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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCAF17
Full Name:
DDB1- and CUL4-associated factor 17
Alias:
Type:
Mass (Da):
58778
Number AA:
520
UniProt ID:
Q5H9S7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
P
N
V
C
S
R
L
S
R
R
A
L
G
C
F
Site 2
T53
K
F
K
N
V
W
T
T
H
S
R
S
P
I
A
Site 3
S57
V
W
T
T
H
S
R
S
P
I
A
Y
E
R
G
Site 4
Y61
H
S
R
S
P
I
A
Y
E
R
G
R
I
Y
F
Site 5
Y67
A
Y
E
R
G
R
I
Y
F
D
N
Y
R
R
C
Site 6
Y71
G
R
I
Y
F
D
N
Y
R
R
C
V
S
S
V
Site 7
S76
D
N
Y
R
R
C
V
S
S
V
A
S
E
P
R
Site 8
S77
N
Y
R
R
C
V
S
S
V
A
S
E
P
R
K
Site 9
S80
R
C
V
S
S
V
A
S
E
P
R
K
L
Y
E
Site 10
Y86
A
S
E
P
R
K
L
Y
E
M
P
K
C
S
K
Site 11
S94
E
M
P
K
C
S
K
S
E
K
I
E
D
A
L
Site 12
S114
V
G
D
I
L
P
N
S
S
D
Y
K
S
S
L
Site 13
S115
G
D
I
L
P
N
S
S
D
Y
K
S
S
L
I
Site 14
S119
P
N
S
S
D
Y
K
S
S
L
I
A
L
T
A
Site 15
S120
N
S
S
D
Y
K
S
S
L
I
A
L
T
A
H
Site 16
Y149
E
K
I
Y
L
A
P
Y
C
K
F
R
Y
L
S
Site 17
Y154
A
P
Y
C
K
F
R
Y
L
S
W
D
T
P
Q
Site 18
T159
F
R
Y
L
S
W
D
T
P
Q
E
V
I
A
V
Site 19
S174
K
S
A
Q
N
R
G
S
A
V
A
R
Q
A
G
Site 20
T215
K
K
I
F
G
N
V
T
D
A
T
L
S
H
G
Site 21
T218
F
G
N
V
T
D
A
T
L
S
H
G
I
L
I
Site 22
Y228
H
G
I
L
I
V
M
Y
S
S
G
L
V
R
L
Site 23
S237
S
G
L
V
R
L
Y
S
F
Q
T
I
A
E
Q
Site 24
T262
A
C
R
W
G
G
T
T
G
T
V
G
E
A
P
Site 25
T264
R
W
G
G
T
T
G
T
V
G
E
A
P
F
G
Site 26
Y304
I
G
G
H
P
W
H
Y
I
V
T
P
N
K
K
Site 27
T307
H
P
W
H
Y
I
V
T
P
N
K
K
K
Q
K
Site 28
S326
I
C
A
L
K
D
N
S
L
A
K
N
G
I
Q
Site 29
Y346
S
L
E
S
D
W
I
Y
F
H
P
D
A
S
G
Site 30
S376
T
E
I
E
N
N
S
S
Q
H
Q
I
S
E
D
Site 31
T400
H
K
N
E
N
V
L
T
V
T
A
S
G
R
V
Site 32
S411
S
G
R
V
V
K
K
S
F
N
L
L
D
D
D
Site 33
Y429
E
T
F
K
I
V
D
Y
E
D
E
L
D
L
L
Site 34
S471
K
S
I
P
L
V
E
S
W
D
V
T
Y
S
H
Site 35
Y476
V
E
S
W
D
V
T
Y
S
H
E
V
Y
F
D
Site 36
Y481
V
T
Y
S
H
E
V
Y
F
D
R
D
L
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation