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Updated November 2019
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Protein Info
Short Name:
KIAA2026
Full Name:
Uncharacterized protein KIAA2026
Alias:
Type:
Mass (Da):
133726
Number AA:
1278
UniProt ID:
Q5HYC2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
A
F
Q
R
N
R
S
R
L
K
K
D
Y
D
Site 2
Y15
R
S
R
L
K
K
D
Y
D
D
F
R
R
Q
P
Site 3
T26
R
R
Q
P
D
H
D
T
F
N
R
E
L
W
T
Site 4
T34
F
N
R
E
L
W
T
T
D
E
G
E
G
D
L
Site 5
S45
E
G
D
L
G
K
D
S
P
K
G
E
I
S
K
Site 6
S51
D
S
P
K
G
E
I
S
K
S
I
D
S
T
E
Site 7
S53
P
K
G
E
I
S
K
S
I
D
S
T
E
P
L
Site 8
S56
E
I
S
K
S
I
D
S
T
E
P
L
D
I
L
Site 9
T57
I
S
K
S
I
D
S
T
E
P
L
D
I
L
E
Site 10
S70
L
E
K
D
H
F
D
S
D
D
M
K
L
S
E
Site 11
S76
D
S
D
D
M
K
L
S
E
I
D
F
P
M
A
Site 12
T100
P
S
K
D
L
P
K
T
L
L
K
T
L
K
R
Site 13
T104
L
P
K
T
L
L
K
T
L
K
R
Q
S
K
Q
Site 14
S109
L
K
T
L
K
R
Q
S
K
Q
T
D
Y
V
D
Site 15
T112
L
K
R
Q
S
K
Q
T
D
Y
V
D
D
S
T
Site 16
Y114
R
Q
S
K
Q
T
D
Y
V
D
D
S
T
K
E
Site 17
S118
Q
T
D
Y
V
D
D
S
T
K
E
L
S
P
R
Site 18
T119
T
D
Y
V
D
D
S
T
K
E
L
S
P
R
K
Site 19
S123
D
D
S
T
K
E
L
S
P
R
K
K
A
K
L
Site 20
S131
P
R
K
K
A
K
L
S
T
N
E
T
T
V
E
Site 21
T135
A
K
L
S
T
N
E
T
T
V
E
N
L
E
S
Site 22
T136
K
L
S
T
N
E
T
T
V
E
N
L
E
S
D
Site 23
S142
T
T
V
E
N
L
E
S
D
V
Q
I
D
C
F
Site 24
S150
D
V
Q
I
D
C
F
S
E
S
K
H
T
E
P
Site 25
S152
Q
I
D
C
F
S
E
S
K
H
T
E
P
S
F
Site 26
T155
C
F
S
E
S
K
H
T
E
P
S
F
P
E
S
Site 27
S158
E
S
K
H
T
E
P
S
F
P
E
S
F
A
S
Site 28
S162
T
E
P
S
F
P
E
S
F
A
S
L
D
S
V
Site 29
S172
S
L
D
S
V
P
V
S
T
L
Q
K
G
T
K
Site 30
T196
I
G
N
K
V
T
L
T
N
Q
L
P
P
S
T
Site 31
S202
L
T
N
Q
L
P
P
S
T
G
R
N
A
L
A
Site 32
T203
T
N
Q
L
P
P
S
T
G
R
N
A
L
A
V
Site 33
S216
A
V
E
K
P
V
L
S
P
P
E
A
S
P
I
Site 34
T228
S
P
I
K
P
A
L
T
C
H
T
N
T
K
G
Site 35
Y241
K
G
P
L
Q
M
V
Y
K
M
P
C
G
Q
W
Site 36
T270
Q
P
M
V
D
P
K
T
G
E
K
I
M
Q
Q
Site 37
S312
K
G
T
E
Q
H
C
S
S
F
P
Q
T
T
N
Site 38
S313
G
T
E
Q
H
C
S
S
F
P
Q
T
T
N
I
Site 39
T317
H
C
S
S
F
P
Q
T
T
N
I
N
S
S
L
Site 40
T318
C
S
S
F
P
Q
T
T
N
I
N
S
S
L
A
Site 41
T334
V
F
V
N
S
P
G
T
V
S
T
Q
L
P
N
Site 42
T337
N
S
P
G
T
V
S
T
Q
L
P
N
T
A
F
Site 43
T342
V
S
T
Q
L
P
N
T
A
F
N
K
T
I
T
Site 44
T347
P
N
T
A
F
N
K
T
I
T
P
L
S
N
I
Site 45
T349
T
A
F
N
K
T
I
T
P
L
S
N
I
S
S
Site 46
S352
N
K
T
I
T
P
L
S
N
I
S
S
A
R
P
Site 47
S356
T
P
L
S
N
I
S
S
A
R
P
Q
P
L
S
Site 48
S363
S
A
R
P
Q
P
L
S
P
V
T
S
V
S
N
Site 49
T373
T
S
V
S
N
L
L
T
P
S
V
K
T
S
Q
Site 50
S375
V
S
N
L
L
T
P
S
V
K
T
S
Q
S
E
Site 51
S379
L
T
P
S
V
K
T
S
Q
S
E
A
G
K
A
Site 52
S381
P
S
V
K
T
S
Q
S
E
A
G
K
A
K
N
Site 53
S401
T
F
S
L
P
S
A
S
P
T
I
S
S
T
G
Site 54
T403
S
L
P
S
A
S
P
T
I
S
S
T
G
Q
P
Site 55
S405
P
S
A
S
P
T
I
S
S
T
G
Q
P
L
S
Site 56
S406
S
A
S
P
T
I
S
S
T
G
Q
P
L
S
S
Site 57
T407
A
S
P
T
I
S
S
T
G
Q
P
L
S
S
T
Site 58
S412
S
S
T
G
Q
P
L
S
S
T
T
T
L
N
G
Site 59
S413
S
T
G
Q
P
L
S
S
T
T
T
L
N
G
S
Site 60
T414
T
G
Q
P
L
S
S
T
T
T
L
N
G
S
T
Site 61
T416
Q
P
L
S
S
T
T
T
L
N
G
S
T
N
P
Site 62
S420
S
T
T
T
L
N
G
S
T
N
P
G
S
S
F
Site 63
T421
T
T
T
L
N
G
S
T
N
P
G
S
S
F
N
Site 64
S425
N
G
S
T
N
P
G
S
S
F
N
C
F
A
Q
Site 65
S426
G
S
T
N
P
G
S
S
F
N
C
F
A
Q
Q
Site 66
T446
E
A
K
Q
E
L
K
T
V
C
I
R
D
S
Q
Site 67
S452
K
T
V
C
I
R
D
S
Q
S
I
L
V
R
T
Site 68
S454
V
C
I
R
D
S
Q
S
I
L
V
R
T
R
G
Site 69
S477
Q
T
N
P
D
Q
N
S
P
N
T
V
S
S
S
Site 70
T480
P
D
Q
N
S
P
N
T
V
S
S
S
S
V
F
Site 71
S482
Q
N
S
P
N
T
V
S
S
S
S
V
F
T
F
Site 72
S483
N
S
P
N
T
V
S
S
S
S
V
F
T
F
A
Site 73
S484
S
P
N
T
V
S
S
S
S
V
F
T
F
A
P
Site 74
S485
P
N
T
V
S
S
S
S
V
F
T
F
A
P
Q
Site 75
S501
Q
A
F
L
V
P
K
S
T
T
S
S
S
A
F
Site 76
S504
L
V
P
K
S
T
T
S
S
S
A
F
S
P
V
Site 77
S505
V
P
K
S
T
T
S
S
S
A
F
S
P
V
A
Site 78
S506
P
K
S
T
T
S
S
S
A
F
S
P
V
A
G
Site 79
S509
T
T
S
S
S
A
F
S
P
V
A
G
T
T
T
Site 80
T515
F
S
P
V
A
G
T
T
T
T
S
S
L
S
P
Site 81
T516
S
P
V
A
G
T
T
T
T
S
S
L
S
P
F
Site 82
T517
P
V
A
G
T
T
T
T
S
S
L
S
P
F
S
Site 83
S519
A
G
T
T
T
T
S
S
L
S
P
F
S
Q
T
Site 84
S521
T
T
T
T
S
S
L
S
P
F
S
Q
T
P
T
Site 85
S524
T
S
S
L
S
P
F
S
Q
T
P
T
S
V
S
Site 86
T526
S
L
S
P
F
S
Q
T
P
T
S
V
S
I
P
Site 87
T528
S
P
F
S
Q
T
P
T
S
V
S
I
P
A
S
Site 88
S529
P
F
S
Q
T
P
T
S
V
S
I
P
A
S
F
Site 89
S531
S
Q
T
P
T
S
V
S
I
P
A
S
F
A
P
Site 90
T547
M
G
K
N
L
K
L
T
L
G
H
T
T
G
S
Site 91
T564
L
G
H
V
I
D
K
T
S
H
M
P
S
S
P
Site 92
S565
G
H
V
I
D
K
T
S
H
M
P
S
S
P
L
Site 93
S569
D
K
T
S
H
M
P
S
S
P
L
K
S
S
I
Site 94
S570
K
T
S
H
M
P
S
S
P
L
K
S
S
I
C
Site 95
S574
M
P
S
S
P
L
K
S
S
I
C
S
S
T
L
Site 96
T580
K
S
S
I
C
S
S
T
L
L
P
S
T
T
S
Site 97
S584
C
S
S
T
L
L
P
S
T
T
S
S
S
V
S
Site 98
T610
N
N
A
N
I
I
H
T
P
T
K
Q
Q
Q
V
Site 99
Y619
T
K
Q
Q
Q
V
D
Y
I
T
K
S
Y
P
V
Site 100
S623
Q
V
D
Y
I
T
K
S
Y
P
V
T
R
S
E
Site 101
T627
I
T
K
S
Y
P
V
T
R
S
E
A
T
A
A
Site 102
S641
A
T
N
G
D
V
I
S
G
T
P
V
Q
K
L
Site 103
S659
S
A
P
S
I
L
S
S
G
N
G
T
A
I
N
Site 104
T668
N
G
T
A
I
N
M
T
P
A
L
T
S
T
G
Site 105
S673
N
M
T
P
A
L
T
S
T
G
V
S
A
Q
K
Site 106
T694
P
V
P
S
G
T
S
T
P
T
L
V
A
E
S
Site 107
T696
P
S
G
T
S
T
P
T
L
V
A
E
S
L
K
Site 108
S701
T
P
T
L
V
A
E
S
L
K
Q
T
L
P
P
Site 109
T705
V
A
E
S
L
K
Q
T
L
P
P
P
L
H
K
Site 110
Y714
P
P
P
L
H
K
A
Y
V
K
T
P
E
Q
P
Site 111
T717
L
H
K
A
Y
V
K
T
P
E
Q
P
Q
I
V
Site 112
S738
G
T
P
I
K
I
N
S
S
P
A
V
S
Q
I
Site 113
S739
T
P
I
K
I
N
S
S
P
A
V
S
Q
I
K
Site 114
S743
I
N
S
S
P
A
V
S
Q
I
K
D
V
K
I
Site 115
T778
I
N
I
L
Q
N
V
T
P
K
G
E
D
K
S
Site 116
S785
T
P
K
G
E
D
K
S
S
K
G
Y
I
L
P
Site 117
S786
P
K
G
E
D
K
S
S
K
G
Y
I
L
P
L
Site 118
Y789
E
D
K
S
S
K
G
Y
I
L
P
L
S
T
S
Site 119
S794
K
G
Y
I
L
P
L
S
T
S
G
N
S
V
P
Site 120
S799
P
L
S
T
S
G
N
S
V
P
V
S
S
N
F
Site 121
S803
S
G
N
S
V
P
V
S
S
N
F
V
S
Q
N
Site 122
S804
G
N
S
V
P
V
S
S
N
F
V
S
Q
N
I
Site 123
S808
P
V
S
S
N
F
V
S
Q
N
I
T
P
V
N
Site 124
S817
N
I
T
P
V
N
E
S
V
V
S
S
A
R
A
Site 125
S846
S
F
P
V
T
S
A
S
A
S
A
G
A
Q
P
Site 126
S858
A
Q
P
P
V
L
V
S
G
N
D
T
S
S
R
Site 127
S864
V
S
G
N
D
T
S
S
R
I
M
P
I
L
S
Site 128
S871
S
R
I
M
P
I
L
S
N
R
L
C
S
S
S
Site 129
S896
K
T
G
H
L
A
S
S
V
L
I
S
T
T
Q
Site 130
S907
S
T
T
Q
P
V
V
S
P
K
C
L
T
S
A
Site 131
S949
A
V
P
G
A
T
R
S
V
S
I
S
K
R
Q
Site 132
S951
P
G
A
T
R
S
V
S
I
S
K
R
Q
S
R
Site 133
S953
A
T
R
S
V
S
I
S
K
R
Q
S
R
T
S
Site 134
S957
V
S
I
S
K
R
Q
S
R
T
S
L
Q
F
H
Site 135
S960
S
K
R
Q
S
R
T
S
L
Q
F
H
S
P
G
Site 136
S965
R
T
S
L
Q
F
H
S
P
G
I
S
T
T
V
Site 137
S969
Q
F
H
S
P
G
I
S
T
T
V
P
T
N
V
Site 138
T971
H
S
P
G
I
S
T
T
V
P
T
N
V
N
T
Site 139
T983
V
N
T
N
K
P
Q
T
E
L
S
S
L
S
T
Site 140
S986
N
K
P
Q
T
E
L
S
S
L
S
T
S
P
G
Site 141
S987
K
P
Q
T
E
L
S
S
L
S
T
S
P
G
K
Site 142
S989
Q
T
E
L
S
S
L
S
T
S
P
G
K
I
T
Site 143
T990
T
E
L
S
S
L
S
T
S
P
G
K
I
T
N
Site 144
S991
E
L
S
S
L
S
T
S
P
G
K
I
T
N
T
Site 145
T998
S
P
G
K
I
T
N
T
S
N
F
A
S
L
P
Site 146
S999
P
G
K
I
T
N
T
S
N
F
A
S
L
P
N
Site 147
S1003
T
N
T
S
N
F
A
S
L
P
N
Q
Q
A
L
Site 148
T1013
N
Q
Q
A
L
V
K
T
P
S
Y
S
S
A
P
Site 149
S1015
Q
A
L
V
K
T
P
S
Y
S
S
A
P
G
G
Site 150
Y1016
A
L
V
K
T
P
S
Y
S
S
A
P
G
G
T
Site 151
S1017
L
V
K
T
P
S
Y
S
S
A
P
G
G
T
T
Site 152
S1018
V
K
T
P
S
Y
S
S
A
P
G
G
T
T
I
Site 153
T1027
P
G
G
T
T
I
H
T
A
S
A
P
S
N
V
Site 154
S1029
G
T
T
I
H
T
A
S
A
P
S
N
V
T
S
Site 155
S1036
S
A
P
S
N
V
T
S
L
V
G
S
Q
F
S
Site 156
S1043
S
L
V
G
S
Q
F
S
E
P
C
I
Q
Q
K
Site 157
S1089
G
S
H
V
L
L
I
S
T
N
P
K
Y
G
A
Site 158
S1108
N
S
G
Q
G
I
Q
S
T
P
I
D
N
S
A
Site 159
T1109
S
G
Q
G
I
Q
S
T
P
I
D
N
S
A
Q
Site 160
S1114
Q
S
T
P
I
D
N
S
A
Q
K
I
T
L
A
Site 161
S1122
A
Q
K
I
T
L
A
S
N
N
S
L
S
G
Q
Site 162
S1125
I
T
L
A
S
N
N
S
L
S
G
Q
P
L
Q
Site 163
S1127
L
A
S
N
N
S
L
S
G
Q
P
L
Q
H
P
Site 164
S1137
P
L
Q
H
P
L
R
S
P
T
K
F
I
N
S
Site 165
T1139
Q
H
P
L
R
S
P
T
K
F
I
N
S
F
G
Site 166
S1144
S
P
T
K
F
I
N
S
F
G
N
A
S
S
I
Site 167
S1150
N
S
F
G
N
A
S
S
I
P
T
V
H
T
S
Site 168
T1153
G
N
A
S
S
I
P
T
V
H
T
S
P
Q
L
Site 169
S1157
S
I
P
T
V
H
T
S
P
Q
L
I
N
T
T
Site 170
S1207
P
S
N
P
P
L
P
S
S
T
S
V
F
H
L
Site 171
S1208
S
N
P
P
L
P
S
S
T
S
V
F
H
L
D
Site 172
S1210
P
P
L
P
S
S
T
S
V
F
H
L
D
P
P
Site 173
S1238
N
T
I
N
T
P
A
S
K
V
S
S
L
S
P
Site 174
S1242
T
P
A
S
K
V
S
S
L
S
P
S
L
S
Q
Site 175
S1260
S
A
S
R
S
P
A
S
V
F
P
A
F
Q
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation