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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
XKR4
Full Name:
XK-related protein 4
Alias:
KIAA1889; XK, Kell blood group complex subunit-related family, member 4
Type:
Mass (Da):
71500
Number AA:
UniProt ID:
Q5GH76
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
G
R
L
K
M
K
K
S
S
D
V
A
F
T
P
Site 2
S15
R
L
K
M
K
K
S
S
D
V
A
F
T
P
L
Site 3
T20
K
S
S
D
V
A
F
T
P
L
Q
N
S
D
H
Site 4
S25
A
F
T
P
L
Q
N
S
D
H
S
G
S
V
Q
Site 5
S30
Q
N
S
D
H
S
G
S
V
Q
G
L
A
P
G
Site 6
S77
G
S
G
G
S
A
G
S
G
G
S
G
G
V
A
Site 7
S93
P
G
G
G
G
A
G
S
A
A
L
C
L
R
L
Site 8
Y107
L
G
R
E
Q
R
R
Y
S
L
W
D
C
L
W
Site 9
Y136
D
V
W
L
A
V
D
Y
Y
L
R
G
Q
R
W
Site 10
S172
R
W
F
V
H
D
F
S
T
E
D
S
A
T
A
Site 11
S176
H
D
F
S
T
E
D
S
A
T
A
A
A
A
S
Site 12
T178
F
S
T
E
D
S
A
T
A
A
A
A
S
S
C
Site 13
T194
Q
P
G
A
D
C
K
T
V
V
G
G
G
S
A
Site 14
S200
K
T
V
V
G
G
G
S
A
A
G
E
G
E
A
Site 15
S210
G
E
G
E
A
R
P
S
T
P
Q
R
Q
A
S
Site 16
T211
E
G
E
A
R
P
S
T
P
Q
R
Q
A
S
N
Site 17
S217
S
T
P
Q
R
Q
A
S
N
A
S
K
S
N
I
Site 18
S220
Q
R
Q
A
S
N
A
S
K
S
N
I
A
A
A
Site 19
S222
Q
A
S
N
A
S
K
S
N
I
A
A
A
N
S
Site 20
S229
S
N
I
A
A
A
N
S
G
S
N
S
S
G
A
Site 21
S231
I
A
A
A
N
S
G
S
N
S
S
G
A
T
R
Site 22
S233
A
A
N
S
G
S
N
S
S
G
A
T
R
A
S
Site 23
T237
G
S
N
S
S
G
A
T
R
A
S
G
K
H
R
Site 24
S240
S
S
G
A
T
R
A
S
G
K
H
R
S
A
S
Site 25
S245
R
A
S
G
K
H
R
S
A
S
C
S
F
C
I
Site 26
S247
S
G
K
H
R
S
A
S
C
S
F
C
I
W
L
Site 27
Y275
W
R
Y
F
H
T
I
Y
L
G
I
R
S
R
Q
Site 28
S283
L
G
I
R
S
R
Q
S
G
E
N
D
R
W
R
Site 29
S352
S
L
A
W
A
L
A
S
Y
Q
K
A
L
R
D
Site 30
S360
Y
Q
K
A
L
R
D
S
R
D
D
K
K
P
I
Site 31
S368
R
D
D
K
K
P
I
S
Y
M
A
V
I
I
Q
Site 32
S523
N
G
P
R
F
G
Q
S
P
S
C
A
C
E
D
Site 33
S525
P
R
F
G
Q
S
P
S
C
A
C
E
D
P
A
Site 34
S544
L
P
P
D
V
A
T
S
T
L
R
S
I
S
N
Site 35
T545
P
P
D
V
A
T
S
T
L
R
S
I
S
N
N
Site 36
S548
V
A
T
S
T
L
R
S
I
S
N
N
R
S
V
Site 37
S550
T
S
T
L
R
S
I
S
N
N
R
S
V
V
S
Site 38
S554
R
S
I
S
N
N
R
S
V
V
S
D
R
D
Q
Site 39
S557
S
N
N
R
S
V
V
S
D
R
D
Q
K
F
A
Site 40
T578
P
V
F
Q
V
R
P
T
A
P
S
T
P
S
S
Site 41
S581
Q
V
R
P
T
A
P
S
T
P
S
S
R
P
P
Site 42
T582
V
R
P
T
A
P
S
T
P
S
S
R
P
P
R
Site 43
S584
P
T
A
P
S
T
P
S
S
R
P
P
R
I
E
Site 44
S585
T
A
P
S
T
P
S
S
R
P
P
R
I
E
E
Site 45
S593
R
P
P
R
I
E
E
S
V
I
K
I
D
L
F
Site 46
Y604
I
D
L
F
R
N
R
Y
P
A
W
E
R
H
V
Site 47
S615
E
R
H
V
L
D
R
S
L
R
K
A
I
L
A
Site 48
S628
L
A
F
E
C
S
P
S
P
P
R
L
Q
Y
K
Site 49
Y634
P
S
P
P
R
L
Q
Y
K
D
D
A
L
I
Q
Site 50
Y646
L
I
Q
E
R
L
E
Y
E
T
T
L
_
_
_
Site 51
T648
Q
E
R
L
E
Y
E
T
T
L
_
_
_
_
_
Site 52
T649
E
R
L
E
Y
E
T
T
L
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation