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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPM1J
Full Name:
Protein phosphatase 1J
Alias:
EC 3.1.3.16; PP2CZ; PP2Czeta; PPP2CZ; Protein phosphatase 2C zeta
Type:
Protein-serine phosphatase, PP2C family
Mass (Da):
54834
Number AA:
505
UniProt ID:
Q5JR12
International Prot ID:
IPI00376886
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004721
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
A
P
P
P
R
P
K
S
P
D
L
P
N
A
A
Site 2
S33
P
D
L
P
N
A
A
S
A
P
P
A
A
A
P
Site 3
S45
A
A
P
E
A
P
R
S
P
P
A
K
A
G
S
Site 4
S52
S
P
P
A
K
A
G
S
G
S
A
T
P
A
K
Site 5
S54
P
A
K
A
G
S
G
S
A
T
P
A
K
A
V
Site 6
T56
K
A
G
S
G
S
A
T
P
A
K
A
V
E
A
Site 7
S66
K
A
V
E
A
R
A
S
F
S
R
P
T
F
L
Site 8
S68
V
E
A
R
A
S
F
S
R
P
T
F
L
Q
L
Site 9
T71
R
A
S
F
S
R
P
T
F
L
Q
L
S
P
G
Site 10
S76
R
P
T
F
L
Q
L
S
P
G
G
L
R
R
A
Site 11
S93
H
A
G
R
A
V
Q
S
P
P
D
T
G
R
R
Site 12
T97
A
V
Q
S
P
P
D
T
G
R
R
L
P
W
S
Site 13
S104
T
G
R
R
L
P
W
S
T
G
Y
A
E
V
I
Site 14
T105
G
R
R
L
P
W
S
T
G
Y
A
E
V
I
N
Site 15
Y107
R
L
P
W
S
T
G
Y
A
E
V
I
N
A
G
Site 16
S116
E
V
I
N
A
G
K
S
R
H
N
E
D
Q
A
Site 17
S135
V
Y
V
E
G
R
R
S
V
T
G
V
P
R
E
Site 18
T137
V
E
G
R
R
S
V
T
G
V
P
R
E
P
S
Site 19
S144
T
G
V
P
R
E
P
S
R
G
Q
G
L
C
F
Site 20
Y152
R
G
Q
G
L
C
F
Y
Y
W
G
L
F
D
G
Site 21
S170
G
G
A
A
E
M
A
S
R
L
L
H
R
H
I
Site 22
T200
P
P
P
L
C
L
P
T
T
P
G
T
P
D
S
Site 23
T201
P
P
L
C
L
P
T
T
P
G
T
P
D
S
S
Site 24
T204
C
L
P
T
T
P
G
T
P
D
S
S
D
P
S
Site 25
S207
T
T
P
G
T
P
D
S
S
D
P
S
H
L
L
Site 26
S208
T
P
G
T
P
D
S
S
D
P
S
H
L
L
G
Site 27
S211
T
P
D
S
S
D
P
S
H
L
L
G
P
Q
S
Site 28
S218
S
H
L
L
G
P
Q
S
C
W
S
S
Q
K
E
Site 29
S221
L
G
P
Q
S
C
W
S
S
Q
K
E
V
S
H
Site 30
S222
G
P
Q
S
C
W
S
S
Q
K
E
V
S
H
E
Site 31
S227
W
S
S
Q
K
E
V
S
H
E
S
L
V
V
G
Site 32
S280
Y
V
A
N
A
G
D
S
R
A
I
I
V
R
N
Site 33
S294
N
G
E
I
I
P
M
S
R
E
F
T
P
E
T
Site 34
T298
I
P
M
S
R
E
F
T
P
E
T
E
R
Q
R
Site 35
T301
S
R
E
F
T
P
E
T
E
R
Q
R
L
Q
L
Site 36
S319
L
K
P
E
L
L
G
S
E
F
T
H
L
E
F
Site 37
Y341
E
L
G
Q
R
M
L
Y
R
D
Q
N
M
T
G
Site 38
T380
V
M
A
T
I
G
V
T
R
G
L
G
D
H
S
Site 39
S387
T
R
G
L
G
D
H
S
L
K
V
C
S
S
T
Site 40
S402
L
P
I
K
P
F
L
S
C
F
P
E
V
R
V
Site 41
Y410
C
F
P
E
V
R
V
Y
D
L
T
Q
Y
E
H
Site 42
T413
E
V
R
V
Y
D
L
T
Q
Y
E
H
C
P
D
Site 43
Y415
R
V
Y
D
L
T
Q
Y
E
H
C
P
D
D
V
Site 44
S448
A
T
V
D
R
V
L
S
A
Y
E
P
N
D
H
Site 45
Y450
V
D
R
V
L
S
A
Y
E
P
N
D
H
S
R
Site 46
Y458
E
P
N
D
H
S
R
Y
T
A
L
A
Q
A
L
Site 47
T459
P
N
D
H
S
R
Y
T
A
L
A
Q
A
L
V
Site 48
T472
L
V
L
G
A
R
G
T
P
R
D
R
G
W
R
Site 49
S487
L
P
N
N
K
L
G
S
G
D
D
I
S
V
F
Site 50
S492
L
G
S
G
D
D
I
S
V
F
V
I
P
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation