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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VWA2
Full Name:
von Willebrand factor A domain-containing protein 2
Alias:
A domain-containing protein similar to matrilin and collagen;Colon cancer secreted protein 2
Type:
Mass (Da):
82012
Number AA:
755
UniProt ID:
Q5GFL6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
F
S
R
V
P
P
S
L
P
L
Q
E
V
H
Site 2
S30
P
L
Q
E
V
H
V
S
K
E
T
I
G
K
I
Site 3
S61
F
L
L
D
G
S
N
S
V
G
K
G
S
F
E
Site 4
S66
S
N
S
V
G
K
G
S
F
E
R
S
K
H
F
Site 5
S70
G
K
G
S
F
E
R
S
K
H
F
A
I
T
V
Site 6
S84
V
C
D
G
L
D
I
S
P
E
R
V
R
V
G
Site 7
S96
R
V
G
A
F
Q
F
S
S
T
P
H
L
E
F
Site 8
T98
G
A
F
Q
F
S
S
T
P
H
L
E
F
P
L
Site 9
S107
H
L
E
F
P
L
D
S
F
S
T
Q
Q
E
V
Site 10
S109
E
F
P
L
D
S
F
S
T
Q
Q
E
V
K
A
Site 11
T130
F
K
G
G
R
T
E
T
E
L
A
L
K
Y
L
Site 12
Y136
E
T
E
L
A
L
K
Y
L
L
H
R
G
L
P
Site 13
T158
P
Q
I
L
I
I
V
T
D
G
K
S
Q
G
D
Site 14
S198
E
E
L
H
A
L
A
S
E
P
R
G
Q
H
V
Site 15
T215
A
E
Q
V
E
D
A
T
N
G
L
F
S
T
L
Site 16
S229
L
S
S
S
A
I
C
S
S
A
T
P
D
C
R
Site 17
S230
S
S
S
A
I
C
S
S
A
T
P
D
C
R
V
Site 18
T232
S
A
I
C
S
S
A
T
P
D
C
R
V
E
A
Site 19
S263
N
A
P
C
W
R
G
S
R
R
T
L
A
V
L
Site 20
T266
C
W
R
G
S
R
R
T
L
A
V
L
A
A
H
Site 21
Y291
L
T
H
P
A
T
C
Y
R
T
T
C
P
G
P
Site 22
T294
P
A
T
C
Y
R
T
T
C
P
G
P
C
D
S
Site 23
T309
Q
P
C
Q
N
G
G
T
C
V
P
E
G
L
D
Site 24
S375
R
F
V
R
A
V
L
S
E
D
S
R
A
R
V
Site 25
T420
I
P
F
R
G
G
P
T
L
T
G
S
A
L
R
Site 26
S424
G
G
P
T
L
T
G
S
A
L
R
Q
A
A
E
Site 27
S436
A
A
E
R
G
F
G
S
A
T
R
T
G
Q
D
Site 28
T440
G
F
G
S
A
T
R
T
G
Q
D
R
P
R
R
Site 29
T453
R
R
V
V
V
L
L
T
E
S
H
S
E
D
E
Site 30
S457
V
L
L
T
E
S
H
S
E
D
E
V
A
G
P
Site 31
T491
R
A
E
L
E
E
I
T
G
S
P
K
H
V
M
Site 32
S493
E
L
E
E
I
T
G
S
P
K
H
V
M
V
Y
Site 33
Y500
S
P
K
H
V
M
V
Y
S
D
P
Q
D
L
F
Site 34
S501
P
K
H
V
M
V
Y
S
D
P
Q
D
L
F
N
Site 35
S519
E
L
Q
G
K
L
C
S
R
Q
R
P
G
C
R
Site 36
T527
R
Q
R
P
G
C
R
T
Q
A
L
D
L
V
F
Site 37
S552
E
N
F
A
Q
M
Q
S
F
V
R
S
C
A
L
Site 38
T581
V
Y
G
S
Q
V
Q
T
A
F
G
L
D
T
K
Site 39
Y691
S
L
I
H
V
A
A
Y
A
D
L
R
Y
H
Q
Site 40
Y696
A
A
Y
A
D
L
R
Y
H
Q
D
V
L
I
E
Site 41
S719
P
V
N
L
C
K
P
S
P
C
M
N
E
G
S
Site 42
S726
S
P
C
M
N
E
G
S
C
V
L
Q
N
G
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation