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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FIGN
Full Name:
Fidgetin
Alias:
Type:
Uncharacterized
Mass (Da):
82146
Number AA:
759
UniProt ID:
Q5HY92
International Prot ID:
IPI00164946
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016363
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0017111
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
I
S
S
T
S
V
Y
G
L
Site 2
Y8
M
I
S
S
T
S
V
Y
G
L
K
M
Q
W
T
Site 3
T29
P
E
Q
H
F
D
I
T
S
T
T
R
S
P
A
Site 4
S30
E
Q
H
F
D
I
T
S
T
T
R
S
P
A
H
Site 5
T31
Q
H
F
D
I
T
S
T
T
R
S
P
A
H
K
Site 6
S34
D
I
T
S
T
T
R
S
P
A
H
K
V
E
A
Site 7
Y50
R
G
H
L
Q
R
T
Y
Q
Y
A
W
A
N
D
Site 8
S60
A
W
A
N
D
D
I
S
A
L
T
A
S
N
L
Site 9
S65
D
I
S
A
L
T
A
S
N
L
L
K
K
Y
A
Site 10
Y71
A
S
N
L
L
K
K
Y
A
E
K
Y
S
G
I
Site 11
S89
P
V
D
R
P
V
L
S
N
Y
S
D
T
P
S
Site 12
Y91
D
R
P
V
L
S
N
Y
S
D
T
P
S
G
L
Site 13
S92
R
P
V
L
S
N
Y
S
D
T
P
S
G
L
V
Site 14
T94
V
L
S
N
Y
S
D
T
P
S
G
L
V
N
G
Site 15
S96
S
N
Y
S
D
T
P
S
G
L
V
N
G
R
K
Site 16
S106
V
N
G
R
K
N
E
S
E
P
W
Q
P
S
L
Site 17
S112
E
S
E
P
W
Q
P
S
L
N
S
E
A
V
Y
Site 18
S115
P
W
Q
P
S
L
N
S
E
A
V
Y
P
M
N
Site 19
Y119
S
L
N
S
E
A
V
Y
P
M
N
C
V
P
D
Site 20
S156
G
S
S
P
G
V
A
S
N
L
T
E
P
S
Y
Site 21
T159
P
G
V
A
S
N
L
T
E
P
S
Y
S
S
S
Site 22
S162
A
S
N
L
T
E
P
S
Y
S
S
S
T
C
G
Site 23
Y163
S
N
L
T
E
P
S
Y
S
S
S
T
C
G
S
Site 24
S164
N
L
T
E
P
S
Y
S
S
S
T
C
G
S
H
Site 25
S166
T
E
P
S
Y
S
S
S
T
C
G
S
H
T
V
Site 26
S170
Y
S
S
S
T
C
G
S
H
T
V
P
S
L
H
Site 27
T172
S
S
T
C
G
S
H
T
V
P
S
L
H
A
G
Site 28
S175
C
G
S
H
T
V
P
S
L
H
A
G
L
P
S
Site 29
S182
S
L
H
A
G
L
P
S
Q
E
Y
A
P
G
Y
Site 30
Y185
A
G
L
P
S
Q
E
Y
A
P
G
Y
N
G
S
Site 31
Y189
S
Q
E
Y
A
P
G
Y
N
G
S
Y
L
H
S
Site 32
S192
Y
A
P
G
Y
N
G
S
Y
L
H
S
T
Y
S
Site 33
Y193
A
P
G
Y
N
G
S
Y
L
H
S
T
Y
S
S
Site 34
S196
Y
N
G
S
Y
L
H
S
T
Y
S
S
Q
P
A
Site 35
T197
N
G
S
Y
L
H
S
T
Y
S
S
Q
P
A
P
Site 36
S199
S
Y
L
H
S
T
Y
S
S
Q
P
A
P
A
L
Site 37
S200
Y
L
H
S
T
Y
S
S
Q
P
A
P
A
L
P
Site 38
S208
Q
P
A
P
A
L
P
S
P
H
P
S
P
L
H
Site 39
S212
A
L
P
S
P
H
P
S
P
L
H
S
S
G
L
Site 40
S216
P
H
P
S
P
L
H
S
S
G
L
L
Q
P
P
Site 41
S217
H
P
S
P
L
H
S
S
G
L
L
Q
P
P
P
Site 42
Y236
P
P
A
L
V
P
G
Y
N
G
T
S
N
L
S
Site 43
T239
L
V
P
G
Y
N
G
T
S
N
L
S
S
Y
S
Site 44
S240
V
P
G
Y
N
G
T
S
N
L
S
S
Y
S
Y
Site 45
S243
Y
N
G
T
S
N
L
S
S
Y
S
Y
P
S
A
Site 46
S244
N
G
T
S
N
L
S
S
Y
S
Y
P
S
A
S
Site 47
Y245
G
T
S
N
L
S
S
Y
S
Y
P
S
A
S
Y
Site 48
S246
T
S
N
L
S
S
Y
S
Y
P
S
A
S
Y
P
Site 49
Y247
S
N
L
S
S
Y
S
Y
P
S
A
S
Y
P
P
Site 50
S249
L
S
S
Y
S
Y
P
S
A
S
Y
P
P
Q
T
Site 51
S251
S
Y
S
Y
P
S
A
S
Y
P
P
Q
T
A
V
Site 52
Y252
Y
S
Y
P
S
A
S
Y
P
P
Q
T
A
V
G
Site 53
T256
S
A
S
Y
P
P
Q
T
A
V
G
S
G
Y
S
Site 54
S260
P
P
Q
T
A
V
G
S
G
Y
S
P
G
G
A
Site 55
S263
T
A
V
G
S
G
Y
S
P
G
G
A
P
P
P
Site 56
S272
G
G
A
P
P
P
P
S
A
Y
L
P
S
G
I
Site 57
Y274
A
P
P
P
P
S
A
Y
L
P
S
G
I
P
A
Site 58
S277
P
P
S
A
Y
L
P
S
G
I
P
A
P
T
P
Site 59
T288
A
P
T
P
L
P
P
T
T
V
P
G
Y
T
Y
Site 60
T289
P
T
P
L
P
P
T
T
V
P
G
Y
T
Y
Q
Site 61
Y293
P
P
T
T
V
P
G
Y
T
Y
Q
G
H
G
L
Site 62
Y295
T
T
V
P
G
Y
T
Y
Q
G
H
G
L
T
P
Site 63
S311
A
P
S
A
L
T
N
S
S
A
S
S
L
K
R
Site 64
S312
P
S
A
L
T
N
S
S
A
S
S
L
K
R
K
Site 65
S315
L
T
N
S
S
A
S
S
L
K
R
K
A
F
Y
Site 66
Y322
S
L
K
R
K
A
F
Y
M
A
G
Q
G
D
M
Site 67
S331
A
G
Q
G
D
M
D
S
S
Y
G
N
Y
S
Y
Site 68
S332
G
Q
G
D
M
D
S
S
Y
G
N
Y
S
Y
G
Site 69
Y333
Q
G
D
M
D
S
S
Y
G
N
Y
S
Y
G
Q
Site 70
S337
D
S
S
Y
G
N
Y
S
Y
G
Q
Q
R
S
T
Site 71
Y338
S
S
Y
G
N
Y
S
Y
G
Q
Q
R
S
T
Q
Site 72
S343
Y
S
Y
G
Q
Q
R
S
T
Q
S
P
M
Y
R
Site 73
T344
S
Y
G
Q
Q
R
S
T
Q
S
P
M
Y
R
M
Site 74
S346
G
Q
Q
R
S
T
Q
S
P
M
Y
R
M
P
D
Site 75
Y349
R
S
T
Q
S
P
M
Y
R
M
P
D
N
S
I
Site 76
S355
M
Y
R
M
P
D
N
S
I
S
N
T
N
R
G
Site 77
S357
R
M
P
D
N
S
I
S
N
T
N
R
G
N
G
Site 78
T359
P
D
N
S
I
S
N
T
N
R
G
N
G
F
D
Site 79
S368
R
G
N
G
F
D
R
S
A
E
T
S
S
L
A
Site 80
S372
F
D
R
S
A
E
T
S
S
L
A
F
K
P
T
Site 81
S373
D
R
S
A
E
T
S
S
L
A
F
K
P
T
K
Site 82
T379
S
S
L
A
F
K
P
T
K
Q
L
M
S
S
E
Site 83
S385
P
T
K
Q
L
M
S
S
E
Q
Q
R
K
F
S
Site 84
S392
S
E
Q
Q
R
K
F
S
S
Q
S
S
R
A
L
Site 85
S393
E
Q
Q
R
K
F
S
S
Q
S
S
R
A
L
T
Site 86
S395
Q
R
K
F
S
S
Q
S
S
R
A
L
T
P
P
Site 87
S396
R
K
F
S
S
Q
S
S
R
A
L
T
P
P
S
Site 88
T400
S
Q
S
S
R
A
L
T
P
P
S
Y
S
T
A
Site 89
S403
S
R
A
L
T
P
P
S
Y
S
T
A
K
N
S
Site 90
Y404
R
A
L
T
P
P
S
Y
S
T
A
K
N
S
L
Site 91
S405
A
L
T
P
P
S
Y
S
T
A
K
N
S
L
G
Site 92
T406
L
T
P
P
S
Y
S
T
A
K
N
S
L
G
S
Site 93
S410
S
Y
S
T
A
K
N
S
L
G
S
R
S
S
E
Site 94
S413
T
A
K
N
S
L
G
S
R
S
S
E
S
F
G
Site 95
S415
K
N
S
L
G
S
R
S
S
E
S
F
G
K
Y
Site 96
S416
N
S
L
G
S
R
S
S
E
S
F
G
K
Y
T
Site 97
S418
L
G
S
R
S
S
E
S
F
G
K
Y
T
S
P
Site 98
Y422
S
S
E
S
F
G
K
Y
T
S
P
V
M
S
E
Site 99
T423
S
E
S
F
G
K
Y
T
S
P
V
M
S
E
H
Site 100
S424
E
S
F
G
K
Y
T
S
P
V
M
S
E
H
G
Site 101
S428
K
Y
T
S
P
V
M
S
E
H
G
D
E
H
R
Site 102
S439
D
E
H
R
Q
L
L
S
H
P
M
Q
G
P
G
Site 103
T451
G
P
G
L
R
A
A
T
S
S
N
H
S
V
D
Site 104
S452
P
G
L
R
A
A
T
S
S
N
H
S
V
D
E
Site 105
S453
G
L
R
A
A
T
S
S
N
H
S
V
D
E
Q
Site 106
S456
A
A
T
S
S
N
H
S
V
D
E
Q
L
K
N
Site 107
T466
E
Q
L
K
N
T
D
T
H
L
I
D
L
V
T
Site 108
S521
G
L
T
A
L
P
R
S
I
L
L
F
G
P
R
Site 109
T530
L
L
F
G
P
R
G
T
G
K
T
L
L
G
R
Site 110
T533
G
P
R
G
T
G
K
T
L
L
G
R
C
I
A
Site 111
S593
D
I
D
M
L
L
S
S
Q
V
N
E
E
H
S
Site 112
S600
S
Q
V
N
E
E
H
S
P
V
S
R
M
R
T
Site 113
S603
N
E
E
H
S
P
V
S
R
M
R
T
E
F
L
Site 114
T607
S
P
V
S
R
M
R
T
E
F
L
M
Q
L
D
Site 115
S639
K
P
E
E
I
D
E
S
L
R
R
Y
F
M
K
Site 116
Y643
I
D
E
S
L
R
R
Y
F
M
K
R
L
L
I
Site 117
Y671
Q
L
L
S
Q
H
N
Y
C
L
N
D
K
E
F
Site 118
S689
V
Q
R
T
E
G
F
S
G
L
D
V
A
H
L
Site 119
S719
D
L
S
A
I
M
P
S
Q
L
R
P
V
T
Y
Site 120
T725
P
S
Q
L
R
P
V
T
Y
Q
D
F
E
N
A
Site 121
Y726
S
Q
L
R
P
V
T
Y
Q
D
F
E
N
A
F
Site 122
S739
A
F
C
K
I
Q
P
S
I
S
Q
K
E
L
D
Site 123
S741
C
K
I
Q
P
S
I
S
Q
K
E
L
D
M
Y
Site 124
Y748
S
Q
K
E
L
D
M
Y
V
E
W
N
K
M
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation