
Site 3
S69
P
E
N
P
R
A
D
S
H
R
N
S
D
V
R
Site 4
S73
R
A
D
S
H
R
N
S
D
V
R
H
A
P
A
Site 5
S90
M
P
E
K
P
V
A
S
P
L
G
P
A
L
Y
Site 6
Y97
S
P
L
G
P
A
L
Y
G
P
K
A
A
Q
G
Site 7
S124
Q
M
A
Q
G
P
S
S
H
G
W
T
G
P
L
Site 8
T128
G
P
S
S
H
G
W
T
G
P
L
D
S
Q
E
Site 9
S133
G
W
T
G
P
L
D
S
Q
E
L
L
Q
Q
E
Site 10
T153
P
V
G
H
P
H
L
T
F
I
P
T
T
P
R
Site 11
T157
P
H
L
T
F
I
P
T
T
P
R
R
Q
L
R
Site 12
T158
H
L
T
F
I
P
T
T
P
R
R
Q
L
R
V
Site 13
T167
R
R
Q
L
R
V
A
T
V
P
P
S
L
Q
H
Site 14
S171
R
V
A
T
V
P
P
S
L
Q
H
E
G
Q
E
Site 15
T192
D
E
G
L
K
A
K
T
K
S
R
V
P
P
T
Site 16
S194
G
L
K
A
K
T
K
S
R
V
P
P
T
S
P
Site 17
S200
K
S
R
V
P
P
T
S
P
S
D
H
Q
G
P
Site 18
S202
R
V
P
P
T
S
P
S
D
H
Q
G
P
P
H
Site 19
T210
D
H
Q
G
P
P
H
T
L
V
S
H
S
G
T
Site 20
S213
G
P
P
H
T
L
V
S
H
S
G
T
V
K
R
Site 21
T217
T
L
V
S
H
S
G
T
V
K
R
P
V
L
E
Site 22
S263
P
P
V
E
V
V
Y
S
Q
E
P
G
A
Q
P
Site 23
S277
P
D
L
A
L
A
R
S
L
P
P
A
E
E
L
Site 24
T288
A
E
E
L
P
V
E
T
P
K
R
A
G
A
E
Site 25
S297
K
R
A
G
A
E
V
S
W
E
V
S
S
P
G
Site 26
S301
A
E
V
S
W
E
V
S
S
P
G
P
P
P
K
Site 27
S302
E
V
S
W
E
V
S
S
P
G
P
P
P
K
Q
Site 28
S318
D
L
P
D
A
K
D
S
P
G
P
Q
P
T
D
Site 29
T324
D
S
P
G
P
Q
P
T
D
P
P
A
S
E
A
Site 30
S329
Q
P
T
D
P
P
A
S
E
A
P
D
R
P
S
Site 31
S336
S
E
A
P
D
R
P
S
K
P
E
R
A
A
M
Site 32
S350
M
N
G
A
D
P
I
S
P
Q
R
V
R
G
A
Site 33
T363
G
A
V
E
A
P
G
T
P
K
S
L
I
P
G
Site 34
S366
E
A
P
G
T
P
K
S
L
I
P
G
P
S
D
Site 35
S372
K
S
L
I
P
G
P
S
D
P
G
P
A
V
N
Site 36
T381
P
G
P
A
V
N
R
T
E
S
P
M
G
A
L
Site 37
S383
P
A
V
N
R
T
E
S
P
M
G
A
L
Q
P
Site 38
S402
E
W
P
G
R
P
Q
S
H
P
P
A
P
P
V
Site 39
S413
A
P
P
V
Q
A
P
S
T
S
R
R
G
L
I
Site 40
T414
P
P
V
Q
A
P
S
T
S
R
R
G
L
I
R
Site 41
S415
P
V
Q
A
P
S
T
S
R
R
G
L
I
R
V
Site 42
T423
R
R
G
L
I
R
V
T
T
Q
R
A
L
G
Q
Site 43
T424
R
G
L
I
R
V
T
T
Q
R
A
L
G
Q
P
Site 44
S439
P
P
P
E
P
T
A
S
S
M
A
S
A
P
A
Site 45
S440
P
P
E
P
T
A
S
S
M
A
S
A
P
A
S
Site 46
S443
P
T
A
S
S
M
A
S
A
P
A
S
S
P
P
Site 47
S447
S
M
A
S
A
P
A
S
S
P
P
A
N
A
T
Site 48
S448
M
A
S
A
P
A
S
S
P
P
A
N
A
T
A
Site 49
T454
S
S
P
P
A
N
A
T
A
P
P
L
R
W
G
Site 50
Y520
A
S
A
L
R
S
A
Y
M
L
T
D
P
Y
G
Site 51
Y526
A
Y
M
L
T
D
P
Y
G
S
Q
A
R
L
G
Site 52
S528
M
L
T
D
P
Y
G
S
Q
A
R
L
G
V
R
Site 53
S634
G
P
R
G
W
D
A
S
P
G
P
R
L
L
A
Site 54
T707
A
A
R
P
R
P
P
T
E
H
A
C
W
A
K
Site 55
S727
C
P
A
P
S
G
K
S
E
V
P
E
R
P
N
Site 56
Y737
P
E
R
P
N
N
C
Y
A
G
P
S
N
V
G
Site 57
S741
N
N
C
Y
A
G
P
S
N
V
G
A
G
S
L
Site 58
S747
P
S
N
V
G
A
G
S
L
D
I
S
K
S
L
Site 59
S751
G
A
G
S
L
D
I
S
K
S
L
I
R
N
P
Site 60
S753
G
S
L
D
I
S
K
S
L
I
R
N
P
A
E
Site 61
S761
L
I
R
N
P
A
E
S
G
Q
L
A
T
P
S
Site 62
T766
A
E
S
G
Q
L
A
T
P
S
S
G
A
W
G
Site 63
S768
S
G
Q
L
A
T
P
S
S
G
A
W
G
S
A
Site 64
S769
G
Q
L
A
T
P
S
S
G
A
W
G
S
A
A
Site 65
S774
P
S
S
G
A
W
G
S
A
A
S
L
G
R
G
Site 66
S777
G
A
W
G
S
A
A
S
L
G
R
G
P
Q
G
Site 67
S789
P
Q
G
G
P
G
L
S
R
N
G
V
G
P
A
Site 68
S798
N
G
V
G
P
A
P
S
L
S
E
L
D
L
R
Site 69
S800
V
G
P
A
P
S
L
S
E
L
D
L
R
P
P
Site 70
S808
E
L
D
L
R
P
P
S
P
I
N
L
S
R
S
Site 71
S813
P
P
S
P
I
N
L
S
R
S
I
D
A
A
L
Site 72
S815
S
P
I
N
L
S
R
S
I
D
A
A
L
F
R
Site 73
S829
R
E
H
L
V
R
D
S
V
F
Q
R
C
G
L
Site 74
S841
C
G
L
R
G
L
A
S
P
P
P
G
G
A
L
Site 75
S854
A
L
R
P
R
R
G
S
H
P
K
A
E
L
D
Site 76
S865
A
E
L
D
D
A
G
S
S
L
L
R
G
R
C
Site 77
S866
E
L
D
D
A
G
S
S
L
L
R
G
R
C
R
Site 78
S874
L
L
R
G
R
C
R
S
L
S
D
V
R
V
R
Site 79
S876
R
G
R
C
R
S
L
S
D
V
R
V
R
G
P
Site 80
S902
A
A
A
A
A
S
G
S
S
L
D
S
F
S
R
Site 81
S903
A
A
A
A
S
G
S
S
L
D
S
F
S
R
G
Site 82
S906
A
S
G
S
S
L
D
S
F
S
R
G
S
L
K
Site 83
S908
G
S
S
L
D
S
F
S
R
G
S
L
K
I
S
Site 84
S911
L
D
S
F
S
R
G
S
L
K
I
S
W
N
P
Site 85
S915
S
R
G
S
L
K
I
S
W
N
P
W
R
H
G
Site 86
S924
N
P
W
R
H
G
L
S
S
V
D
S
L
P
L
Site 87
S925
P
W
R
H
G
L
S
S
V
D
S
L
P
L
D
Site 88
S928
H
G
L
S
S
V
D
S
L
P
L
D
E
L
P
Site 89
S950
A
P
T
P
A
P
D
S
T
A
A
R
Q
G
D
Site 90
T951
P
T
P
A
P
D
S
T
A
A
R
Q
G
D
G
Site 91
S971
P
R
G
K
P
G
E
S
R
S
A
S
S
D
T
Site 92
S973
G
K
P
G
E
S
R
S
A
S
S
D
T
I
E
Site 93
S975
P
G
E
S
R
S
A
S
S
D
T
I
E
L
_
Site 94
S976
G
E
S
R
S
A
S
S
D
T
I
E
L
_
_
Site 95
T978
S
R
S
A
S
S
D
T
I
E
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation