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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR44
Full Name:
WD repeat-containing protein 44
Alias:
DKFZp686L20145; MGC26781; RAB11BP; Rabphilin-11; RPH11; Similar to rab11-binding protein
Type:
Vesicle protein
Mass (Da):
101366
Number AA:
913
UniProt ID:
Q5JSH3
International Prot ID:
IPI00444371
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005829
GO:0010008
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
E
S
D
T
E
E
F
Site 2
S5
_
_
_
M
A
S
E
S
D
T
E
E
F
Y
D
Site 3
T7
_
M
A
S
E
S
D
T
E
E
F
Y
D
A
P
Site 4
Y11
E
S
D
T
E
E
F
Y
D
A
P
E
D
V
H
Site 5
Y23
D
V
H
L
G
G
G
Y
P
V
G
S
P
G
K
Site 6
S27
G
G
G
Y
P
V
G
S
P
G
K
V
G
L
S
Site 7
S34
S
P
G
K
V
G
L
S
T
F
K
E
T
E
N
Site 8
T35
P
G
K
V
G
L
S
T
F
K
E
T
E
N
T
Site 9
T42
T
F
K
E
T
E
N
T
A
Y
K
V
G
N
E
Site 10
Y44
K
E
T
E
N
T
A
Y
K
V
G
N
E
S
P
Site 11
S50
A
Y
K
V
G
N
E
S
P
V
Q
E
L
K
Q
Site 12
S60
Q
E
L
K
Q
D
V
S
K
K
I
I
E
S
I
Site 13
S66
V
S
K
K
I
I
E
S
I
I
E
E
S
Q
K
Site 14
S81
V
L
Q
L
E
D
D
S
L
D
S
K
G
K
E
Site 15
S84
L
E
D
D
S
L
D
S
K
G
K
E
L
S
D
Site 16
S90
D
S
K
G
K
E
L
S
D
Q
A
T
A
S
P
Site 17
T94
K
E
L
S
D
Q
A
T
A
S
P
I
V
A
R
Site 18
S96
L
S
D
Q
A
T
A
S
P
I
V
A
R
T
D
Site 19
S121
D
Q
V
L
P
E
E
S
Q
K
A
E
S
Q
N
Site 20
S126
E
E
S
Q
K
A
E
S
Q
N
T
F
E
E
T
Site 21
T129
Q
K
A
E
S
Q
N
T
F
E
E
T
E
L
E
Site 22
S143
E
L
K
K
C
F
P
S
D
E
T
C
E
K
P
Site 23
T158
V
D
E
T
T
K
L
T
Q
T
S
S
T
E
Q
Site 24
T160
E
T
T
K
L
T
Q
T
S
S
T
E
Q
L
N
Site 25
S161
T
T
K
L
T
Q
T
S
S
T
E
Q
L
N
V
Site 26
S162
T
K
L
T
Q
T
S
S
T
E
Q
L
N
V
L
Site 27
T163
K
L
T
Q
T
S
S
T
E
Q
L
N
V
L
E
Site 28
T173
L
N
V
L
E
T
E
T
E
V
L
N
K
E
A
Site 29
S194
G
D
V
L
E
P
V
S
S
D
S
L
S
T
K
Site 30
S195
D
V
L
E
P
V
S
S
D
S
L
S
T
K
D
Site 31
S197
L
E
P
V
S
S
D
S
L
S
T
K
D
F
A
Site 32
S199
P
V
S
S
D
S
L
S
T
K
D
F
A
A
V
Site 33
T200
V
S
S
D
S
L
S
T
K
D
F
A
A
V
E
Site 34
T219
A
K
P
P
R
H
L
T
P
E
P
D
I
V
A
Site 35
T228
E
P
D
I
V
A
S
T
K
K
P
V
P
A
R
Site 36
T240
P
A
R
P
P
P
P
T
N
F
P
P
P
R
P
Site 37
S251
P
P
R
P
P
P
P
S
R
P
A
P
P
P
R
Site 38
S262
P
P
P
R
K
R
K
S
E
L
E
F
E
T
L
Site 39
T271
L
E
F
E
T
L
K
T
P
D
I
D
V
P
K
Site 40
S283
V
P
K
E
N
I
T
S
D
S
L
L
T
A
S
Site 41
S285
K
E
N
I
T
S
D
S
L
L
T
A
S
M
A
Site 42
S295
T
A
S
M
A
S
E
S
T
V
K
D
S
Q
P
Site 43
T296
A
S
M
A
S
E
S
T
V
K
D
S
Q
P
S
Site 44
S300
S
E
S
T
V
K
D
S
Q
P
S
L
D
L
A
Site 45
S303
T
V
K
D
S
Q
P
S
L
D
L
A
S
A
T
Site 46
S308
Q
P
S
L
D
L
A
S
A
T
S
G
D
K
I
Site 47
T310
S
L
D
L
A
S
A
T
S
G
D
K
I
V
T
Site 48
T329
G
K
A
P
D
G
Q
T
V
A
G
E
V
M
G
Site 49
S342
M
G
P
Q
R
P
R
S
N
S
G
R
E
L
T
Site 50
S344
P
Q
R
P
R
S
N
S
G
R
E
L
T
D
E
Site 51
T349
S
N
S
G
R
E
L
T
D
E
E
I
L
A
S
Site 52
T364
V
M
I
K
N
L
D
T
G
E
E
I
P
L
S
Site 53
S371
T
G
E
E
I
P
L
S
L
A
E
E
K
L
P
Site 54
T385
P
T
G
I
N
P
L
T
L
H
I
M
R
R
T
Site 55
T392
T
L
H
I
M
R
R
T
K
E
Y
V
S
N
D
Site 56
Y395
I
M
R
R
T
K
E
Y
V
S
N
D
A
A
Q
Site 57
S397
R
R
T
K
E
Y
V
S
N
D
A
A
Q
S
D
Site 58
S403
V
S
N
D
A
A
Q
S
D
D
E
E
K
L
Q
Site 59
S411
D
D
E
E
K
L
Q
S
Q
P
T
D
T
D
G
Site 60
T414
E
K
L
Q
S
Q
P
T
D
T
D
G
G
R
L
Site 61
T416
L
Q
S
Q
P
T
D
T
D
G
G
R
L
K
Q
Site 62
T425
G
G
R
L
K
Q
K
T
T
Q
L
K
K
F
L
Site 63
T426
G
R
L
K
Q
K
T
T
Q
L
K
K
F
L
G
Site 64
S435
L
K
K
F
L
G
K
S
V
K
R
A
K
H
L
Site 65
Y446
A
K
H
L
A
E
E
Y
G
E
R
A
I
N
K
Site 66
S456
R
A
I
N
K
V
K
S
V
R
D
E
V
F
H
Site 67
T464
V
R
D
E
V
F
H
T
D
Q
D
D
P
S
S
Site 68
S470
H
T
D
Q
D
D
P
S
S
S
D
D
E
G
M
Site 69
S471
T
D
Q
D
D
P
S
S
S
D
D
E
G
M
P
Site 70
S472
D
Q
D
D
P
S
S
S
D
D
E
G
M
P
Y
Site 71
Y479
S
D
D
E
G
M
P
Y
T
R
P
V
K
F
K
Site 72
T480
D
D
E
G
M
P
Y
T
R
P
V
K
F
K
A
Site 73
Y495
A
H
G
F
K
G
P
Y
D
F
D
Q
I
K
V
Site 74
Y546
A
L
K
N
A
F
D
Y
F
N
N
M
R
M
K
Site 75
Y554
F
N
N
M
R
M
K
Y
N
T
E
G
R
V
S
Site 76
T556
N
M
R
M
K
Y
N
T
E
G
R
V
S
P
S
Site 77
S561
Y
N
T
E
G
R
V
S
P
S
P
S
Q
E
S
Site 78
S563
T
E
G
R
V
S
P
S
P
S
Q
E
S
L
S
Site 79
S565
G
R
V
S
P
S
P
S
Q
E
S
L
S
S
S
Site 80
S568
S
P
S
P
S
Q
E
S
L
S
S
S
K
S
D
Site 81
S570
S
P
S
Q
E
S
L
S
S
S
K
S
D
T
D
Site 82
S571
P
S
Q
E
S
L
S
S
S
K
S
D
T
D
T
Site 83
S572
S
Q
E
S
L
S
S
S
K
S
D
T
D
T
G
Site 84
S574
E
S
L
S
S
S
K
S
D
T
D
T
G
V
C
Site 85
T576
L
S
S
S
K
S
D
T
D
T
G
V
C
S
G
Site 86
T578
S
S
K
S
D
T
D
T
G
V
C
S
G
T
D
Site 87
S582
D
T
D
T
G
V
C
S
G
T
D
E
D
P
D
Site 88
Y603
R
Q
R
P
F
C
K
Y
K
G
H
T
A
D
L
Site 89
S614
T
A
D
L
L
D
L
S
W
S
K
N
Y
F
L
Site 90
S616
D
L
L
D
L
S
W
S
K
N
Y
F
L
L
S
Site 91
Y619
D
L
S
W
S
K
N
Y
F
L
L
S
S
S
M
Site 92
S623
S
K
N
Y
F
L
L
S
S
S
M
D
K
T
V
Site 93
S624
K
N
Y
F
L
L
S
S
S
M
D
K
T
V
R
Site 94
S625
N
Y
F
L
L
S
S
S
M
D
K
T
V
R
L
Site 95
T629
L
S
S
S
M
D
K
T
V
R
L
W
H
I
S
Site 96
Y662
F
H
P
R
D
D
R
Y
F
L
S
G
S
L
D
Site 97
S665
R
D
D
R
Y
F
L
S
G
S
L
D
G
K
L
Site 98
S667
D
R
Y
F
L
S
G
S
L
D
G
K
L
R
L
Site 99
T696
D
G
Q
T
K
L
I
T
A
A
N
F
C
Q
N
Site 100
Y706
N
F
C
Q
N
G
K
Y
A
V
I
G
T
Y
D
Site 101
Y719
Y
D
G
R
C
I
F
Y
D
T
E
H
L
K
Y
Site 102
Y726
Y
D
T
E
H
L
K
Y
H
T
Q
I
H
V
R
Site 103
S734
H
T
Q
I
H
V
R
S
T
R
G
R
N
K
V
Site 104
T735
T
Q
I
H
V
R
S
T
R
G
R
N
K
V
G
Site 105
T746
N
K
V
G
R
K
I
T
G
I
E
P
L
P
G
Site 106
T760
G
E
N
K
I
L
V
T
S
N
D
S
R
I
R
Site 107
Y769
N
D
S
R
I
R
L
Y
D
L
R
D
L
S
L
Site 108
S775
L
Y
D
L
R
D
L
S
L
S
M
K
Y
K
G
Site 109
S777
D
L
R
D
L
S
L
S
M
K
Y
K
G
Y
V
Site 110
Y783
L
S
M
K
Y
K
G
Y
V
N
S
S
S
Q
I
Site 111
S786
K
Y
K
G
Y
V
N
S
S
S
Q
I
K
A
S
Site 112
S787
Y
K
G
Y
V
N
S
S
S
Q
I
K
A
S
F
Site 113
S788
K
G
Y
V
N
S
S
S
Q
I
K
A
S
F
S
Site 114
S793
S
S
S
Q
I
K
A
S
F
S
H
D
F
T
Y
Site 115
T799
A
S
F
S
H
D
F
T
Y
L
V
S
G
S
E
Site 116
Y800
S
F
S
H
D
F
T
Y
L
V
S
G
S
E
D
Site 117
S805
F
T
Y
L
V
S
G
S
E
D
K
Y
V
Y
I
Site 118
Y809
V
S
G
S
E
D
K
Y
V
Y
I
W
S
T
Y
Site 119
Y811
G
S
E
D
K
Y
V
Y
I
W
S
T
Y
H
D
Site 120
Y816
Y
V
Y
I
W
S
T
Y
H
D
L
S
K
F
T
Site 121
S820
W
S
T
Y
H
D
L
S
K
F
T
S
V
R
R
Site 122
S824
H
D
L
S
K
F
T
S
V
R
R
D
R
N
D
Site 123
S857
P
N
P
S
L
M
L
S
L
D
V
Q
S
E
K
Site 124
S865
L
D
V
Q
S
E
K
S
E
G
N
E
K
S
E
Site 125
S871
K
S
E
G
N
E
K
S
E
D
A
E
V
L
D
Site 126
T880
D
A
E
V
L
D
A
T
P
S
G
I
M
K
T
Site 127
S882
E
V
L
D
A
T
P
S
G
I
M
K
T
D
N
Site 128
T890
G
I
M
K
T
D
N
T
E
V
L
L
S
A
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation