KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FSCB
Full Name:
Fibrous sheath CABYR-binding protein
Alias:
Type:
Mass (Da):
89188
Number AA:
837
UniProt ID:
Q5H9T9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
K
H
M
A
I
P
K
S
S
S
P
K
A
T
H
Site 2
S24
M
A
I
P
K
S
S
S
P
K
A
T
H
R
I
Site 3
T28
K
S
S
S
P
K
A
T
H
R
I
G
N
T
S
Site 4
S35
T
H
R
I
G
N
T
S
G
S
K
G
S
Y
S
Site 5
S37
R
I
G
N
T
S
G
S
K
G
S
Y
S
A
K
Site 6
S42
S
G
S
K
G
S
Y
S
A
K
A
Y
E
S
I
Site 7
Y46
G
S
Y
S
A
K
A
Y
E
S
I
R
V
S
S
Site 8
S48
Y
S
A
K
A
Y
E
S
I
R
V
S
S
E
L
Site 9
S52
A
Y
E
S
I
R
V
S
S
E
L
Q
Q
T
W
Site 10
S53
Y
E
S
I
R
V
S
S
E
L
Q
Q
T
W
T
Site 11
T58
V
S
S
E
L
Q
Q
T
W
T
K
R
K
H
G
Site 12
T60
S
E
L
Q
Q
T
W
T
K
R
K
H
G
Q
E
Site 13
S72
G
Q
E
M
T
S
K
S
L
Q
T
D
T
I
V
Site 14
T77
S
K
S
L
Q
T
D
T
I
V
E
E
K
K
E
Site 15
T91
E
V
K
L
V
E
E
T
V
V
P
E
E
K
S
Site 16
S123
E
I
P
P
N
I
P
S
V
Q
L
K
M
D
R
Site 17
S131
V
Q
L
K
M
D
R
S
Q
Q
T
S
R
T
G
Site 18
Y158
V
D
K
E
Q
Q
T
Y
F
S
E
S
E
I
V
Site 19
S162
Q
Q
T
Y
F
S
E
S
E
I
V
V
I
S
R
Site 20
S168
E
S
E
I
V
V
I
S
R
P
D
S
S
S
T
Site 21
S172
V
V
I
S
R
P
D
S
S
S
T
K
S
K
E
Site 22
S173
V
I
S
R
P
D
S
S
S
T
K
S
K
E
D
Site 23
S174
I
S
R
P
D
S
S
S
T
K
S
K
E
D
A
Site 24
S177
P
D
S
S
S
T
K
S
K
E
D
A
L
K
H
Site 25
S186
E
D
A
L
K
H
K
S
S
G
K
I
F
A
S
Site 26
S187
D
A
L
K
H
K
S
S
G
K
I
F
A
S
E
Site 27
S193
S
S
G
K
I
F
A
S
E
H
P
E
F
Q
P
Site 28
T202
H
P
E
F
Q
P
A
T
N
S
N
E
E
I
G
Site 29
S204
E
F
Q
P
A
T
N
S
N
E
E
I
G
Q
K
Site 30
S214
E
I
G
Q
K
N
I
S
R
T
S
F
T
Q
E
Site 31
S217
Q
K
N
I
S
R
T
S
F
T
Q
E
T
K
K
Site 32
T239
D
E
L
R
E
E
V
T
V
P
V
V
Q
E
G
Site 33
S261
S
A
E
I
E
P
P
S
T
E
K
F
P
A
K
Site 34
T262
A
E
I
E
P
P
S
T
E
K
F
P
A
K
I
Site 35
T289
E
P
R
P
A
E
E
T
H
V
Q
V
Q
P
S
Site 36
S296
T
H
V
Q
V
Q
P
S
T
E
E
T
P
D
A
Site 37
T300
V
Q
P
S
T
E
E
T
P
D
A
E
A
A
T
Site 38
S313
A
T
A
V
A
E
N
S
V
K
V
Q
P
P
P
Site 39
S337
P
A
E
I
Q
P
P
S
A
E
E
S
P
S
V
Site 40
S341
Q
P
P
S
A
E
E
S
P
S
V
E
L
L
A
Site 41
S343
P
S
A
E
E
S
P
S
V
E
L
L
A
E
I
Site 42
S354
L
A
E
I
L
P
P
S
A
E
E
S
P
S
E
Site 43
S358
L
P
P
S
A
E
E
S
P
S
E
E
P
P
A
Site 44
S360
P
S
A
E
E
S
P
S
E
E
P
P
A
E
I
Site 45
S375
L
P
P
P
A
E
K
S
P
S
V
E
L
L
G
Site 46
S377
P
P
A
E
K
S
P
S
V
E
L
L
G
E
I
Site 47
S386
E
L
L
G
E
I
R
S
P
S
A
Q
K
A
P
Site 48
S388
L
G
E
I
R
S
P
S
A
Q
K
A
P
I
E
Site 49
T416
P
A
K
V
E
P
P
T
V
E
E
T
L
A
D
Site 50
S443
E
A
R
E
L
Q
L
S
T
A
M
E
T
P
A
Site 51
T448
Q
L
S
T
A
M
E
T
P
A
E
E
A
P
T
Site 52
T455
T
P
A
E
E
A
P
T
E
F
Q
S
P
L
P
Site 53
S459
E
A
P
T
E
F
Q
S
P
L
P
K
E
T
T
Site 54
T487
T
E
P
P
A
D
E
T
P
A
E
A
R
S
P
Site 55
S493
E
T
P
A
E
A
R
S
P
L
S
E
E
T
S
Site 56
S496
A
E
A
R
S
P
L
S
E
E
T
S
A
E
E
Site 57
S500
S
P
L
S
E
E
T
S
A
E
E
A
H
A
E
Site 58
S510
E
A
H
A
E
V
Q
S
P
L
A
E
E
T
T
Site 59
T538
I
E
A
P
A
D
E
T
P
A
E
A
Q
S
P
Site 60
S544
E
T
P
A
E
A
Q
S
P
L
S
E
E
T
S
Site 61
S547
A
E
A
Q
S
P
L
S
E
E
T
S
A
E
E
Site 62
S551
S
P
L
S
E
E
T
S
A
E
E
A
P
A
E
Site 63
S561
E
A
P
A
E
V
Q
S
P
S
A
K
G
V
S
Site 64
S563
P
A
E
V
Q
S
P
S
A
K
G
V
S
I
E
Site 65
S568
S
P
S
A
K
G
V
S
I
E
E
A
P
L
E
Site 66
S580
P
L
E
L
Q
P
P
S
G
E
E
T
T
A
E
Site 67
T584
Q
P
P
S
G
E
E
T
T
A
E
E
A
S
A
Site 68
S680
P
P
A
E
E
A
P
S
E
V
Q
P
P
P
A
Site 69
S696
E
A
P
A
E
V
Q
S
L
P
A
E
E
T
P
Site 70
T702
Q
S
L
P
A
E
E
T
P
I
E
E
T
L
A
Site 71
S713
E
T
L
A
A
V
H
S
P
P
A
D
D
V
P
Site 72
S730
E
A
S
V
D
K
H
S
P
P
A
D
L
L
L
Site 73
S747
E
F
P
I
G
E
A
S
A
E
V
S
P
P
P
Site 74
S751
G
E
A
S
A
E
V
S
P
P
P
S
E
Q
T
Site 75
S755
A
E
V
S
P
P
P
S
E
Q
T
P
E
D
E
Site 76
T758
S
P
P
P
S
E
Q
T
P
E
D
E
A
L
V
Site 77
S769
E
A
L
V
E
N
V
S
T
E
F
Q
S
P
Q
Site 78
T770
A
L
V
E
N
V
S
T
E
F
Q
S
P
Q
V
Site 79
S774
N
V
S
T
E
F
Q
S
P
Q
V
A
G
I
P
Site 80
S800
E
A
K
F
E
E
V
S
K
I
N
S
V
L
K
Site 81
S804
E
E
V
S
K
I
N
S
V
L
K
D
L
S
N
Site 82
S810
N
S
V
L
K
D
L
S
N
T
N
D
G
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation