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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARSI
Full Name:
Arylsulfatase I
Alias:
Arylsulfatase family, member I; ASI; EC 3.1.6.-; FLJ16069
Type:
EC 3.1.6.-; Hydrolase
Mass (Da):
64030
Number AA:
569
UniProt ID:
Q5FYB1
International Prot ID:
IPI00257076
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004065
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
L
S
F
G
Y
L
S
W
D
W
A
K
P
S
Site 2
S26
S
W
D
W
A
K
P
S
F
V
A
D
G
P
G
Site 3
S40
G
E
A
G
E
Q
P
S
A
A
P
P
Q
P
P
Site 4
T54
P
H
I
I
F
I
L
T
D
D
Q
G
Y
H
D
Site 5
Y59
I
L
T
D
D
Q
G
Y
H
D
V
G
Y
H
G
Site 6
Y64
Q
G
Y
H
D
V
G
Y
H
G
S
D
I
E
T
Site 7
S67
H
D
V
G
Y
H
G
S
D
I
E
T
P
T
L
Site 8
T71
Y
H
G
S
D
I
E
T
P
T
L
D
R
L
A
Site 9
T73
G
S
D
I
E
T
P
T
L
D
R
L
A
A
K
Site 10
Y87
K
G
V
K
L
E
N
Y
Y
I
Q
P
I
C
T
Site 11
Y88
G
V
K
L
E
N
Y
Y
I
Q
P
I
C
T
P
Site 12
T94
Y
Y
I
Q
P
I
C
T
P
S
R
S
Q
L
L
Site 13
S96
I
Q
P
I
C
T
P
S
R
S
Q
L
L
T
G
Site 14
S98
P
I
C
T
P
S
R
S
Q
L
L
T
G
R
Y
Site 15
T102
P
S
R
S
Q
L
L
T
G
R
Y
Q
I
H
T
Site 16
Y105
S
Q
L
L
T
G
R
Y
Q
I
H
T
G
L
Q
Site 17
T109
T
G
R
Y
Q
I
H
T
G
L
Q
H
S
I
I
Site 18
S114
I
H
T
G
L
Q
H
S
I
I
R
P
Q
Q
P
Site 19
T130
C
L
P
L
D
Q
V
T
L
P
Q
K
L
Q
E
Site 20
T160
Y
R
K
E
C
L
P
T
R
R
G
F
D
T
F
Site 21
T166
P
T
R
R
G
F
D
T
F
L
G
S
L
T
G
Site 22
Y177
S
L
T
G
N
V
D
Y
Y
T
Y
D
N
C
D
Site 23
Y178
L
T
G
N
V
D
Y
Y
T
Y
D
N
C
D
G
Site 24
Y180
G
N
V
D
Y
Y
T
Y
D
N
C
D
G
P
G
Site 25
S204
E
N
V
A
W
G
L
S
G
Q
Y
S
T
M
L
Site 26
Y212
G
Q
Y
S
T
M
L
Y
A
Q
R
A
S
H
I
Site 27
S217
M
L
Y
A
Q
R
A
S
H
I
L
A
S
H
S
Site 28
S222
R
A
S
H
I
L
A
S
H
S
P
Q
R
P
L
Site 29
S224
S
H
I
L
A
S
H
S
P
Q
R
P
L
F
L
Site 30
T240
V
A
F
Q
A
V
H
T
P
L
Q
S
P
R
E
Site 31
S244
A
V
H
T
P
L
Q
S
P
R
E
Y
L
Y
R
Site 32
Y248
P
L
Q
S
P
R
E
Y
L
Y
R
Y
R
T
M
Site 33
Y250
Q
S
P
R
E
Y
L
Y
R
Y
R
T
M
G
N
Site 34
Y252
P
R
E
Y
L
Y
R
Y
R
T
M
G
N
V
A
Site 35
T254
E
Y
L
Y
R
Y
R
T
M
G
N
V
A
R
R
Site 36
Y263
G
N
V
A
R
R
K
Y
A
A
M
V
T
C
M
Site 37
T278
D
E
A
V
R
N
I
T
W
A
L
K
R
Y
G
Site 38
S295
N
N
S
V
I
I
F
S
S
D
N
G
G
Q
T
Site 39
S296
N
S
V
I
I
F
S
S
D
N
G
G
Q
T
F
Site 40
T302
S
S
D
N
G
G
Q
T
F
S
G
G
S
N
W
Site 41
S304
D
N
G
G
Q
T
F
S
G
G
S
N
W
P
L
Site 42
S307
G
Q
T
F
S
G
G
S
N
W
P
L
R
G
R
Site 43
T317
P
L
R
G
R
K
G
T
Y
W
E
G
G
V
R
Site 44
Y318
L
R
G
R
K
G
T
Y
W
E
G
G
V
R
G
Site 45
S331
R
G
L
G
F
V
H
S
P
L
L
K
R
K
Q
Site 46
T340
L
L
K
R
K
Q
R
T
S
R
A
L
M
H
I
Site 47
S341
L
K
R
K
Q
R
T
S
R
A
L
M
H
I
T
Site 48
S378
Y
D
V
W
P
A
I
S
E
G
R
A
S
P
R
Site 49
S383
A
I
S
E
G
R
A
S
P
R
T
E
I
L
H
Site 50
T386
E
G
R
A
S
P
R
T
E
I
L
H
N
I
D
Site 51
Y396
L
H
N
I
D
P
L
Y
N
H
A
Q
H
G
S
Site 52
S403
Y
N
H
A
Q
H
G
S
L
E
G
G
F
G
I
Site 53
T428
V
G
E
W
K
L
L
T
G
D
P
G
Y
G
D
Site 54
Y433
L
L
T
G
D
P
G
Y
G
D
W
I
P
P
Q
Site 55
T441
G
D
W
I
P
P
Q
T
L
A
T
F
P
G
S
Site 56
T444
I
P
P
Q
T
L
A
T
F
P
G
S
W
W
N
Site 57
S468
A
V
W
L
F
N
I
S
A
D
P
Y
E
R
E
Site 58
Y472
F
N
I
S
A
D
P
Y
E
R
E
D
L
A
G
Site 59
T498
R
L
A
E
Y
N
R
T
A
I
P
V
R
Y
P
Site 60
S538
E
E
E
G
R
A
R
S
F
S
R
G
R
R
K
Site 61
S540
E
G
R
A
R
S
F
S
R
G
R
R
K
K
K
Site 62
T562
S
F
F
R
K
L
N
T
R
L
M
S
Q
R
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation