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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TJAP1
Full Name:
Tight junction-associated protein 1
Alias:
FLJ14207; PILT; Tight junction associated protein 1 (peripheral); Tight junction protein 4; TJP4
Type:
Adhesion
Mass (Da):
61821
Number AA:
557
UniProt ID:
Q5JTD0
International Prot ID:
IPI00010544
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005911
GO:0005923
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
L
R
L
E
I
P
G
S
R
L
E
Q
E
E
P
Site 2
T37
L
E
Q
E
E
P
L
T
D
A
E
R
M
K
L
Site 3
S58
E
L
R
R
R
L
A
S
A
T
R
R
T
E
A
Site 4
T60
R
R
R
L
A
S
A
T
R
R
T
E
A
L
E
Site 5
T63
L
A
S
A
T
R
R
T
E
A
L
E
R
E
L
Site 6
S84
L
E
L
E
L
G
Q
S
R
E
E
L
D
K
F
Site 7
S101
K
F
R
R
L
Q
N
S
Y
T
A
S
Q
R
T
Site 8
Y102
F
R
R
L
Q
N
S
Y
T
A
S
Q
R
T
N
Site 9
T103
R
R
L
Q
N
S
Y
T
A
S
Q
R
T
N
Q
Site 10
S105
L
Q
N
S
Y
T
A
S
Q
R
T
N
Q
E
L
Site 11
T118
E
L
E
D
K
L
H
T
L
A
S
L
S
H
S
Site 12
S121
D
K
L
H
T
L
A
S
L
S
H
S
W
I
F
Site 13
T139
K
A
E
M
D
R
K
T
L
D
W
E
I
V
E
Site 14
S208
M
V
R
K
H
L
H
S
G
Q
E
A
A
S
P
Site 15
S214
H
S
G
Q
E
A
A
S
P
G
P
A
P
S
L
Site 16
S241
R
V
L
E
K
P
E
S
L
L
L
N
S
A
Q
Site 17
S246
P
E
S
L
L
L
N
S
A
Q
S
G
S
A
G
Site 18
S249
L
L
L
N
S
A
Q
S
G
S
A
G
R
P
L
Site 19
S276
G
V
P
G
D
P
A
S
P
P
A
P
G
S
P
Site 20
S282
A
S
P
P
A
P
G
S
P
T
P
Q
P
N
G
Site 21
T284
P
P
A
P
G
S
P
T
P
Q
P
N
G
E
C
Site 22
S293
Q
P
N
G
E
C
H
S
L
G
T
A
R
G
S
Site 23
T296
G
E
C
H
S
L
G
T
A
R
G
S
P
E
E
Site 24
S300
S
L
G
T
A
R
G
S
P
E
E
E
L
P
L
Site 25
Y316
A
F
E
K
L
N
P
Y
P
T
P
S
P
P
H
Site 26
T318
E
K
L
N
P
Y
P
T
P
S
P
P
H
P
L
Site 27
S320
L
N
P
Y
P
T
P
S
P
P
H
P
L
Y
P
Site 28
Y326
P
S
P
P
H
P
L
Y
P
G
R
R
V
I
E
Site 29
S335
G
R
R
V
I
E
F
S
E
D
K
V
R
I
P
Site 30
S345
K
V
R
I
P
R
N
S
P
L
P
N
C
T
Y
Site 31
T351
N
S
P
L
P
N
C
T
Y
A
T
R
Q
A
I
Site 32
Y352
S
P
L
P
N
C
T
Y
A
T
R
Q
A
I
S
Site 33
T354
L
P
N
C
T
Y
A
T
R
Q
A
I
S
L
S
Site 34
S359
Y
A
T
R
Q
A
I
S
L
S
L
V
E
E
G
Site 35
S361
T
R
Q
A
I
S
L
S
L
V
E
E
G
S
E
Site 36
S367
L
S
L
V
E
E
G
S
E
R
A
R
P
S
P
Site 37
S373
G
S
E
R
A
R
P
S
P
V
P
S
T
P
A
Site 38
S377
A
R
P
S
P
V
P
S
T
P
A
S
A
Q
A
Site 39
T378
R
P
S
P
V
P
S
T
P
A
S
A
Q
A
S
Site 40
S381
P
V
P
S
T
P
A
S
A
Q
A
S
P
H
H
Site 41
S385
T
P
A
S
A
Q
A
S
P
H
H
Q
P
S
P
Site 42
S391
A
S
P
H
H
Q
P
S
P
A
P
L
T
L
S
Site 43
T396
Q
P
S
P
A
P
L
T
L
S
A
P
A
S
S
Site 44
S402
L
T
L
S
A
P
A
S
S
A
S
S
E
E
D
Site 45
S405
S
A
P
A
S
S
A
S
S
E
E
D
L
L
V
Site 46
S406
A
P
A
S
S
A
S
S
E
E
D
L
L
V
S
Site 47
T422
Q
R
A
F
V
D
R
T
P
P
P
A
A
V
A
Site 48
S449
L
Q
R
H
F
A
H
S
P
A
D
R
D
E
V
Site 49
S461
D
E
V
V
Q
A
P
S
A
R
P
E
E
S
E
Site 50
T473
E
S
E
L
L
L
P
T
E
P
D
S
G
F
P
Site 51
S477
L
L
P
T
E
P
D
S
G
F
P
R
E
E
E
Site 52
S491
E
E
L
N
L
P
I
S
P
E
E
E
R
Q
S
Site 53
S498
S
P
E
E
E
R
Q
S
L
L
P
I
N
R
G
Site 54
T506
L
L
P
I
N
R
G
T
E
E
G
P
G
T
S
Site 55
T512
G
T
E
E
G
P
G
T
S
H
T
E
G
R
A
Site 56
T515
E
G
P
G
T
S
H
T
E
G
R
A
W
P
L
Site 57
S524
G
R
A
W
P
L
P
S
S
S
R
P
Q
R
S
Site 58
S525
R
A
W
P
L
P
S
S
S
R
P
Q
R
S
P
Site 59
S526
A
W
P
L
P
S
S
S
R
P
Q
R
S
P
K
Site 60
S531
S
S
S
R
P
Q
R
S
P
K
R
M
G
V
H
Site 61
S545
H
H
L
H
R
K
D
S
L
T
Q
A
Q
E
Q
Site 62
T547
L
H
R
K
D
S
L
T
Q
A
Q
E
Q
G
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation